SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_000938
Gene Symbol: POLR2B
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030975T>C COSM326212 585276 [lung][NS][carcinoma][small_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1298-5p ccgCGAATGAtgagt UUCAUUCG m7b Disrupted HHFKP_110050_cluster-17142_18_400
hsa-miR-382-3p ccgcGAATGATgagt AAUCAUUC m7b Disrupted HHFKP_110050_cluster-17142_18_400

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030970G>A COSM276838 T2944 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3677-3p ttgcaCCACGAatga CUCGUGGG m6b Created HHFKP_110050_cluster-17142_18_400
hsa-miR-4746-3p ttGCACCGCgaatga AGCGGUGC m7b (m7b->m6b) HHFKP_110050_cluster-17142_18_400
hsa-miR-579-5p ttgcACCGCGAatga UCGCGGUU m7a Disrupted HHFKP_110050_cluster-17142_18_400

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030968C>T COSM4125336 TCGA-BR-6452-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4746-3p tattGCACCGCgaat AGCGGUGC m7b Disrupted HHFKP_110050_cluster-17142_18_400
hsa-miR-579-5p tattgcACCGCGAat UCGCGGUU m7a Disrupted HHFKP_110050_cluster-17142_18_400

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030966C>T COSM4125335 TCGA-BR-8361-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-338-5p agTATTGTaccgcga AACAAUAU m6b Created HHFKP_110050_cluster-17142_18_400
hsa-miR-4746-3p agtattGCACCGCga AGCGGUGC m7b Disrupted HHFKP_110050_cluster-17142_18_400

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030960G>T COSM1056384 TCGA-AP-A059-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-154-3p tcTATGATTattgca AAUCAUAC m7a (m6a->m7a) HHFKP_110050_cluster-17142_18_400
hsa-miR-376a-3p TCTATGATtattgca AUCAUAGA m8a Created HHFKP_110050_cluster-17142_18_400
hsa-miR-376b-3p TCTATGATtattgca AUCAUAGA m8a Created HHFKP_110050_cluster-17142_18_400
hsa-miR-487a-3p tcTATGATTattgca AAUCAUAC m7a (m6a->m7a) HHFKP_110050_cluster-17142_18_400

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030923G>A COSM1221503 CPCG0094-F1 [prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3607-5p gccttaCACATGCaa GCAUGUGA m7a Created HHFKP_110050_cluster-17142_18_400
hsa-miR-4666b gccttacACATGCAa UUGCAUGU m7b Created HHFKP_110050_cluster-17142_18_400
hsa-miR-511-3p gcctTACACATgcaa AAUGUGUA m7b Created HHFKP_110050_cluster-17142_18_400
Mutation Mutation ID Sample Name Cancer Type
chr4:g.57030922C>G COSM734033 TCGA-22-5492-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr4:g.57010459G>A COSM4845763 TCGA-IR-A3LA-01 [cervix][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-379-3p gacaGTTACATAata UAUGUAAC m8a Created HHFKP_110044_cluster-17142_12_62
hsa-miR-380-3p gacagTTACATAata UAUGUAAU m7a Created HHFKP_110044_cluster-17142_12_62
hsa-miR-3924 gacagtTACATAata AUAUGUAU m6b Created HHFKP_110044_cluster-17142_12_62
hsa-miR-411-3p gacaGTTACATAata UAUGUAAC m8a Created HHFKP_110044_cluster-17142_12_62
hsa-miR-4495 gacagTTACATaata AAUGUAAA m6b Created HHFKP_110044_cluster-17142_12_62
hsa-miR-491-3p gacagtTGCATAAta CUUAUGCA m7b Disrupted HHFKP_110044_cluster-17142_12_62

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57010451A>C COSM3783813 TCGA-EJ-7782-01 [prostate][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4440 aaaaCCACGACAgtt UGUCGUGG m8a Created HHFKP_110044_cluster-17142_12_62
hsa-miR-659-3p aaAACCAAGacagtt CUUGGUUC m7a (m7a->m6a) HHFKP_110044_cluster-17142_12_62

