SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_001145339
Gene Symbol: MDM2
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839816A>G COSM1586716 TCGA-B5-A11E-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-183-3p gacaaccAATTCAaa GUGAAUUA m6b Disrupted HPSD3_2291_G3082.1_69233604
hsa-miR-219a-2-3p gacaacCAATTCaaa AGAAUUGU m6b Disrupted HPSD3_2291_G3082.1_69233604
hsa-miR-219b-3p gacaacCAATTCaaa AGAAUUGC m6b Disrupted HPSD3_2291_G3082.1_69233604
hsa-miR-3610 gacaaCCGATTCaaa GAAUCGGA m7a Created HPSD3_2291_G3082.1_69233604
hsa-miR-4452 gacaaccAATTCAAa UUGAAUUC m7a Disrupted HPSD3_2291_G3082.1_69233604
hsa-miR-183-3p gacaaccAATTCAaa GUGAAUUA m6b Disrupted HPSD3_2291_G3082.1_69233604
hsa-miR-219a-2-3p gacaacCAATTCaaa AGAAUUGU m6b Disrupted HPSD3_2291_G3082.1_69233604
hsa-miR-219b-3p gacaacCAATTCaaa AGAAUUGC m6b Disrupted HPSD3_2291_G3082.1_69233604
hsa-miR-3610 gacaaCCGATTCaaa GAAUCGGA m7a Created HPSD3_2291_G3082.1_69233604
hsa-miR-4452 gacaaccAATTCAAa UUGAAUUC m7a Disrupted HPSD3_2291_G3082.1_69233604

Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839764G>A COSM1188547 LC_S4 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-153-3p tttacaTATGCAAag UUGCAUAG m7a Created HPSD3_2290_G3081.1_69233538
hsa-miR-3680-3p tttacatATGCAAAg UUUUGCAU m7b Created HPSD3_2290_G3081.1_69233538
hsa-miR-448 tttacATATGCAAag UUGCAUAU m8a Created HPSD3_2290_G3081.1_69233538
hsa-miR-507 tttacatGTGCAAAg UUUUGCAC m7b Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-557 tttacatGTGCAAAg GUUUGCAC m7b Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-5589-3p tttaCATGTGCAaag UGCACAUG m8a Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-153-3p tttacaTATGCAAag UUGCAUAG m7a Created HPSD3_2290_G3081.1_69233538
hsa-miR-3680-3p tttacatATGCAAAg UUUUGCAU m7b Created HPSD3_2290_G3081.1_69233538
hsa-miR-448 tttacATATGCAAag UUGCAUAU m8a Created HPSD3_2290_G3081.1_69233538
hsa-miR-507 tttacatGTGCAAAg UUUUGCAC m7b Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-557 tttacatGTGCAAAg GUUUGCAC m7b Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-5589-3p tttaCATGTGCAaag UGCACAUG m8a Disrupted HPSD3_2290_G3081.1_69233538

Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839750G>T COSM48558 16857 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-15a-3p atcttATGGCCTGct CAGGCCAU m8a Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-1972 atcttaTGGCCTGct UCAGGCCA m7b Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-4742-5p atcttaTTGCCTGct UCAGGCAA m7b Created HPSD3_2290_G3081.1_69233538

Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839748A>T COSM1363884 TCGA-AZ-6600-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-15a-3p acatcttATGGCCTg CAGGCCAU m7b Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-3926 acatctTTTGGCCtg UGGCCAAA m7b Created HPSD3_2290_G3081.1_69233538
hsa-miR-15a-3p acatcttATGGCCTg CAGGCCAU m7b Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-3926 acatctTTTGGCCtg UGGCCAAA m7b Created HPSD3_2290_G3081.1_69233538

Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839748A>G COSM1363882 TCGA-AZ-6599-01 [large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-15a-3p acatcttATGGCCTg CAGGCCAU m7b Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-4717-5p acatcttGTGGCCTg UAGGCCAC m7b Created HPSD3_2290_G3081.1_69233538
hsa-miR-15a-3p acatcttATGGCCTg CAGGCCAU m7b Disrupted HPSD3_2290_G3081.1_69233538
hsa-miR-4717-5p acatcttGTGGCCTg UAGGCCAC m7b Created HPSD3_2290_G3081.1_69233538

Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839469A>G COSM4976756 1N52-VS-1T52 [oesophagus][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-139-5p aaaaACTGTAGtgaa UCUACAGU m7b Created HPSD3_2288_G3079.1_69233253
hsa-miR-4328 aAAAACTGtagtgaa CCAGUUUU m7b Created HPSD3_2288_G3079.1_69233253
hsa-miR-4999-3p aaaaactGTAGTGAa UCACUACC m7a Created HPSD3_2288_G3079.1_69233253
hsa-miR-582-5p aaaAACTGTAgtgaa UUACAGUU m7b Created HPSD3_2288_G3079.1_69233253
hsa-miR-625-3p aaaaaCTATAGTgaa GACUAUAG m7b Disrupted HPSD3_2288_G3079.1_69233253
hsa-miR-139-5p aaaaACTGTAGtgaa UCUACAGU m7b Created HPSD3_2288_G3079.1_69233253
hsa-miR-4328 aAAAACTGtagtgaa CCAGUUUU m7b Created HPSD3_2288_G3079.1_69233253
hsa-miR-4999-3p aaaaactGTAGTGAa UCACUACC m7a Created HPSD3_2288_G3079.1_69233253
hsa-miR-582-5p aaaAACTGTAgtgaa UUACAGUU m7b Created HPSD3_2288_G3079.1_69233253
hsa-miR-625-3p aaaaaCTATAGTgaa GACUAUAG m7b Disrupted HPSD3_2288_G3079.1_69233253

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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