SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: hsa_circ_0002381
Gene Symbol: MLH1
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Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr3:g.37047555T>A COSM269592 TCGA-AA-3715-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3714 gctTGCCTTagatag GAAGGCAG m6b Disrupted HHFCT_109622_cluster-15831_16_8
hsa-miR-3910 gctTGCCTTagatag AAAGGCAU m6b Disrupted HHFCT_109622_cluster-15831_16_8
hsa-miR-4521 gcttgCCTTAGatag GCUAAGGA m6b Disrupted HHFCT_109622_cluster-15831_16_8
hsa-miR-8074 gcttGCCATAGatag CUAUGGCG m7a Created HHFCT_109622_cluster-15831_16_8

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37047550T>G COSM583371 TCGA-05-5428-01 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-124-3p gccatgcGTGCCTTa UAAGGCAC m7b Created HHFCT_109622_cluster-15831_16_8
hsa-miR-3622a-5p gccatgCGTGCCTta CAGGCACG m7b Created HHFCT_109622_cluster-15831_16_8
hsa-miR-506-3p gccatgcGTGCCTTa UAAGGCAC m7b Created HHFCT_109622_cluster-15831_16_8

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37047546A>G COSM26492 TCGA-DC-6157-01 [large_intestine][rectum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3177-3p ccttGCCGTGCttgc UGCACGGC m7b Created HHFCT_109622_cluster-15831_16_8
hsa-miR-4445-3p ccTTGCCGTGcttgc CACGGCAA m8a Created HHFCT_109622_cluster-15831_16_8
hsa-miR-548al ccTTGCCGTgcttgc AACGGCAA m7b (m6b->m7b) HHFCT_109622_cluster-15831_16_8
hsa-miR-6809-5p CCTTGCCAtgcttgc UGGCAAGG m8a Disrupted HHFCT_109622_cluster-15831_16_8

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37047531C>G COSM1159627 S33TP [stomach][NS][carcinoma][intestinal_adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1276 agcaccGCTCTTTga UAAAGAGC m7b Disrupted HHFCT_109622_cluster-15831_16_8
hsa-miR-4746-3p aGCACCGCTctttga AGCGGUGC m8a (m8a->m7a) HHFCT_109622_cluster-15831_16_8
hsa-miR-548ao-3p agcacCGGTCTTTga AAAGACCG m8a Created HHFCT_109622_cluster-15831_16_8
hsa-miR-548u agcaccgGTCTTTGa CAAAGACU m7a Created HHFCT_109622_cluster-15831_16_8
hsa-miR-583 agcaccgCTCTTTGa CAAAGAGG m7a Disrupted HHFCT_109622_cluster-15831_16_8

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37047525G>A COSM3737418 SJRHB009_D [soft_tissue][striated_muscle][rhabdomyosarcoma][alveolar]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1250-5p ggagccAGCACCGct ACGGUGCU m7b Disrupted HHFCT_109622_cluster-15831_16_8
hsa-miR-149-5p gGAGCCAGcaccgct UCUGGCUC m7b Disrupted HHFCT_109622_cluster-15831_16_8
hsa-miR-4746-3p ggagccaGCACCGCt AGCGGUGC m7b Disrupted HHFCT_109622_cluster-15831_16_8
hsa-miR-5580-5p ggAGCCAGCAccgct UGCUGGCU m8a Disrupted HHFCT_109622_cluster-15831_16_8

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37047518G>A COSM25914 1088703 [skin][leg][malignant_melanoma][nodular]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4268 cttcctAGGAGCCag GGCUCCUC m7a Disrupted HHFCT_109622_cluster-15831_16_8
hsa-miR-4448 cttcctAGGAGCCag GGCUCCUU m7a Disrupted HHFCT_109622_cluster-15831_16_8
hsa-miR-5571-3p cttCCTAGGAgccag GUCCUAGG m7b Disrupted HHFCT_109622_cluster-15831_16_8
hsa-miR-6822-3p cttcctaAGAGCCag AGGCUCUA m6b Created HHFCT_109622_cluster-15831_16_8
hsa-miR-760 cttcctaAGAGCCag CGGCUCUG m6b Created HHFCT_109622_cluster-15831_16_8
hsa-miR-8057 cttcctaAGAGCCAg GUGGCUCU m7b Created HHFCT_109622_cluster-15831_16_8

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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