SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
Transcript ID: NR_111983
Gene Symbol: CASP8
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr2:g.201286593G>C COSM2907183 BB49-SCCHN [upper_aerodigestive_tract][mouth][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-15b-3p tcTGATTCatggtgc CGAAUCAU m6b Created HPSEF_12583_G15142.1_202151315

Mutation Mutation ID Sample Name Cancer Type
chr2:g.201286581T>C COSM3355728 2122577 [stomach][NS][carcinoma][diffuse_adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-7515 cttgtctTCCCTTCt AGAAGGGA m7b Disrupted HPSLC_10820_G12783.1_202151282
hsa-miR-7-5p cttGTCTTCCcttct UGGAAGAC m7b Disrupted HPSLC_10820_G12783.1_202151282
hsa-miR-9500 cttgtCTTCCCTTct AAGGGAAG m8a Disrupted HPSLC_10820_G12783.1_202151282
hsa-miR-3175 cttgTCTCCCCttct CGGGGAGA m7b Created HPTK7_4361_G6356.1_202151290
hsa-miR-3179 cttgtctCCCCTTCt AGAAGGGG m7b Created HPTK7_4361_G6356.1_202151290
hsa-miR-7515 cttgtctTCCCTTCt AGAAGGGA m7b Disrupted HPTK7_4361_G6356.1_202151290
hsa-miR-7-5p cttGTCTTCCcttct UGGAAGAC m7b Disrupted HPTK7_4361_G6356.1_202151290
hsa-miR-9500 cttgtCTTCCCTTct AAGGGAAG m8a Disrupted HPTK7_4361_G6356.1_202151290
hsa-miR-3175 cttgTCTCCCCttct CGGGGAGA m7b Created HHFKP_85240_cluster-13317_8_212
hsa-miR-3179 cttgtctCCCCTTCt AGAAGGGG m7b Created HHFKP_85240_cluster-13317_8_212
hsa-miR-7515 cttgtctTCCCTTCt AGAAGGGA m7b Disrupted HHFKP_85240_cluster-13317_8_212
hsa-miR-7-5p cttGTCTTCCcttct UGGAAGAC m7b Disrupted HHFKP_85240_cluster-13317_8_212
hsa-miR-9500 cttgtCTTCCCTTct AAGGGAAG m8a Disrupted HHFKP_85240_cluster-13317_8_212
hsa-miR-3175 cttgTCTCCCCttct CGGGGAGA m7b Created HHKTA_39369_NM_001080125|1774|1813|1.94705734732907|0.213135062634412
hsa-miR-3179 cttgtctCCCCTTCt AGAAGGGG m7b Created HHKTA_39369_NM_001080125|1774|1813|1.94705734732907|0.213135062634412
hsa-miR-7515 cttgtctTCCCTTCt AGAAGGGA m7b Disrupted HHKTA_39369_NM_001080125|1774|1813|1.94705734732907|0.213135062634412
hsa-miR-7-5p cttGTCTTCCcttct UGGAAGAC m7b Disrupted HHKTA_39369_NM_001080125|1774|1813|1.94705734732907|0.213135062634412
hsa-miR-9500 cttgtCTTCCCTTct AAGGGAAG m8a Disrupted HHKTA_39369_NM_001080125|1774|1813|1.94705734732907|0.213135062634412
hsa-miR-3175 cttgTCTCCCCttct CGGGGAGA m7b Created HPCB1_22409_G28298.1_202151296
hsa-miR-3179 cttgtctCCCCTTCt AGAAGGGG m7b Created HPCB1_22409_G28298.1_202151296
hsa-miR-7515 cttgtctTCCCTTCt AGAAGGGA m7b Disrupted HPCB1_22409_G28298.1_202151296
hsa-miR-7-5p cttGTCTTCCcttct UGGAAGAC m7b Disrupted HPCB1_22409_G28298.1_202151296
hsa-miR-9500 cttgtCTTCCCTTct AAGGGAAG m8a Disrupted HPCB1_22409_G28298.1_202151296
hsa-miR-3175 cttgTCTCCCCttct CGGGGAGA m7b Created HPCB3_12737_G17318.1_202151296
hsa-miR-3179 cttgtctCCCCTTCt AGAAGGGG m7b Created HPCB3_12737_G17318.1_202151296
hsa-miR-7515 cttgtctTCCCTTCt AGAAGGGA m7b Disrupted HPCB3_12737_G17318.1_202151296
hsa-miR-7-5p cttGTCTTCCcttct UGGAAGAC m7b Disrupted HPCB3_12737_G17318.1_202151296
hsa-miR-9500 cttgtCTTCCCTTct AAGGGAAG m8a Disrupted HPCB3_12737_G17318.1_202151296
hsa-miR-3175 cttgTCTCCCCttct CGGGGAGA m7b Created HPKTA_35204_G37827.1_202151296
hsa-miR-3179 cttgtctCCCCTTCt AGAAGGGG m7b Created HPKTA_35204_G37827.1_202151296
hsa-miR-7515 cttgtctTCCCTTCt AGAAGGGA m7b Disrupted HPKTA_35204_G37827.1_202151296
