SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_001001411
Gene Symbol: ZNF676

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr19:g.22181024C>G COSM4131562 Detroit_562 [upper_aerodigestive_tract][pharynx][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1251-3p aatgtgGCAAAGCtt CGCUUUGC m7b Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-1260a aatGTGGGAaagctt AUCCCACC m6b Created HPCB1_20547_G25790.1_22363816
hsa-miR-1260b aatGTGGGAaagctt AUCCCACC m6b Created HPCB1_20547_G25790.1_22363816
hsa-miR-188-3p aaTGTGGGAaagctt CUCCCACA m7b (m6b->m7b) HPCB1_20547_G25790.1_22363816
hsa-miR-3064-3p aaTGTGGCAAagctt UUGCCACA m8a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-3156-3p aatGTGGGAaagctt CUCCCACU m6b Created HPCB1_20547_G25790.1_22363816
hsa-miR-4715-3p aatGTGGCAaagctt GUGCCACC m6b Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-4776-3p aatgTGGCAAagctt CUUGCCAU m6b Disrupted HPCB1_20547_G25790.1_22363816

Mutation Mutation ID Sample Name Cancer Type
chr19:g.22181018T>A COSM3404034 TCGA-32-1977-01 [central_nervous_system][brain][glioma][astrocytoma_Grade_IV]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-320a gcaaAGCTTTTaatc AAAAGCUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-320b gcaaAGCTTTTaatc AAAAGCUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-320c gcaaAGCTTTTaatc AAAAGCUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-320d gcaaAGCTTTTaatc AAAAGCUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-4429 gcaaAGCTTTTaatc AAAAGCUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-548e-5p gcaaaGCTTTTaatc CAAAAGCA m6b Disrupted HPCB1_20547_G25790.1_22363816

Mutation Mutation ID Sample Name Cancer Type
chr19:g.22181017T>A COSM303649 MD-324 [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-320a caaAGCTTTTaatcg AAAAGCUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-320b caaAGCTTTTaatcg AAAAGCUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-320c caaAGCTTTTaatcg AAAAGCUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-320d caaAGCTTTTaatcg AAAAGCUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-4429 caaAGCTTTTaatcg AAAAGCUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-548e-5p caaaGCTTTTaatcg CAAAAGCA m6b Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-633 caaagCTATTAatcg CUAAUAGU m6b Created HPCB1_20547_G25790.1_22363816
hsa-miR-7705 caaAGCTATTaatcg AAUAGCUC m7a Created HPCB1_20547_G25790.1_22363816

Mutation Mutation ID Sample Name Cancer Type
chr19:g.22181016T>A COSM710717 TCGA-22-5489-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-320a aaAGCTTTTaatcga AAAAGCUG m7a (m7a->m6a) HPCB1_20547_G25790.1_22363816
hsa-miR-320b aaAGCTTTTaatcga AAAAGCUG m7a (m7a->m6a) HPCB1_20547_G25790.1_22363816
hsa-miR-320c aaAGCTTTTaatcga AAAAGCUG m7a (m7a->m6a) HPCB1_20547_G25790.1_22363816
hsa-miR-320d aaAGCTTTTaatcga AAAAGCUG m7a (m7a->m6a) HPCB1_20547_G25790.1_22363816
hsa-miR-4429 aaAGCTTTTaatcga AAAAGCUG m7a (m7a->m6a) HPCB1_20547_G25790.1_22363816
hsa-miR-548e-5p aaaGCTTTTaatcga CAAAAGCA m6b Disrupted HPCB1_20547_G25790.1_22363816

Mutation Mutation ID Sample Name Cancer Type
chr19:g.22181012T>CT COSM4169697 2171754 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4424 cttTTAACTCgatcct AGAGUUAA m7b Created HPCB1_20547_G25790.1_22363816
hsa-miR-4444 cttttAACTCGAtcct CUCGAGUU m7b Created HPCB1_20547_G25790.1_22363816

Mutation Mutation ID Sample Name Cancer Type
chr19:g.22181011C>T COSM3531661 TCGA-EE-A3JI-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4275 tttTAATTGatcctc CCAAUUAC m6b Created HPCB1_20547_G25790.1_22363816
Mutation Mutation ID Sample Name Cancer Type
chr19:g.22181010G>A COSM299654 TCGA-AA-A010-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr19:g.22181007TC>C COSM4169696 2171754 [haematopoietic_and_lymphoid_tissue][NS][haematopoietic_neoplasm][acute_myeloid_leukaemia]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1185-5p taatcgATCCTCaatc AGAGGAUA m6b Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-1224-5p taatcgaTCCTCAatc GUGAGGAC m6b Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-1304-5p taatcgaCCTCAAtc UUUGAGGC m6b Created HPCB1_20547_G25790.1_22363816
hsa-miR-3605-5p taatcgATCCTCAatc UGAGGAUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-3679-5p taatcgATCCTCAatc UGAGGAUA m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-6858-5p taatcgaTCCTCAatc GUGAGGAG m6b Disrupted HPCB1_20547_G25790.1_22363816

Mutation Mutation ID Sample Name Cancer Type
chr19:g.22181007C>T COSM2747880 TCGA-EB-A3Y7-01 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1185-5p aatcgATCCTCaatc AGAGGAUA m6b Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-1224-5p aatcgaTCCTCAatc GUGAGGAC m6b Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-3605-5p aatcgATCCTCAatc UGAGGAUG m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-3679-5p aatcgATCCTCAatc UGAGGAUA m7a Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-4461 aatcgatTCTCAATc GAUUGAGA m7b Created HPCB1_20547_G25790.1_22363816
hsa-miR-580-3p aatcgATTCTCAAtc UUGAGAAU m8a Created HPCB1_20547_G25790.1_22363816
hsa-miR-6858-5p aatcgaTCCTCAatc GUGAGGAG m6b Disrupted HPCB1_20547_G25790.1_22363816

Mutation Mutation ID Sample Name Cancer Type
chr19:g.22181000C>T COSM3892140 TCGA-GN-A268-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-541-5p cctcAATCCTTacta AAAGGAUU m7b Disrupted HPCB1_20547_G25790.1_22363816
hsa-miR-6507-5p cctcaATTCTTacta GAAGAAUA m6b Created HPCB1_20547_G25790.1_22363816

Mutation Mutation ID Sample Name Cancer Type
chr19:g.22179475C>A COSN1213033 HCC17T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-323a-3p aaacatTAATGTaat CACAUUAC m6b Created HPCB1_20542_G25785.1_22362284
hsa-miR-409-3p aAACATTCatgtaat GAAUGUUG m7a Disrupted HPCB1_20542_G25785.1_22362284
hsa-miR-4666a-5p aaacattCATGTAat AUACAUGU m6b Disrupted HPCB1_20542_G25785.1_22362284

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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