SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: hsa_circ_0064822
Gene Symbol: MLH1
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr3:g.37025786TC>T COSM4448698 CSCC-40-T [skin][head_neck][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1468-3p atgcATTTTGCagcc AGCAAAAU m7b Created HHFCT_109617_cluster-15831_11_11
hsa-miR-298 atgcatTTCTGCagcc AGCAGAAG m6b Disrupted HHFCT_109617_cluster-15831_11_11
hsa-miR-3158-5p atgcattTCTGCAGcc CCUGCAGA m7b Disrupted HHFCT_109617_cluster-15831_11_11
hsa-miR-4698 atgCATTTTGcagcc UCAAAAUG m7b Created HHFCT_109617_cluster-15831_11_11
hsa-miR-548aj-5p atgcaTTTTGCAgcc UGCAAAAG m7a Created HHFCT_109617_cluster-15831_11_11
hsa-miR-548aw atgcaTTTTGCAgcc GUGCAAAA m7b Created HHFCT_109617_cluster-15831_11_11
hsa-miR-548f-5p atgcaTTTTGCAgcc UGCAAAAG m7a Created HHFCT_109617_cluster-15831_11_11
hsa-miR-548g-5p atgcaTTTTGCAgcc UGCAAAAG m7a Created HHFCT_109617_cluster-15831_11_11
hsa-miR-548x-5p atgcaTTTTGCAgcc UGCAAAAG m7a Created HHFCT_109617_cluster-15831_11_11
hsa-miR-5680 atgCATTTCTgcagcc GAGAAAUG m7b Disrupted HHFCT_109617_cluster-15831_11_11

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37025713C>A COSM4801365 CHC793T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3180-5p tctactTCTGGAAGt CUUCCAGA m8a Disrupted HPRO6_53017_G62878.1_37067206
hsa-miR-520a-5p tctactTCTGGAagt CUCCAGAG m6b Disrupted HPRO6_53017_G62878.1_37067206
hsa-miR-525-5p tctactTCTGGAagt CUCCAGAG m6b Disrupted HPRO6_53017_G62878.1_37067206
hsa-miR-587 tctactTATGGAAgt UUUCCAUA m7b Created HPRO6_53017_G62878.1_37067206

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37025701C>T COSM3915870 TCGA-FW-A3R5-06 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3974 cTGACCTTgtcttct AAAGGUCA m7b Created HPRO6_53017_G62878.1_37067206
hsa-miR-624-3p ctgACCTTGTcttct CACAAGGU m7b Created HPRO6_53017_G62878.1_37067206

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37025697A>G COSM327059 TLE50 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][acute_lymphoblastic_T_cell_leukaemia]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-6801-5p aagTCTGACCtcgtc UGGUCAGA m7b Disrupted HPRO6_53017_G62878.1_37067206

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37020380G>A COSM3940495 ESCC-003T [oesophagus][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3944-5p cCTGCACAaggagag UGUGCAGC m7a Created HHFCT_109614_cluster-15831_8_9
hsa-miR-4279 cctgcacGAGGAGAg CUCUCCUC m7b Disrupted HHFCT_109614_cluster-15831_8_9
hsa-miR-517a-3p ccTGCACGAggagag AUCGUGCA m7b (m7b->m6b) HHFCT_109614_cluster-15831_8_9
hsa-miR-517b-3p ccTGCACGAggagag AUCGUGCA m7b (m7b->m6b) HHFCT_109614_cluster-15831_8_9
hsa-miR-517c-3p ccTGCACGAggagag AUCGUGCA m7b (m7b->m6b) HHFCT_109614_cluster-15831_8_9