hsa-miR-7-5p cttGTCTTCCcttct UGGAAGAC m7b Disrupted HPKTA_35204_G37827.1_202151296
hsa-miR-9500 cttgtCTTCCCTTct AAGGGAAG m8a Disrupted HPKTA_35204_G37827.1_202151296
hsa-miR-3175 cttgTCTCCCCttct CGGGGAGA m7b Created HPSEF_12583_G15142.1_202151315
hsa-miR-3179 cttgtctCCCCTTCt AGAAGGGG m7b Created HPSEF_12583_G15142.1_202151315
hsa-miR-7515 cttgtctTCCCTTCt AGAAGGGA m7b Disrupted HPSEF_12583_G15142.1_202151315
hsa-miR-7-5p cttGTCTTCCcttct UGGAAGAC m7b Disrupted HPSEF_12583_G15142.1_202151315
hsa-miR-9500 cttgtCTTCCCTTct AAGGGAAG m8a Disrupted HPSEF_12583_G15142.1_202151315
hsa-miR-3175 cttgTCTCCCCttct CGGGGAGA m7b Created HPSLC_10820_G12783.1_202151282
hsa-miR-3179 cttgtctCCCCTTCt AGAAGGGG m7b Created HPSLC_10820_G12783.1_202151282
Mutation Mutation ID Sample Name Cancer Type
chr2:g.201286566GA>G COSM3686184 P134 [central_nervous_system][brain][glioma][astrocytoma_Grade_IV]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr2:g.201286547C>T COSM3713596 TCGA-IR-A3LL-01 [cervix][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-7160-5p gatgCCTCAGCctac UGCUGAGG m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-3929 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4419b gatgccTCAGCCTac GAGGCUGA m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4478 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4649-3p gatGCCTCAGcctac UCUGAGGC m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-7160-5p gatgCCTCAGCctac UGCUGAGG m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-3929 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-4419b gatgccTCAGCCTac GAGGCUGA m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-4478 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-4649-3p gatGCCTCAGcctac UCUGAGGC m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-7160-5p gatgCCTCAGCctac UGCUGAGG m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-3929 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4419b gatgccTCAGCCTac GAGGCUGA m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4478 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4649-3p gatGCCTCAGcctac UCUGAGGC m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-7160-5p gatgCCTCAGCctac UGCUGAGG m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-3929 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-4419b gatgccTCAGCCTac GAGGCUGA m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-4478 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-4649-3p gatGCCTCAGcctac UCUGAGGC m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-7160-5p gatgCCTCAGCctac UGCUGAGG m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-3929 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4419b gatgccTCAGCCTac GAGGCUGA m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4478 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4649-3p gatGCCTCAGcctac UCUGAGGC m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-7160-5p gatgCCTCAGCctac UGCUGAGG m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-3929 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-4419b gatgccTCAGCCTac GAGGCUGA m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-4478 gatgccTCAGCCTac GAGGCUGA m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-4649-3p gatGCCTCAGcctac UCUGAGGC m7b Disrupted HPCB3_12736_G17317.1_202151280

