SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_000963
Gene Symbol: PTGS2
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr1:g.186679164C>T COSM1473175 TCGA-E9-A22A-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-122-5p tgaaaccCACTCCAa UGGAGUGU m7a Disrupted HPSLB_748_G917.1_186648285
hsa-miR-329-5p tgAAACCTactccaa GAGGUUUU m6b Created HPSLB_748_G917.1_186648285
hsa-miR-4464 tgAAACCTactccaa AAGGUUUG m6b Created HPSLB_748_G917.1_186648285
hsa-miR-4481 tgaaaCCCACTCCaa GGAGUGGG m8a Disrupted HPSLB_748_G917.1_186648285
hsa-miR-4745-5p tgaaaCCCACTCcaa UGAGUGGG m7b Disrupted HPSLB_748_G917.1_186648285
hsa-miR-4748 tgAAACCTactccaa GAGGUUUG m6b Created HPSLB_748_G917.1_186648285
hsa-miR-504-3p tgaaaccCACTCCaa GGGAGUGC m6b Disrupted HPSLB_748_G917.1_186648285
hsa-miR-6793-5p tgaAACCCACtccaa UGUGGGUU m7b Disrupted HPSLB_748_G917.1_186648285
hsa-miR-6839-3p tgAAACCCActccaa UUGGGUUU m7b (m7b->m6b) HPSLB_748_G917.1_186648285
hsa-miR-122-5p tgaaaccCACTCCAa UGGAGUGU m7a Disrupted HPSLB_748_G917.1_186648285
hsa-miR-329-5p tgAAACCTactccaa GAGGUUUU m6b Created HPSLB_748_G917.1_186648285
hsa-miR-4464 tgAAACCTactccaa AAGGUUUG m6b Created HPSLB_748_G917.1_186648285
hsa-miR-4481 tgaaaCCCACTCCaa GGAGUGGG m8a Disrupted HPSLB_748_G917.1_186648285
hsa-miR-4745-5p tgaaaCCCACTCcaa UGAGUGGG m7b Disrupted HPSLB_748_G917.1_186648285
hsa-miR-4748 tgAAACCTactccaa GAGGUUUG m6b Created HPSLB_748_G917.1_186648285
hsa-miR-504-3p tgaaaccCACTCCaa GGGAGUGC m6b Disrupted HPSLB_748_G917.1_186648285
hsa-miR-6793-5p tgaAACCCACtccaa UGUGGGUU m7b Disrupted HPSLB_748_G917.1_186648285
hsa-miR-6839-3p tgAAACCCActccaa UUGGGUUU m7b (m7b->m6b) HPSLB_748_G917.1_186648285

Mutation Mutation ID Sample Name Cancer Type
chr1:g.186679155C>A COSM3689213 TCGA-G4-6302-01 [large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1208 ctccaaaAACAGTGc UCACUGUU m7b Created HPSLB_748_G917.1_186648285
hsa-miR-452-5p ctccaaAAACAGTgc AACUGUUU m7b Created HPSLB_748_G917.1_186648285
hsa-miR-4676-3p ctccaaAAACAGTGc CACUGUUU m8a Created HPSLB_748_G917.1_186648285
hsa-miR-6740-5p ctCCAAACacagtgc AGUUUGGG m6b Disrupted HPSLB_748_G917.1_186648285
hsa-miR-7850-5p cTCCAAACacagtgc GUUUGGAC m7a Disrupted HPSLB_748_G917.1_186648285
hsa-miR-892a ctccaaACACAGTGc CACUGUGU m8a Disrupted HPSLB_748_G917.1_186648285
hsa-miR-892c-3p ctccaaAAACAGTGc CACUGUUU m8a Created HPSLB_748_G917.1_186648285
hsa-miR-1208 ctccaaaAACAGTGc UCACUGUU m7b Created HPSLB_748_G917.1_186648285
hsa-miR-452-5p ctccaaAAACAGTgc AACUGUUU m7b Created HPSLB_748_G917.1_186648285
hsa-miR-4676-3p ctccaaAAACAGTGc CACUGUUU m8a Created HPSLB_748_G917.1_186648285
hsa-miR-6740-5p ctCCAAACacagtgc AGUUUGGG m6b Disrupted HPSLB_748_G917.1_186648285
hsa-miR-7850-5p cTCCAAACacagtgc GUUUGGAC m7a Disrupted HPSLB_748_G917.1_186648285
hsa-miR-892a ctccaaACACAGTGc CACUGUGU m8a Disrupted HPSLB_748_G917.1_186648285
hsa-miR-892c-3p ctccaaAAACAGTGc CACUGUUU m8a Created HPSLB_748_G917.1_186648285

