SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_000321
Gene Symbol: RB1
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr13:g.48463810AG>A COSM318377 134430 [lung][NS][carcinoma][small_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3149 gCATACAAggatcttc UUUGUAUG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-3156-5p gcatacaAGATCTTc AAAGAUCU m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-362-5p gcataCAAGGATcttc AAUCCUUG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-500b-5p gcataCAAGGATcttc AAUCCUUG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-643 gcATACAAGgatcttc ACUUGUAU m7b (m7b->m6b) HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-7161-3p gcatacAAGATCTtc UAGAUCUU m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947

Mutation Mutation ID Sample Name Cancer Type
chr13:g.48463808C>A COSM95653 86501 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-297 cagCATACAaggatc AUGUAUGU m6b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-3149 cagCATACAAggatc UUUGUAUG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-362-5p cagcataCAAGGATc AAUCCUUG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-491-3p caGCATAAaaggatc CUUAUGCA m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-500b-5p cagcataCAAGGATc AAUCCUUG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-501-5p cagcataAAAGGATc AAUCCUUU m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-643 cagcATACAAGgatc ACUUGUAU m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-675-3p caGCATACAaggatc CUGUAUGC m7b (m7b->m6b) HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947

Mutation Mutation ID Sample Name Cancer Type
chr13:g.48463807A>G COSM1367313 TCGA-G4-6293-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1915-5p acagcatGCAAGGat ACCUUGCC m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-297 acagCATACAaggat AUGUAUGU m6b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-3149 acagCATACAAggat UUUGUAUG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-5011-3p acagCATGCAaggat GUGCAUGG m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-502-5p acagcatGCAAGGAt AUCCUUGC m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-643 acagcATACAAGgat ACUUGUAU m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-675-3p acaGCATACAaggat CUGUAUGC m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-6841-3p acagcaTGCAAGGat ACCUUGCA m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-1915-5p acagcatGCAAGGat ACCUUGCC m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-297 acagCATACAaggat AUGUAUGU m6b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-3149 acagCATACAAggat UUUGUAUG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-5011-3p acagCATGCAaggat GUGCAUGG m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-502-5p acagcatGCAAGGAt AUCCUUGC m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-643 acagcATACAAGgat ACUUGUAU m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-675-3p acaGCATACAaggat CUGUAUGC m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-6841-3p acagcaTGCAAGGat ACCUUGCA m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947

Mutation Mutation ID Sample Name Cancer Type
chr13:g.48463806T>C COSM1367311 TCGA-CM-6171-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-147a aacagCACACAagga GUGUGUGG m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-297 aacagCATACAagga AUGUAUGU m6b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-3149 aacagCATACAAgga UUUGUAUG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-4728-3p aaCAGCATacaagga CAUGCUGA m6b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-581 aacagcACACAAGga UCUUGUGU m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-643 aacagcATACAAGga ACUUGUAU m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-675-3p aacaGCATACAagga CUGUAUGC m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-147a aacagCACACAagga GUGUGUGG m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-297 aacagCATACAagga AUGUAUGU m6b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-3149 aacagCATACAAgga UUUGUAUG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-4728-3p aaCAGCATacaagga CAUGCUGA m6b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-581 aacagcACACAAGga UCUUGUGU m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-643 aacagcATACAAGga ACUUGUAU m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-675-3p aacaGCATACAagga CUGUAUGC m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
Mutation Mutation ID Sample Name Cancer Type
chr13:g.48463797G>GN COSM392224 LUAD-RT-S01770 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr13:g.48463795T>A COSM1756817 B47 [ovary][NS][low_malignant_potential_(borderline)_tumour][mucinous]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-580-5p aaAATCATTgtaaca UAAUGAUU m7b (m7b->m6b) HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-580-5p aaAATCATTgtaaca UAAUGAUU m7b (m7b->m6b) HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947

Mutation Mutation ID Sample Name Cancer Type
chr13:g.48463793C>A COSM947800 TCGA-B5-A11E-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-580-5p tcaaAATCATTgtaa UAAUGAUU m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-7849-3p tcaaaatAATTGTaa GACAAUUG m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-944 tcaaAATAATTgtaa AAAUUAUU m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-580-5p tcaaAATCATTgtaa UAAUGAUU m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-7849-3p tcaaaatAATTGTaa GACAAUUG m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-944 tcaaAATAATTgtaa AAAUUAUU m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947

Mutation Mutation ID Sample Name Cancer Type
chr13:g.48463784A>AT COSM920 S83100 [lung][NS][carcinoma][small_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-183-3p accttaAATTCAaaa GUGAAUUA m6b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-203a-3p accttaaATTTCAaaa GUGAAAUG m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-3606-3p accttAAATTTcaaaa AAAAUUUC m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-4452 accttaAATTCAAaa UUGAAUUC m7a Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-513a-3p accttAAATTTcaaaa UAAAUUUC m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-513c-3p accttAAATTTcaaaa UAAAUUUC m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-7856-5p aCCTTAAAttcaaaa UUUUAAGG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947

Mutation Mutation ID Sample Name Cancer Type
chr13:g.48463782A>T COSM889 S82769 [eye][retina][retinoblastoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-183-3p agaccttTAATTCAa GUGAAUUA m7b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-3974 aGACCTTTaattcaa AAAGGUCA m7a Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-4477b agaCCTTAAattcaa AUUAAGGA m6b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-548m agACCTTTaattcaa CAAAGGUA m6b Created HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947
hsa-miR-7856-5p agaCCTTAAAttcaa UUUUAAGG m7b Disrupted HHKTA_44972_NM_000321|2324|2363|1.64418175996677|0.39239120490947

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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