SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_003286
Gene Symbol: TOP1
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr20:g.41081221G>T COSM1026783 TCGA-D1-A16X-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-627-3p aAGAAAAGAaaacta UCUUUUCU m8a (m8a->m7a) HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187

Mutation Mutation ID Sample Name Cancer Type
chr20:g.41081216G>T COSM3423644 TCGA-F5-6814-01 [large_intestine][rectum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4659a-3p aggAGAAGAAAagaa UUUCUUCU m8a Disrupted HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-4659b-3p aggAGAAGAAAagaa UUUCUUCU m8a Disrupted HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-627-3p aggagaAGAAAAGAa UCUUUUCU m8a Disrupted HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-6875-3p aggaGAAGAAaagaa AUUCUUCC m6b Disrupted HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-942-5p agGAGAAGAaaagaa UCUUCUCU m7a (m7a->m6a) HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187

Mutation Mutation ID Sample Name Cancer Type
chr20:g.41081216G>A COSM4735303 T3145 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4659a-3p aggAGAAGAAAagaa UUUCUUCU m8a Disrupted HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-4659b-3p aggAGAAGAAAagaa UUUCUUCU m8a Disrupted HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-627-3p aggagaAGAAAAGAa UCUUUUCU m8a Disrupted HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-6875-3p aggaGAAGAAaagaa AUUCUUCC m6b Disrupted HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-942-5p agGAGAAGAaaagaa UCUUCUCU m7a (m7a->m6a) HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187

Mutation Mutation ID Sample Name Cancer Type
chr20:g.41081197A>C COSM1734451 ACINAR20 [pancreas][NS][carcinoma][acinar_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-141-5p aaaacaGAAGATacc CAUCUUCC m6b Disrupted HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-3182 aaaACAGAAGatacc GCUUCUGU m7b Disrupted HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-3692-5p aaaaCAGCAGatacc CCUGCUGG m6b Created HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-4652-3p aaAACAGAAgatacc GUUCUGUU m7b (m7b->m6b) HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-4686 aaaacAGCAGATAcc UAUCUGCU m8a Created HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-6071 aaaaCAGCAGAtacc UUCUGCUG m7b Created HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-6828-3p aaaacAGCAGATacc AUCUGCUC m7a Created HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187
hsa-miR-93-3p aaaaCAGCAGatacc ACUGCUGA m6b Created HHKTA_44982_NM_003286|711|750|1.64418175996677|1.978688146187

Mutation Mutation ID Sample Name Cancer Type
chr20:g.41076198C>G COSM723681 TCGA-66-2773-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-130b-5p agaaacaGAAAGAGa ACUCUUUC m7b Created HPSEF_13782_G16590.1_39704835
hsa-miR-4652-3p agaAACAGAAagaga GUUCUGUU m7b Created HPSEF_13782_G16590.1_39704835
hsa-miR-5010-3p agaaACACAAAgaga UUUUGUGU m7b Disrupted HPSEF_13782_G16590.1_39704835
hsa-miR-599 agaaACACAAagaga GUUGUGUC m6b Disrupted HPSEF_13782_G16590.1_39704835
hsa-miR-6844 agaaacACAAAGAga UUCUUUGU m7b Disrupted HPSEF_13782_G16590.1_39704835

Mutation Mutation ID Sample Name Cancer Type
chr20:g.41076173A>G COSM723682 TCGA-60-2723-01 [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1273g-3p taCAGTGGacataaa ACCACUGC m6b Created HPSEF_13782_G16590.1_39704835
hsa-miR-3912-5p tacagTGGACATaaa AUGUCCAU m7a Created HPSEF_13782_G16590.1_39704835
hsa-miR-4436b-5p tacAGTGGACataaa GUCCACUU m7a Created HPSEF_13782_G16590.1_39704835
hsa-miR-6509-3p taCAGTGGAcataaa UUCCACUG m7b (m6b->m7b) HPSEF_13782_G16590.1_39704835
hsa-miR-6834-3p tacagtGGACATAaa UAUGUCCC m7a Created HPSEF_13782_G16590.1_39704835

Mutation Mutation ID Sample Name Cancer Type
chr20:g.41061435C>T COSM4753301 pfg127T [stomach][NS][carcinoma][intestinal_adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1202 agaacaCTGGCACaa GUGCCAGC m7a Created HHFKP_89622_cluster-14405_5_232
hsa-miR-1227-3p agaacacTGGCACaa CGUGCCAC m6b Created HHFKP_89622_cluster-14405_5_232
hsa-miR-199a-5p agaACACTGGcacaa CCCAGUGU m7b Created HHFKP_89622_cluster-14405_5_232
hsa-miR-199b-5p agaACACTGGcacaa CCCAGUGU m7b Created HHFKP_89622_cluster-14405_5_232
hsa-miR-4255 aGAACACTGgcacaa CAGUGUUC m8a (m7a->m8a) HHFKP_89622_cluster-14405_5_232

Mutation Mutation ID Sample Name Cancer Type
chr20:g.41061426C>A COSM187471 TCGA-AA-A022-01 [large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-2117 caaagatAGAGAACa UGUUCUCU m7b Created HHFKP_89622_cluster-14405_5_232
hsa-miR-4684-5p caaagaTAGAGAaca CUCUCUAC m6b Created HHFKP_89622_cluster-14405_5_232

Mutation Mutation ID Sample Name Cancer Type
chr20:g.41061411G>T COSM1026781 TCGA-AP-A056-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-2113 aCACAAATataaaca AUUUGUGC m7a Created HHFKP_89622_cluster-14405_5_232
hsa-miR-6083 acacaaATATAAaca CUUAUAUC m6b Created HHFKP_89622_cluster-14405_5_232
hsa-miR-6844 acACAAAGAtaaaca UUCUUUGU m7b (m7b->m6b) HHFKP_89622_cluster-14405_5_232

Mutation Mutation ID Sample Name Cancer Type
chr20:g.41061410A>G COSM3939348 ESCC-123T [oesophagus][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-362-5p aacaCAAGGATaaac AAUCCUUG m7b Created HHFKP_89622_cluster-14405_5_232
hsa-miR-500b-5p aacaCAAGGATaaac AAUCCUUG m7b Created HHFKP_89622_cluster-14405_5_232
hsa-miR-5010-3p aACACAAAgataaac UUUUGUGU m7b Disrupted HHFKP_89622_cluster-14405_5_232
hsa-miR-501-5p aacacAAGGATaaac AAUCCUUU m6b Created HHFKP_89622_cluster-14405_5_232
hsa-miR-502-5p aacaCAAGGATaaac AUCCUUGC m7a Created HHFKP_89622_cluster-14405_5_232
hsa-miR-6844 aacACAAAGAtaaac UUCUUUGU m7b Disrupted HHFKP_89622_cluster-14405_5_232

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Genome Browser