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57010447A>C COSM4777045 2318492 [breast][NS][carcinoma][ER-PR-positive_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-19a-5p taGCAAAACcaagac AGUUUUGC m7b (m7b->m6b) HHFKP_110044_cluster-17142_12_62
hsa-miR-19b-1-5p taGCAAAACcaagac AGUUUUGC m7b (m7b->m6b) HHFKP_110044_cluster-17142_12_62
hsa-miR-19b-2-5p taGCAAAACcaagac AGUUUUGC m7b (m7b->m6b) HHFKP_110044_cluster-17142_12_62
hsa-miR-29b-2-5p tagcaAAACCAagac CUGGUUUC m6b Disrupted HHFKP_110044_cluster-17142_12_62
hsa-miR-3940-5p tagcaAACCCAagac GUGGGUUG m6b Created HHFKP_110044_cluster-17142_12_62
hsa-miR-4507 tagcaAACCCAagac CUGGGUUG m6b Created HHFKP_110044_cluster-17142_12_62
hsa-miR-5087 tagCAAACCCaagac GGGUUUGU m7a Created HHFKP_110044_cluster-17142_12_62
hsa-miR-629-5p tagcAAACCCAagac UGGGUUUA m7a Created HHFKP_110044_cluster-17142_12_62
hsa-miR-635 tagcaaaCCCAAGac ACUUGGGC m6b Created HHFKP_110044_cluster-17142_12_62
hsa-miR-659-3p tagcaaAACCAAGac CUUGGUUC m7a Disrupted HHFKP_110044_cluster-17142_12_62
hsa-miR-6774-5p tagcaaaCCCAAGac ACUUGGGC m6b Created HHFKP_110044_cluster-17142_12_62
hsa-miR-6839-3p tagcAAACCCAAgac UUGGGUUU m8a Created HHFKP_110044_cluster-17142_12_62

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57006872G>A COSM1328471 TCGA-61-1740-01 [ovary][NS][carcinoma][serous_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1238-3p attgatCGAGGAAag CUUCCUCG m7b Disrupted HHFKP_110041_cluster-17142_9_91
hsa-miR-502-5p attgatCAAGGAaag AUCCUUGC m6b Created HHFKP_110041_cluster-17142_9_91

Mutation Mutation ID Sample Name Cancer Type
chr4:g.57006871C>T COSM3604685 TCGA-EE-A2GC-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1238-3p tattgatCGAGGAAa CUUCCUCG m7b Disrupted HHFKP_110041_cluster-17142_9_91
hsa-miR-670-3p tattgatTGAGGAAa UUUCCUCA m7b Created HHFKP_110041_cluster-17142_9_91

Mutation Mutation ID Sample Name Cancer Type
chr4:g.56999700C>T COSM4509835 CSCC-27-T [skin][head_neck][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1301-5p ttgtgttTAGAGCat CGCUCUAG m6b Created HHFKP_110038_cluster-17142_6_16
hsa-miR-146a-3p ttgtgTTCAGAGcat CCUCUGAA m7b Disrupted HHFKP_110038_cluster-17142_6_16
hsa-miR-301a-5p ttgtgtTCAGAGCat GCUCUGAC m7a Disrupted HHFKP_110038_cluster-17142_6_16
hsa-miR-301b-5p ttgtgtTCAGAGCat GCUCUGAC m7a Disrupted HHFKP_110038_cluster-17142_6_16
hsa-miR-3194-3p ttgtgttCAGAGCat AGCUCUGC m6b Disrupted HHFKP_110038_cluster-17142_6_16
hsa-miR-4539 ttgtGTTCAGagcat GCUGAACU m6b Disrupted HHFKP_110038_cluster-17142_6_16
hsa-miR-520f-5p ttgtgTTTAGAGcat CCUCUAAA m7b Created HHFKP_110038_cluster-17142_6_16
hsa-miR-5691 ttgtgttCAGAGCAt UUGCUCUG m7b Disrupted HHFKP_110038_cluster-17142_6_16
hsa-miR-6502-5p ttgtgttTAGAGCat AGCUCUAG m6b Created HHFKP_110038_cluster-17142_6_16
hsa-miR-6805-3p ttgtgttCAGAGCAt UUGCUCUG m7b Disrupted HHFKP_110038_cluster-17142_6_16

Mutation Mutation ID Sample Name Cancer Type
chr4:g.56999691T>C COSM4125330 TCGA-BR-8487-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1272 cCATCATCattgtgt GAUGAUGA m7a Created HHFKP_110038_cluster-17142_6_16
hsa-miR-1322 cCATCATCattgtgt GAUGAUGC m7a Created HHFKP_110038_cluster-17142_6_16

Mutation Mutation ID Sample Name Cancer Type
chr4:g.56999677G>T COSM1056367 TCGA-B5-A0JY-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-137 caAGCAATAAgttcc UUAUUGCU m8a Created HHFKP_110038_cluster-17142_6_16

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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