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37017597C>T COSM583374 TCGA-44-2662-01 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-202-3p tgTACCTCaggtaat AGAGGUAU m6b Disrupted HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-4458 tgTACCTCaggtaat AGAGGUAG m6b Disrupted HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-544b tgtaCCTCAGGTaat ACCUGAGG m8a Disrupted HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-548ag tgTACCTTaggtaat AAAGGUAA m6b Created HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-548ai tgTACCTTaggtaat AAAGGUAA m6b Created HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-548ba tgTACCTTaggtaat AAAGGUAA m6b Created HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-570-5p tgTACCTTaggtaat AAAGGUAA m6b Created HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-7162-3p tgtACCTCAGgtaat UCUGAGGU m7b Disrupted HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-202-3p tgTACCTCaggtaat AGAGGUAU m6b Disrupted HPCB1_26458_G33630.1_37059059
hsa-miR-4458 tgTACCTCaggtaat AGAGGUAG m6b Disrupted HPCB1_26458_G33630.1_37059059
hsa-miR-544b tgtaCCTCAGGTaat ACCUGAGG m8a Disrupted HPCB1_26458_G33630.1_37059059
hsa-miR-548ag tgTACCTTaggtaat AAAGGUAA m6b Created HPCB1_26458_G33630.1_37059059
hsa-miR-548ai tgTACCTTaggtaat AAAGGUAA m6b Created HPCB1_26458_G33630.1_37059059
hsa-miR-548ba tgTACCTTaggtaat AAAGGUAA m6b Created HPCB1_26458_G33630.1_37059059
hsa-miR-570-5p tgTACCTTaggtaat AAAGGUAA m6b Created HPCB1_26458_G33630.1_37059059
hsa-miR-7162-3p tgtACCTCAGgtaat UCUGAGGU m7b Disrupted HPCB1_26458_G33630.1_37059059
hsa-miR-202-3p tgTACCTCaggtaat AGAGGUAU m6b Disrupted HPCB3_15057_G20618.1_37059059
hsa-miR-4458 tgTACCTCaggtaat AGAGGUAG m6b Disrupted HPCB3_15057_G20618.1_37059059
hsa-miR-544b tgtaCCTCAGGTaat ACCUGAGG m8a Disrupted HPCB3_15057_G20618.1_37059059
hsa-miR-548ag tgTACCTTaggtaat AAAGGUAA m6b Created HPCB3_15057_G20618.1_37059059
hsa-miR-548ai tgTACCTTaggtaat AAAGGUAA m6b Created HPCB3_15057_G20618.1_37059059
hsa-miR-548ba tgTACCTTaggtaat AAAGGUAA m6b Created HPCB3_15057_G20618.1_37059059
hsa-miR-570-5p tgTACCTTaggtaat AAAGGUAA m6b Created HPCB3_15057_G20618.1_37059059
hsa-miR-7162-3p tgtACCTCAGgtaat UCUGAGGU m7b Disrupted HPCB3_15057_G20618.1_37059059

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37017587T>TT COSM330646 1773690 [large_intestine][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4506 cACCCATTTcctgtac AAAUGGGU m8a (m7a->m8a) HHFKP_101777_cluster-15831_1_102
hsa-miR-4700-3p cacccatTCCTGTac CACAGGAC m6b Disrupted HHFKP_101777_cluster-15831_1_102
hsa-miR-5093 caccCATTTCCTgtac AGGAAAUG m8a Created HHFKP_101777_cluster-15831_1_102
hsa-miR-4506 cACCCATTTcctgtac AAAUGGGU m8a (m7a->m8a) HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-4700-3p cacccatTCCTGTac CACAGGAC m6b Disrupted HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-5093 caccCATTTCCTgtac AGGAAAUG m8a Created HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-4506 cACCCATTTcctgtac AAAUGGGU m8a (m7a->m8a) HPCB1_26458_G33630.1_37059059
hsa-miR-4700-3p cacccatTCCTGTac CACAGGAC m6b Disrupted HPCB1_26458_G33630.1_37059059
hsa-miR-5093 caccCATTTCCTgtac AGGAAAUG m8a Created HPCB1_26458_G33630.1_37059059
hsa-miR-4506 cACCCATTTcctgtac AAAUGGGU m8a (m7a->m8a) HPCB3_15057_G20618.1_37059059
hsa-miR-4700-3p cacccatTCCTGTac CACAGGAC m6b Disrupted HPCB3_15057_G20618.1_37059059
hsa-miR-5093 caccCATTTCCTgtac AGGAAAUG m8a Created HPCB3_15057_G20618.1_37059059

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37017586TT>T COSM27626 1140964 [large_intestine][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-2392 acacCCATCCTgtac UAGGAUGG m7b Created HHFKP_101777_cluster-15831_1_102
hsa-miR-4506 acACCCATTcctgtac AAAUGGGU m7b (m7b->m6b) HHFKP_101777_cluster-15831_1_102
hsa-miR-2392 acacCCATCCTgtac UAGGAUGG m7b Created HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-4506 acACCCATTcctgtac AAAUGGGU m7b (m7b->m6b) HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-2392 acacCCATCCTgtac UAGGAUGG m7b Created HPCB1_26458_G33630.1_37059059
hsa-miR-4506 acACCCATTcctgtac AAAUGGGU m7b (m7b->m6b) HPCB1_26458_G33630.1_37059059
hsa-miR-2392 acacCCATCCTgtac UAGGAUGG m7b Created HPCB3_15057_G20618.1_37059059
hsa-miR-4506 acACCCATTcctgtac AAAUGGGU m7b (m7b->m6b) HPCB3_15057_G20618.1_37059059

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37017570CA>C COSM1422589 TCGA-CM-4746-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-2052 atttgccCAAAACAc UGUUUUGA m7a Created HHFCT_109611_cluster-15831_5_13
hsa-miR-2052 atttgccCAAAACAc UGUUUUGA m7a Created HHFKP_101777_cluster-15831_1_102
hsa-miR-2052 atttgccCAAAACAc UGUUUUGA m7a Created HHKTA_49635_NM_000249|1043|1082|1.38457411365623|0.753514568582325
hsa-miR-2052 atttgccCAAAACAc UGUUUUGA m7a Created HPCB1_26458_G33630.1_37059059
hsa-miR-2052 atttgccCAAAACAc UGUUUUGA m7a Created HPCB3_15057_G20618.1_37059059

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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