SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NM_001167618
Gene Symbol: MLH1
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr3:g.37050653A>T COSM25890 80 [endometrium][NS][hyperplasia][complex]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-410-3p ggtGTTATATatggt AAUAUAAC m7b Created HHFCT_109626_cluster-15831_20_30
hsa-miR-5011-5p ggtgtTATATATggt UAUAUAUA m7b Created HHFCT_109626_cluster-15831_20_30
Mutation Mutation ID Sample Name Cancer Type
chr3:g.37050653A>G COSM1422607 TCGA-AY-6197-01 [large_intestine][caecum][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr3:g.37050651T>A COSM3823741 TCGA-A8-A09Z-01 [breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3591-3p gaGGTGTTaaatatg AAACACCA m6b Disrupted HHFCT_109626_cluster-15831_20_30

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37050642G>C COSM1309065 TCGA-GD-A2C5-01 [urinary_tract][bladder][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-146a-3p agtctTTCAGAGGtg CCUCUGAA m8a Created HHFCT_109626_cluster-15831_20_30
hsa-miR-371a-5p agtcTTTGAGaggtg ACUCAAAC m6b Disrupted HHFCT_109626_cluster-15831_20_30
hsa-miR-371b-5p agtcTTTGAGaggtg ACUCAAAA m6b Disrupted HHFCT_109626_cluster-15831_20_30
hsa-miR-372-5p agtcTTTGAGaggtg CCUCAAAU m6b Disrupted HHFCT_109626_cluster-15831_20_30
hsa-miR-373-5p agtcTTTGAGaggtg ACUCAAAA m6b Disrupted HHFCT_109626_cluster-15831_20_30
hsa-miR-4766-5p agtCTTTCAGAggtg UCUGAAAG m8a Created HHFCT_109626_cluster-15831_20_30
hsa-miR-548u AGTCTTTGagaggtg CAAAGACU m8a Disrupted HHFCT_109626_cluster-15831_20_30
hsa-miR-616-5p agtcTTTGAGaggtg ACUCAAAA m6b Disrupted HHFCT_109626_cluster-15831_20_30
hsa-miR-6800-3p agtctttGAGAGGTg CACCUCUC m7b Disrupted HHFCT_109626_cluster-15831_20_30

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37050576A>T COSM4702349 T2197 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-33a-3p gcctcctAAACATTt CAAUGUUU m7b Disrupted HHFCT_109625_cluster-15831_19_9
hsa-miR-4428 gcCTCCTTaacattt CAAGGAGA m6b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-4477b gccTCCTTAAcattt AUUAAGGA m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-4779 gCCTCCTAaacattt UAGGAGGG m7a Disrupted HHFCT_109625_cluster-15831_19_9
hsa-miR-6891-5p gCCTCCTTAacattt UAAGGAGG m8a (m7a->m8a) HHFCT_109625_cluster-15831_19_9
hsa-miR-33a-3p gcctcctAAACATTt CAAUGUUU m7b Disrupted HHFKP_101785_cluster-15831_9_97
hsa-miR-4428 gcCTCCTTaacattt CAAGGAGA m6b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-4477b gccTCCTTAAcattt AUUAAGGA m7b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-4779 gCCTCCTAaacattt UAGGAGGG m7a Disrupted HHFKP_101785_cluster-15831_9_97
hsa-miR-6891-5p gCCTCCTTAacattt UAAGGAGG m8a (m7a->m8a) HHFKP_101785_cluster-15831_9_97

