SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

Transcript ID:	NM_000077
Gene Symbol:	CDKN2A
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Somatic mutations that impact miRNA target sites

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974832G>A		COSM13814	933163	[biliary_tract][gallbladder][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-642b-5p	gcgGGGAACagcatg	GGUUCCCU	m6b	Created	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-7106-3p	gcgGGGAGCagcatg	AGCUCCCU	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974829G>AGCAG		COSM13975	934616	[oesophagus][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-5581-3p	gggagcaGCATGGAg	UUCCAUGC	m7b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6872-3p	gggagcaGCATGGag	CCCAUGCC	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974829G>A		COSM13230	916515	[upper_aerodigestive_tract][head_neck][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-4716-5p	gggagcAACATGGAg	UCCAUGUU	m8a	Created	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-5581-3p	gggagcaGCATGGAg	UUCCAUGC	m7b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6872-3p	gggagcaGCATGGag	CCCAUGCC	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974824G>T		COSM1737922	2080670	[upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-221-3p	cagcATGTAGCcggc	AGCUACAU	m7b	Created	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-222-3p	cagcATGTAGCcggc	AGCUACAU	m7b	Created	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-5581-3p	caGCATGGAgccggc	UUCCAUGC	m7b	(m7b->m6b)	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6872-3p	caGCATGGagccggc	CCCAUGCC	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974824G>A		COSM13691	RM	[skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-5581-3p	caGCATGGAgccggc	UUCCAUGC	m7b	(m7b->m6b)	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6872-3p	caGCATGGagccggc	CCCAUGCC	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974823GA>A		COSM5003502	PDA_100	[pancreas][NS][carcinoma][ductal_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-5581-3p	caGCATGGAgccggcg	UUCCAUGC	m7b	(m7b->m6b)	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6847-3p	cagCATGAGCCggcg	GGCUCAUG	m8a	Created	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6872-3p	caGCATGGagccggcg	CCCAUGCC	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-5581-3p	caGCATGGAgccggcg	UUCCAUGC	m7b	(m7b->m6b)	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6847-3p	cagCATGAGCCggcg	GGCUCAUG	m8a	Created	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6872-3p	caGCATGGagccggcg	CCCAUGCC	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-5581-3p	caGCATGGAgccggcg	UUCCAUGC	m7b	(m7b->m6b)	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6847-3p	cagCATGAGCCggcg	GGCUCAUG	m8a	Created	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6872-3p	caGCATGGagccggcg	CCCAUGCC	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974818G>T		COSM13255	917760	[skin][NS][malignant_melanoma][vertical_growth_phase]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974818G>A		COSM13629	HC21N	[liver][NS][other][normal]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974816G>A		COSM13257	917761	[skin][NS][malignant_melanoma][vertical_growth_phase]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-4258	agccggcGGCGGGGa	CCCCGCCA	m7a	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974815G>A		COSM12742	933238	[pancreas][ampulla_of_Vater][carcinoma][ductal_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-1181	gccGGCGACGGggag	CCGUCGCC	m8a	Created	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-4258	gccggcGGCGGGGag	CCCCGCCA	m7a	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974812G>T		COSN503823
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-4258	ggcGGCGGGGagcag	CCCCGCCA	m7a	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-7106-3p	ggcggcgGGGAGCag	AGCUCCCU	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974810G>C		COSM13639	926775	[soft_tissue][fibrous_tissue_and_uncertain_origin][gastrointestinal_stromal_tumour][spindle]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-4258	cGGCGGGGagcagca	CCCCGCCA	m7a	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-4707-3p	cGGCGGGCagcagca	AGCCCGCC	m7b	Created	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-7106-3p	cggcgGGGAGCagca	AGCUCCCU	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974805AG>G		COSM12549	902485	[oesophagus][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-5581-3p	ggggagcGCATGGAg	UUCCAUGC	m7b	Created	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

Mutation		Mutation ID	Sample Name	Cancer Type
chr9:g.21974803A>TGA		COSM13824	MDH-Panc	[pancreas][NS][carcinoma][ductal_carcinoma]
miRNA Targets Table
miR ID	miRSite	miRSeed	SeedClass	FuncClass	Cluster ID
hsa-miR-5581-3p	gagcaGCATGGAgcc	UUCCAUGC	m7b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975
hsa-miR-6872-3p	gagcaGCATGGagcc	CCCAUGCC	m6b	Disrupted	HHKTA_50244_NM_058197|198|237|1.34130617260447|6.39792486564975

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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