SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_001145339
Gene Symbol: MDM2
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Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839764G>A COSM1188547 LC_S4 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-153-3p tttacaTATGCAAag UUGCAUAG m7a Created HPKMA_3377_G3930.1_69233528
hsa-miR-3680-3p tttacatATGCAAAg UUUUGCAU m7b Created HPKMA_3377_G3930.1_69233528
hsa-miR-448 tttacATATGCAAag UUGCAUAU m8a Created HPKMA_3377_G3930.1_69233528
hsa-miR-507 tttacatGTGCAAAg UUUUGCAC m7b Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-557 tttacatGTGCAAAg GUUUGCAC m7b Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-5589-3p tttaCATGTGCAaag UGCACAUG m8a Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-153-3p tttacaTATGCAAag UUGCAUAG m7a Created HPKMA_3377_G3930.1_69233528
hsa-miR-3680-3p tttacatATGCAAAg UUUUGCAU m7b Created HPKMA_3377_G3930.1_69233528
hsa-miR-448 tttacATATGCAAag UUGCAUAU m8a Created HPKMA_3377_G3930.1_69233528
hsa-miR-507 tttacatGTGCAAAg UUUUGCAC m7b Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-557 tttacatGTGCAAAg GUUUGCAC m7b Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-5589-3p tttaCATGTGCAaag UGCACAUG m8a Disrupted HPKMA_3377_G3930.1_69233528

Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839750G>T COSM48558 16857 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-15a-3p atcttATGGCCTGct CAGGCCAU m8a Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-1972 atcttaTGGCCTGct UCAGGCCA m7b Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-4742-5p atcttaTTGCCTGct UCAGGCAA m7b Created HPKMA_3377_G3930.1_69233528

Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839748A>T COSM1363884 TCGA-AZ-6600-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-15a-3p acatcttATGGCCTg CAGGCCAU m7b Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-3926 acatctTTTGGCCtg UGGCCAAA m7b Created HPKMA_3377_G3930.1_69233528
hsa-miR-15a-3p acatcttATGGCCTg CAGGCCAU m7b Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-3926 acatctTTTGGCCtg UGGCCAAA m7b Created HPKMA_3377_G3930.1_69233528

Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839748A>G COSM1363882 TCGA-AZ-6599-01 [large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-15a-3p acatcttATGGCCTg CAGGCCAU m7b Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-4717-5p acatcttGTGGCCTg UAGGCCAC m7b Created HPKMA_3377_G3930.1_69233528
hsa-miR-15a-3p acatcttATGGCCTg CAGGCCAU m7b Disrupted HPKMA_3377_G3930.1_69233528
hsa-miR-4717-5p acatcttGTGGCCTg UAGGCCAC m7b Created HPKMA_3377_G3930.1_69233528

Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839660T>G COSM240627 WA22 [prostate][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-28-3p aATCTAGTttgcccc CACUAGAU m7b Disrupted HPKMA_3376_G3929.1_69233434
hsa-miR-4470 aatctaGTTTGCCcc UGGCAAAC m7b Disrupted HPKMA_3376_G3929.1_69233434
hsa-miR-4714-3p aatcTAGGTTGcccc CCAACCUA m7b Created HPKMA_3376_G3929.1_69233434
hsa-miR-708-3p aaTCTAGTTtgcccc CAACUAGA m7b (m7b->m6b) HPKMA_3376_G3929.1_69233434
hsa-miR-7844-5p aatCTAGTTTgcccc AAAACUAG m7b Disrupted HPKMA_3376_G3929.1_69233434

Mutation Mutation ID Sample Name Cancer Type
chr12:g.68839646A>T COSM3667209 CHC306T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4639-3p agaaGAGAGTGtgga UCACUCUC m7b Disrupted HPKMA_3376_G3929.1_69233434
hsa-miR-603 agaagAGTGTGTGga CACACACU m8a Created HPKMA_3376_G3929.1_69233434
hsa-miR-4639-3p agaaGAGAGTGtgga UCACUCUC m7b Disrupted HPKMA_3376_G3929.1_69233434
hsa-miR-603 agaagAGTGTGTGga CACACACU m8a Created HPKMA_3376_G3929.1_69233434

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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