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37050556G>A COSM4117131 TCGA-BR-4201-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1238-5p gccttgCACTCACac GUGAGUGG m7a Created HHFCT_109625_cluster-15831_19_9
hsa-miR-130a-3p gccTTGCACTcacac CAGUGCAA m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-130b-3p gccTTGCACTcacac CAGUGCAA m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-301a-3p gccTTGCACTcacac CAGUGCAA m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-301b-3p gccTTGCACTcacac CAGUGCAA m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-3666 gccTTGCACTcacac CAGUGCAA m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-4295 gccTTGCACTcacac CAGUGCAA m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-454-3p gccTTGCACTcacac UAGUGCAA m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-4658 gccttgCACTCACac GUGAGUGU m7a Created HHFCT_109625_cluster-15831_19_9
hsa-miR-4758-5p gccttgCACTCACac GUGAGUGG m7a Created HHFCT_109625_cluster-15831_19_9
hsa-miR-6790-5p gccttgCACTCACac GUGAGUGU m7a Created HHFCT_109625_cluster-15831_19_9
hsa-miR-1238-5p gccttgCACTCACac GUGAGUGG m7a Created HHFKP_101785_cluster-15831_9_97
hsa-miR-130a-3p gccTTGCACTcacac CAGUGCAA m7b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-130b-3p gccTTGCACTcacac CAGUGCAA m7b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-301a-3p gccTTGCACTcacac CAGUGCAA m7b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-301b-3p gccTTGCACTcacac CAGUGCAA m7b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-3666 gccTTGCACTcacac CAGUGCAA m7b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-4295 gccTTGCACTcacac CAGUGCAA m7b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-454-3p gccTTGCACTcacac UAGUGCAA m7b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-4658 gccttgCACTCACac GUGAGUGU m7a Created HHFKP_101785_cluster-15831_9_97
hsa-miR-4758-5p gccttgCACTCACac GUGAGUGG m7a Created HHFKP_101785_cluster-15831_9_97
hsa-miR-6790-5p gccttgCACTCACac GUGAGUGU m7a Created HHFKP_101785_cluster-15831_9_97

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37050554G>A COSM1422606 TCGA-CK-5912-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4708-3p aaGCCTTGCgctcac AGCAAGGC m7b (m7b->m6b) HHFCT_109625_cluster-15831_19_9
hsa-miR-4708-3p aaGCCTTGCgctcac AGCAAGGC m7b (m7b->m6b) HHFKP_101785_cluster-15831_9_97

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37050553T>G COSM51407 1445885 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-339-3p aaagcctGGCGCTCa UGAGCGCC m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-4708-3p aaaGCCTTGCgctca AGCAAGGC m7b Disrupted HHFCT_109625_cluster-15831_19_9
hsa-miR-4755-3p aaaGCCTGGCgctca AGCCAGGC m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-339-3p aaagcctGGCGCTCa UGAGCGCC m7b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-4708-3p aaaGCCTTGCgctca AGCAAGGC m7b Disrupted HHFKP_101785_cluster-15831_9_97
hsa-miR-4755-3p aaaGCCTGGCgctca AGCCAGGC m7b Created HHFKP_101785_cluster-15831_9_97

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37050552T>C COSM1422605 TCGA-AF-2693-01 [large_intestine][rectum][NS][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3158-3p taAAGCCCTgcgctc AAGGGCUU m7b (m6b->m7b) HHFCT_109625_cluster-15831_19_9
hsa-miR-4708-3p taaaGCCTTGCgctc AGCAAGGC m7b Disrupted HHFCT_109625_cluster-15831_19_9
hsa-miR-6132 taaaGCCCTGCgctc AGCAGGGC m7b Created HHFCT_109625_cluster-15831_19_9
hsa-miR-6836-5p taaaGCCCTGCGctc CGCAGGGC m8a Created HHFCT_109625_cluster-15831_19_9
hsa-miR-3158-3p taAAGCCCTgcgctc AAGGGCUU m7b (m6b->m7b) HHFKP_101785_cluster-15831_9_97
hsa-miR-4708-3p taaaGCCTTGCgctc AGCAAGGC m7b Disrupted HHFKP_101785_cluster-15831_9_97
hsa-miR-6132 taaaGCCCTGCgctc AGCAGGGC m7b Created HHFKP_101785_cluster-15831_9_97
hsa-miR-6836-5p taaaGCCCTGCGctc CGCAGGGC m8a Created HHFKP_101785_cluster-15831_9_97

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37014799A>C COSN6767172 RK196_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-3064-5p gggcataCAGCCAGc UCUGGCUG m7b Created HHRBL_9817_BCBL1-2of3-SCL_9861
hsa-miR-491-3p ggGCATAAagccagc CUUAUGCA m6b Disrupted HHRBL_9817_BCBL1-2of3-SCL_9861
hsa-miR-4999-5p gggcATACAGCcagc UGCUGUAU m7b Created HHRBL_9817_BCBL1-2of3-SCL_9861
hsa-miR-6504-5p gggcataCAGCCAGc UCUGGCUG m7b Created HHRBL_9817_BCBL1-2of3-SCL_9861
hsa-miR-675-3p ggGCATACAGccagc CUGUAUGC m8a Created HHRBL_9817_BCBL1-2of3-SCL_9861
hsa-miR-7974 gggcatACAGCCagc AGGCUGUG m6b Created HHRBL_9817_BCBL1-2of3-SCL_9861

