SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_144625
Gene Symbol:	WDR64
Description:	Homo sapiens WD repeat domain 64 (WDR64), mRNA.
Gene Location:	chr1(+):241815579-241965434
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.241801644A>T			COSN15539319		AOCS-064-1-6		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-5580-3p	aaaaagaaATATGTaccag	0	CACAUAUG	m6b	Created	no TS	0.014000	-4.460000
hsa-miR-5580-3p	aaaaagaaATATGTaccag	0	CACAUAUG	m6b	Created	no TS	0.014000	-4.460000

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.241801780C>T			COSN14514940		8067938		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4659a-5p	tataaaagATGGCAaagaa	3	CUGCCAUG	m6b	Created	-0.145000	-0.288000	-2.100000
hsa-miR-4659b-5p	tataaaagATGGCAAagaa	3	UUGCCAUG	m7a	Created	-0.145000	-0.288000	-1.160000
hsa-miR-4776-3p	tataaaagATGGCAAagaa	3	CUUGCCAU	m7b	Created	-0.207000	-0.461000	-3.860000
hsa-miR-5590-5p	tataaaagATGGCAAagaa	3	UUGCCAUA	m7a	Created	-0.149000	-0.314000	-7.900000

Mutation			Mutation ID		Sample Name		Cancer Type
chr1:g.241801781G>A			COSN7988424		PCSI_0083_Pa_P_526		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-511	ataAAAGACAgcaaagaaa	0	GUGUCUUU	m7b	(m6b->m7b)	no TS	-0.115000	-0.160000
hsa-miR-626	ataaaAGACAGCaaagaaa	0	AGCUGUCU	m7b	Created	no TS	-0.430000	-0.870000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
241801780	rs191746925	C
			T	hsa-miR-4659a-5p hsa-miR-4659b-5p hsa-miR-4776-3p hsa-miR-5590-5p	1 1 1 1	aaaagATGGCAAa aaaagATGGCAAa aaaagATGGCAAA aaaagATGGCAAa	Created Created Created Created	N N N N	-0.143 -0.143 -0.254 -0.165

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