Mutation Mutation ID Sample Name Cancer Type
chr2:g.201286543G>C COSM4090194 TCGA-D7-8570-01 [stomach][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4649-3p aacagatGCCTCAGc UCUGAGGC m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-6834-5p aacagaTCCCTCAgc GUGAGGGA m7b Created HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4649-3p aacagatGCCTCAGc UCUGAGGC m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-6834-5p aacagaTCCCTCAgc GUGAGGGA m7b Created HPCB3_12736_G17317.1_202151280
hsa-miR-4649-3p aacagatGCCTCAGc UCUGAGGC m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-6834-5p aacagaTCCCTCAgc GUGAGGGA m7b Created HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4649-3p aacagatGCCTCAGc UCUGAGGC m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-6834-5p aacagaTCCCTCAgc GUGAGGGA m7b Created HPCB3_12736_G17317.1_202151280
hsa-miR-4649-3p aacagatGCCTCAGc UCUGAGGC m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-6834-5p aacagaTCCCTCAgc GUGAGGGA m7b Created HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4649-3p aacagatGCCTCAGc UCUGAGGC m7b Disrupted HPCB3_12736_G17317.1_202151280
hsa-miR-6834-5p aacagaTCCCTCAgc GUGAGGGA m7b Created HPCB3_12736_G17317.1_202151280

Mutation Mutation ID Sample Name Cancer Type
chr2:g.201286534G>GG COSM3355736 2122356 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-2355-5p acaTGGGGAaacaga AUCCCCAG m6b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-361-3p acaTGGGGGAaacaga UCCCCCAG m7a Created HHFKP_85239_cluster-13317_7_43
hsa-miR-3679-3p acatGGGGGAAacaga CUUCCCCC m7b Created HHFKP_85239_cluster-13317_7_43
hsa-miR-2355-5p acaTGGGGAaacaga AUCCCCAG m6b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-361-3p acaTGGGGGAaacaga UCCCCCAG m7a Created HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-3679-3p acatGGGGGAAacaga CUUCCCCC m7b Created HHRBL_8777_BCBL1-2of3-SCL_10651

Mutation Mutation ID Sample Name Cancer Type
chr2:g.201286530T>TG COSM272234 TCGA-AA-3947-01 [large_intestine][colon][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-2355-5p aaaaacaTGGGGAaa AUCCCCAG m6b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-361-3p aaaaacaTGGGGGAaa UCCCCCAG m7a Created HHFKP_85239_cluster-13317_7_43
hsa-miR-4307 aAAAACATggggaaa AAUGUUUU m7b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-4716-5p aaaAACATGGggaaa UCCAUGUU m7b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-2355-5p aaaaacaTGGGGAaa AUCCCCAG m6b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-361-3p aaaaacaTGGGGGAaa UCCCCCAG m7a Created HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4307 aAAAACATggggaaa AAUGUUUU m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4716-5p aaaAACATGGggaaa UCCAUGUU m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-2355-5p aaaaacaTGGGGAaa AUCCCCAG m6b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-361-3p aaaaacaTGGGGGAaa UCCCCCAG m7a Created HHFKP_85239_cluster-13317_7_43
hsa-miR-4307 aAAAACATggggaaa AAUGUUUU m7b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-4716-5p aaaAACATGGggaaa UCCAUGUU m7b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-2355-5p aaaaacaTGGGGAaa AUCCCCAG m6b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-361-3p aaaaacaTGGGGGAaa UCCCCCAG m7a Created HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4307 aAAAACATggggaaa AAUGUUUU m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4716-5p aaaAACATGGggaaa UCCAUGUU m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651

Mutation Mutation ID Sample Name Cancer Type
chr2:g.201286527A>T COSM364535 LUAD-E00897 [lung][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite miRSeed SeedClass FuncClass Cluster ID
hsa-miR-4307 aagaAAAACATgggg AAUGUUUU m7b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-4716-5p aagaaaAACATGGgg UCCAUGUU m7b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-4307 aagaAAAACATgggg AAUGUUUU m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4716-5p aagaaaAACATGGgg UCCAUGUU m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4307 aagaAAAACATgggg AAUGUUUU m7b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-4716-5p aagaaaAACATGGgg UCCAUGUU m7b Disrupted HHFKP_85239_cluster-13317_7_43
hsa-miR-4307 aagaAAAACATgggg AAUGUUUU m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651
hsa-miR-4716-5p aagaaaAACATGGgg UCCAUGUU m7b Disrupted HHRBL_8777_BCBL1-2of3-SCL_10651

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

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