SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_001005291
Gene Symbol: SREBF1
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr17:g.17819654G>A COSM2740327 LS180 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1273f cccgcCCATCTCCtt GGAGAUGG m8a Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-139-3p cccgccCGTCTCCtt UGGAGACG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-483-5p cccgCCCGTCTcctt AAGACGGG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6888-5p cccgcccATCTCCTt AAGGAGAU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-1228-5p cCCGCCCAtctcctt GUGGGCGG m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-1273f cccgcCCATCTCCtt GGAGAUGG m8a Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-139-3p cccgccCGTCTCCtt UGGAGACG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-483-5p cccgCCCGTCTcctt AAGACGGG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6888-5p cccgcccATCTCCTt AAGGAGAU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620

Mutation Mutation ID Sample Name Cancer Type
chr17:g.17819651T>G COSM4264104 KM12 [large_intestine][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-139-3p gccCGTCTCCttgca UGGAGACG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4428 gcccgTCTCCTTGca CAAGGAGA m8a Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4708-3p gcccgtcGCCTTGCa AGCAAGGC m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-483-5p gCCCGTCTccttgca AAGACGGG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-139-3p gccCGTCTCCttgca UGGAGACG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4428 gcccgTCTCCTTGca CAAGGAGA m8a Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4708-3p gcccgtcGCCTTGCa AGCAAGGC m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-483-5p gCCCGTCTccttgca AAGACGGG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620

Mutation Mutation ID Sample Name Cancer Type
chr17:g.17819649C>T COSM4505377 CSCC-19-T [skin][head_neck][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-139-3p cCGTCTCCttgcaca UGGAGACG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-19a-3p ccgtctcTTTGCACa UGUGCAAA m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-19b-3p ccgtctcTTTGCACa UGUGCAAA m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4311 ccgTCTCTTTgcaca GAAAGAGA m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4428 ccgTCTCCTTGcaca CAAGGAGA m8a Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4708-3p ccgtctCCTTGCaca AGCAAGGC m6b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-518a-5p ccgtctCTTTGCAca CUGCAAAG m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-527 ccgtctCTTTGCAca CUGCAAAG m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-548aw ccgtctcTTTGCACa GUGCAAAA m7a Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-139-3p cCGTCTCCttgcaca UGGAGACG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-19a-3p ccgtctcTTTGCACa UGUGCAAA m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-19b-3p ccgtctcTTTGCACa UGUGCAAA m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4311 ccgTCTCTTTgcaca GAAAGAGA m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4428 ccgTCTCCTTGcaca CAAGGAGA m8a Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4708-3p ccgtctCCTTGCaca AGCAAGGC m6b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-518a-5p ccgtctCTTTGCAca CUGCAAAG m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-527 ccgtctCTTTGCAca CUGCAAAG m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-548aw ccgtctcTTTGCACa GUGCAAAA m7a Created HHRBL_6131_BCBL1-2of3-SCL_9620

Mutation Mutation ID Sample Name Cancer Type
chr17:g.17819601C>G COSM3717211 HX29T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-134-5p tgaCAGTCACAgctg UGUGACUG m8a Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-3118 tgaCAGTCACAgctg UGUGACUG m8a Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4420 tgaCAGTGACagctg GUCACUGA m7a Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4439 tgaCAGTCACagctg GUGACUGA m7a Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6760-3p tGACAGTGacagctg ACACUGUC m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6773-3p tgacaGTGACAGctg ACUGUCAC m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-943 tgACAGTCAcagctg CUGACUGU m7b (m7b->m6b) HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-134-5p tgaCAGTCACAgctg UGUGACUG m8a Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-3118 tgaCAGTCACAgctg UGUGACUG m8a Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4420 tgaCAGTGACagctg GUCACUGA m7a Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4439 tgaCAGTCACagctg GUGACUGA m7a Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6760-3p tGACAGTGacagctg ACACUGUC m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6773-3p tgacaGTGACAGctg ACUGUCAC m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-943 tgACAGTCAcagctg CUGACUGU m7b (m7b->m6b) HHRBL_6131_BCBL1-2of3-SCL_9620

Mutation Mutation ID Sample Name Cancer Type
chr17:g.17819594G>A COSM1240315 ESO-859 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1237-5p cacagctGCCCCCac CGGGGGCG m6b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4488 cacagctGCCCCCac AGGGGGCG m6b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4697-5p cacagctGCCCCCac AGGGGGCG m6b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-486-3p cacagCTGCCCCcac CGGGGCAG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6751-5p cacagctACCCCCAc UUGGGGGU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6752-5p cacagctACCCCCac GGGGGGUG m6b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6803-5p cacagctACCCCCAc CUGGGGGU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6835-5p cacagcTACCCCCac AGGGGGUA m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620

Mutation Mutation ID Sample Name Cancer Type
chr17:g.17819593C>T COSM1227543 587246 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1237-5p acagctGCCCCCacg CGGGGGCG m6b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-3144-5p acagctGTCCCCacg AGGGGACC m6b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4447 acagctgCCCCCACg GGUGGGGG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4472 acagctgCCCCCACg GGUGGGGG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4488 acagctGCCCCCacg AGGGGGCG m6b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4652-5p acagctGTCCCCacg AGGGGACU m6b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4697-5p acagctGCCCCCacg AGGGGGCG m6b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-486-3p acagCTGCCCCcacg CGGGGCAG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-491-5p acagctgTCCCCACg AGUGGGGA m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6810-5p acagctGTCCCCAcg AUGGGGAC m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620

Mutation Mutation ID Sample Name Cancer Type
chr17:g.17819587C>T COSM1609906 BN24T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4447 gCCCCCACggcagcc GGUGGGGG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4472 gCCCCCACggcagcc GGUGGGGG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4659a-5p gccccCATGGCAGcc CUGCCAUG m8a Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4659b-5p gccccCATGGCAgcc UUGCCAUG m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4769-3p gcccccATGGCAGcc UCUGCCAU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6817-5p gcccccATGGCAGcc UCUGCCAU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4447 gCCCCCACggcagcc GGUGGGGG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4472 gCCCCCACggcagcc GGUGGGGG m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4659a-5p gccccCATGGCAGcc CUGCCAUG m8a Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4659b-5p gccccCATGGCAgcc UUGCCAUG m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-4769-3p gcccccATGGCAGcc UCUGCCAU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6817-5p gcccccATGGCAGcc UCUGCCAU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620

Mutation Mutation ID Sample Name Cancer Type
chr17:g.17819577T>C COSM3773772 TCGA-BP-4159-01 [kidney][NS][carcinoma][clear_cell_renal_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-6085 cAGCCCCTgtaacga AAGGGGCU m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6813-5p cAGCCCCTGtaacga CAGGGGCU m8a (m8a->m7a) HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6846-5p cAGCCCCCgtaacga UGGGGGCU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6848-5p cAGCCCCCgtaacga UGGGGGCU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-7151-3p cagccCCTGTAacga CUACAGGC m6b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6085 cAGCCCCTgtaacga AAGGGGCU m7b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6813-5p cAGCCCCTGtaacga CAGGGGCU m8a (m8a->m7a) HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6846-5p cAGCCCCCgtaacga UGGGGGCU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-6848-5p cAGCCCCCgtaacga UGGGGGCU m7b Created HHRBL_6131_BCBL1-2of3-SCL_9620
hsa-miR-7151-3p cagccCCTGTAacga CUACAGGC m6b Disrupted HHRBL_6131_BCBL1-2of3-SCL_9620

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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