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37014522CA>C COSM25919 1088747 [large_intestine][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4325 agAAGTGCAtcttctt UUGCACUU m7b (m7b->m6b) HHFCT_109609_cluster-15831_3_8
hsa-miR-5197-3p agaagtgCTCTTCTT AAGAAGAG m8a Created HHFCT_109609_cluster-15831_3_8

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37014516G>C COSM3774950 TCGA-FD-A3SM-01 [urinary_tract][bladder][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-412-3p caGTGAAGaagtgca ACUUCACC m6b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-4778-3p cagtGAAGAAGtgca UCUUCUUC m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-6500-3p cagtgaACAAGTGca ACACUUGU m7b Created HHFCT_109609_cluster-15831_3_8
hsa-miR-6754-3p caGTGAAGAagtgca UCUUCACC m7a (m7a->m6a) HHFCT_109609_cluster-15831_3_8
hsa-miR-6837-3p cAGTGAAGaagtgca CCUUCACU m7b Disrupted HHFCT_109609_cluster-15831_3_8

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37014509C>T COSM1422587 TCGA-AA-3697-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1244 AACTACTTagtgaag AAGUAGUU m8a Created HHFCT_109609_cluster-15831_3_8
hsa-miR-181b-2-3p aactacTCAGTGAag CUCACUGA m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-181b-3p aactacTCAGTGAag CUCACUGA m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-4420 aactacTCAGTGAag GUCACUGA m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-562 aaCTACTTagtgaag AAAGUAGC m6b Created HHFCT_109609_cluster-15831_3_8
hsa-miR-6869-5p aaCTACTCAgtgaag GUGAGUAG m7b (m7b->m6b) HHFCT_109609_cluster-15831_3_8

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37014509C>G COSM1309064 TCGA-FD-A3B6-01 [urinary_tract][bladder][carcinoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-181b-2-3p aactacTCAGTGAag CUCACUGA m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-181b-3p aactacTCAGTGAag CUCACUGA m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-199a-3p aACTACTGagtgaag ACAGUAGU m7b Created HHFCT_109609_cluster-15831_3_8
hsa-miR-199b-3p aACTACTGagtgaag ACAGUAGU m7b Created HHFCT_109609_cluster-15831_3_8
hsa-miR-222-5p aaCTACTGAGtgaag CUCAGUAG m8a Created HHFCT_109609_cluster-15831_3_8
hsa-miR-3129-5p aACTACTGagtgaag GCAGUAGU m7b Created HHFCT_109609_cluster-15831_3_8
hsa-miR-4420 aactacTCAGTGAag GUCACUGA m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-4797-3p aacTACTGAGtgaag UCUCAGUA m7b Created HHFCT_109609_cluster-15831_3_8
hsa-miR-512-5p aactaCTGAGTGaag CACUCAGC m7a Created HHFCT_109609_cluster-15831_3_8
hsa-miR-6794-3p aactactGAGTGAag CUCACUCU m6b Created HHFCT_109609_cluster-15831_3_8
hsa-miR-6869-5p aaCTACTCAgtgaag GUGAGUAG m7b (m7b->m6b) HHFCT_109609_cluster-15831_3_8
hsa-miR-936 aaCTACTGagtgaag ACAGUAGA m6b Created HHFCT_109609_cluster-15831_3_8

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37014509C>A COSM26798 TCGA-G4-6293-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-181b-2-3p aactacTCAGTGAag CUCACUGA m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-181b-3p aactacTCAGTGAag CUCACUGA m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-374c-3p aactaCTAAGTGaag CACUUAGC m7a Created HHFCT_109609_cluster-15831_3_8
hsa-miR-4420 aactacTCAGTGAag GUCACUGA m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-6869-5p aaCTACTCAgtgaag GUGAGUAG m7b (m7b->m6b) HHFCT_109609_cluster-15831_3_8

Mutation Mutation ID Sample Name Cancer Type
chr3:g.37014495C>T COSM3593043 TCGA-EB-A5UM-01 [skin][NS][malignant_melanoma][NS]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-1261 acaTATCCAatgcaa AUGGAUAA m6b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-33a-5p acatatcCAATGCAa GUGCAUUG m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-33b-5p acatatcCAATGCAa GUGCAUUG m7b Disrupted HHFCT_109609_cluster-15831_3_8
hsa-miR-4791 aCATATCCAatgcaa UGGAUAUG m8a (m8a->m7a) HHFCT_109609_cluster-15831_3_8

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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