SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_000019
Gene Symbol: ACAT1
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr11:g.108146338T>C COSM265950 TCGA-AA-3672-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4660 gGAGCTGCttctctg UGCAGCUC m7b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-646 ggAGCTGCTTctctg AAGCAGCU m8a Created HHRBL_2975_BCBL1-2of3-SCL_6873

Mutation Mutation ID Sample Name Cancer Type
chr11:g.108146332G>C COSM1746015 B98-Tumor [urinary_tract][bladder][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4268 aatgGAGGAGCtgtt GGCUCCUC m7b Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-4691-5p aaTGGAGGAgctgtt GUCCUCCA m7b (m7b->m6b) HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-6736-3p aatggaGGAGCTGtt UCAGCUCC m7b Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-6792-3p aaTGGAGGAGctgtt CUCCUCCA m8a Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873

Mutation Mutation ID Sample Name Cancer Type
chr11:g.108146326A>C COSM1474974 TCGA-AR-A256-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-136-5p aatatcAATGGAGga ACUCCAUU m7b Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-199a-5p aatatCACTGGagga CCCAGUGU m6b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-199b-5p aatatCACTGGagga CCCAGUGU m6b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-3689a-5p aATATCACtggagga UGUGAUAU m7b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-3689b-5p aATATCACtggagga UGUGAUAU m7b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-3689e aATATCACtggagga UGUGAUAU m7b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-3689f aATATCACtggagga UGUGAUAU m7b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-3925-3p aatatcACTGGAGga ACUCCAGU m7b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-5190 aataTCACTGGagga CCAGUGAC m7a Created HHRBL_2975_BCBL1-2of3-SCL_6873

Mutation Mutation ID Sample Name Cancer Type
chr11:g.108146287T>C COSM4017594 TCGA-CG-5721-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-33a-3p gcAAACATTaaaatg CAAUGUUU m7b (m7b->m6b) HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-3591-5p gcaaACACTAAAatg UUUAGUGU m8a Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-409-3p gcaAACATTaaaatg GAAUGUUG m6b Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-4255 gcaAACACTaaaatg CAGUGUUC m6b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-4307 gcAAACATTaaaatg AAUGUUUU m7a (m7a->m6a) HHRBL_2975_BCBL1-2of3-SCL_6873

Mutation Mutation ID Sample Name Cancer Type
chr11:g.108146280G>A COSM4017593 TCGA-HU-A4GN-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-449c-3p tgtACTAGCAAacat UUGCUAGU m8a Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-8068 tgtactAACAAACAt UGUUUGUU m8a Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-8086 tgtACTAGCAaacat UGCUAGUC m7a Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873

Mutation Mutation ID Sample Name Cancer Type
chr11:g.108146265A>T COSM4840063 TCGA-FU-A3HZ-01 [cervix][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4509 agCCTTTAGTctggt ACUAAAGG m8a Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873

Mutation Mutation ID Sample Name Cancer Type
chr11:g.108146264T>C COSM1506649 TCGA-55-6968-01 [lung][right_lower_lobe][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4484 aaGCCTTTagtctgg AAAAGGCG m6b Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-4494 aagccttCAGTCTGg CCAGACUG m7b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-4499 aagcctTCAGTCTgg AAGACUGA m7b Created HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-4509 aagCCTTTAGTctgg ACUAAAGG m8a Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-6126 aaGCCTTCAgtctgg GUGAAGGC m7b (m6b->m7b) HHRBL_2975_BCBL1-2of3-SCL_6873
hsa-miR-6768-3p aaGCCTTTagtctgg CAAAGGCC m6b Disrupted HHRBL_2975_BCBL1-2of3-SCL_6873

Mutation Mutation ID Sample Name Cancer Type
chr11:g.108140121C>T COSM922671 TCGA-D1-A17K-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4793-5p aaCAGGATGcttatg ACAUCCUG m7b (m6b->m7b) HHRBL_2974_BCBL1-2of3-SCL_6105

Mutation Mutation ID Sample Name Cancer Type
chr11:g.108140117A>G COSM4935064 TCGA-DD-A4ND-01 [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1266-3p aatGAACAGGacgct CCCUGUUC m7b Disrupted HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-26b-3p aatGAACAGGacgct CCUGUUCU m7a Disrupted HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-6853-3p AATGAACAggacgct UGUUCAUU m8a Disrupted HHRBL_2974_BCBL1-2of3-SCL_6105

Mutation Mutation ID Sample Name Cancer Type
chr11:g.108140108G>A COSM1350701 Patient_1:_pre-everolimus [thyroid][NS][carcinoma][anaplastic_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1250-3p attgcacAAAATGaa ACAUUUUC m6b Created HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-153-5p attgcacAAAATGAa UCAUUUUU m7a Created HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-2113 attGCACAAAatgaa AUUUGUGC m7b Created HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-4536-3p atTGCACGAaatgaa UCGUGCAU m7a (m7a->m6a) HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-517a-3p atTGCACGAaatgaa AUCGUGCA m7b (m7b->m6b) HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-517b-3p atTGCACGAaatgaa AUCGUGCA m7b (m7b->m6b) HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-517c-3p atTGCACGAaatgaa AUCGUGCA m7b (m7b->m6b) HHRBL_2974_BCBL1-2of3-SCL_6105

Mutation Mutation ID Sample Name Cancer Type
chr11:g.108140107C>T COSM1350700 TCGA-G4-6588-01 [large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4536-3p tatTGCACGAaatga UCGUGCAU m7a Disrupted HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-517a-3p tatTGCACGAaatga AUCGUGCA m7b Disrupted HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-517b-3p tatTGCACGAaatga AUCGUGCA m7b Disrupted HHRBL_2974_BCBL1-2of3-SCL_6105
hsa-miR-517c-3p tatTGCACGAaatga AUCGUGCA m7b Disrupted HHRBL_2974_BCBL1-2of3-SCL_6105

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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