Mutation Mutation ID Sample Name Cancer Type
chr1:g.186679131C>A COSM4802294 CHC1751T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-183-3p ttacccAATTCAagg GUGAAUUA m6b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-219a-2-3p ttaccCAATTCaagg AGAAUUGU m6b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-219b-3p ttaccCAATTCaagg AGAAUUGC m6b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-3616-5p ttaccCACTTCAagg AUGAAGUG m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-4635 ttacccaCTTCAAGg UCUUGAAG m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-4795-5p ttacCCACTTCaagg AGAAGUGG m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-573 ttaccCACTTCAagg CUGAAGUG m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-183-3p ttacccAATTCAagg GUGAAUUA m6b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-219a-2-3p ttaccCAATTCaagg AGAAUUGU m6b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-219b-3p ttaccCAATTCaagg AGAAUUGC m6b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-3616-5p ttaccCACTTCAagg AUGAAGUG m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-4635 ttacccaCTTCAAGg UCUUGAAG m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-4795-5p ttacCCACTTCaagg AGAAGUGG m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-573 ttaccCACTTCAagg CUGAAGUG m7b Disrupted HHFKP_5769_cluster-2068_18_68

Mutation Mutation ID Sample Name Cancer Type
chr1:g.186679126A>G COSM1263325 ESO-R61 [oesophagus][lower_third][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-188-5p cacttcAAGGGATtt CAUCCCUU m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-331-3p cacttCAGGGGattt GCCCCUGG m6b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-345-3p cacTTCAGGGgattt GCCCUGAA m7b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-4635 caCTTCAAGggattt UCUUGAAG m7b (m7b->m6b) HHFKP_5769_cluster-2068_18_68
hsa-miR-4780 cactTCAAGGGattt ACCCUUGA m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-573 CACTTCAGgggattt CUGAAGUG m8a Created HHFKP_5769_cluster-2068_18_68
hsa-miR-623 cacttCAAGGGATtt AUCCCUUG m8a Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-6801-3p cacttCAGGGGattt ACCCCUGC m6b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-6866-3p cacttcAAGGGATtt GAUCCCUU m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-188-5p cacttcAAGGGATtt CAUCCCUU m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-331-3p cacttCAGGGGattt GCCCCUGG m6b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-345-3p cacTTCAGGGgattt GCCCUGAA m7b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-4635 caCTTCAAGggattt UCUUGAAG m7b (m7b->m6b) HHFKP_5769_cluster-2068_18_68
hsa-miR-4780 cactTCAAGGGattt ACCCUUGA m7b Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-573 CACTTCAGgggattt CUGAAGUG m8a Created HHFKP_5769_cluster-2068_18_68
hsa-miR-623 cacttCAAGGGATtt AUCCCUUG m8a Disrupted HHFKP_5769_cluster-2068_18_68
hsa-miR-6801-3p cacttCAGGGGattt ACCCCUGC m6b Created HHFKP_5769_cluster-2068_18_68
hsa-miR-6866-3p cacttcAAGGGATtt GAUCCCUU m7b Disrupted HHFKP_5769_cluster-2068_18_68

Mutation Mutation ID Sample Name Cancer Type
chr1:g.186674267T>C COSN6012382 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4803 ccTTATGTTActtaa UAACAUAA m8a Disrupted HHFKP_5767_cluster-2068_16_20
hsa-miR-562 ccttatGCTACTTaa AAAGUAGC m7b Created HHFKP_5767_cluster-2068_16_20
hsa-miR-802 ccttaTGTTACTtaa CAGUAACA m7b Disrupted HHFKP_5767_cluster-2068_16_20

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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