SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001017535
Gene Symbol: VDR
Description: Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor (VDR), transcript variant 1, mRNA.
Gene Location: chr12(-):48235319-48298814
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr12:g.47842120C>T COSN5796329 EOPC-010_tumor [prostate][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1253 accacCTTCTCagctctcc
 2
 AGAGAAGA m6b Created 0.029000 0.026000 -2.690000
hsa-miR-204-3p accaccTTCCCAGCtctcc
 2
 GCUGGGAA m8a Disrupted -0.307000 -0.288000 1.410000
hsa-miR-3160-3p accaccttcTCAGCTCTcc
 0 AGAGCUGA m8a (m7a->m8a) no TS -0.071000 -0.900000
hsa-miR-4251 accaccTTCTCAGctctcc
 4
 CCUGAGAA m7b Created 0.033000 0.048000 -0.030000
hsa-miR-4487 accaccttcCCAGCTCTcc
 6
 AGAGCUGG m8a (m8a->m7a) -0.130000 no TS 0.440000
hsa-miR-4646-5p accaccTTCCCAGctctcc
 2
 ACUGGGAA m7b Disrupted -0.306000 -0.278000 0.250000
hsa-miR-4747-5p accaCCTTCCCagctctcc
 1
 AGGGAAGG m7b Disrupted -0.378000 -0.164000 0.010000
hsa-miR-5196-5p accaCCTTCCCagctctcc
 1
 AGGGAAGG m7b Disrupted -0.397000 -0.183000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.47842714G>T COSN9562075 AOCS-155-3-5 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4714-3p gaggTAGGTTGatcacctg
 0 CCAACCUA m7b Created no TS 0.032000 -0.030000
hsa-miR-640 gaggtaggTGGATCAcctg
 1
 AUGAUCCA m7b Disrupted 0.093000 0.060000 0.110000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.47842735G>C ICGC_8616A8CA-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-106a-5p atcccaGCACTTTgggagg
 0 AAAAGUGC m7b Created no TS 0.096 -0.01
hsa-miR-106b-5p atcccaGCACTTTgggagg
 0 UAAAGUGC m7b Created no TS 0.115 No effect
hsa-miR-17-5p atcccaGCACTTTGggagg
 0 CAAAGUGC m8a Created no TS 0.096 -0.01
hsa-miR-186-3p atcccagcaCTTTGGGagg
 0 GCCCAAAG m7b (m6b->m7b) 0.081 0.043 -0.04
hsa-miR-20a-5p atcccaGCACTTTgggagg
 0 UAAAGUGC m7b Created no TS 0.106 No effect
hsa-miR-20b-5p atcccaGCACTTTGggagg
 0 CAAAGUGC m8a Created no TS 0.106 -0.01
hsa-miR-302a-3p atcccAGCACTTtgggagg
 0 UAAGUGCU m7b Created -0.384 -0.277 No effect
hsa-miR-302b-3p atcccAGCACTTtgggagg
 0 UAAGUGCU m7b Created -0.384 -0.277 No effect
hsa-miR-302c-3p atcccAGCACTTtgggagg
 0 UAAGUGCU m7b Created -0.384 -0.277 No effect
hsa-miR-302d-3p atcccAGCACTTtgggagg
 0 UAAGUGCU m7b Created -0.384 -0.277 No effect
hsa-miR-302e atcccAGCACTTtgggagg
 0 UAAGUGCU m7b Created -0.374 -0.258 No effect
hsa-miR-3692-5p atcCCAGCAGtttgggagg
 0 CCUGCUGG m7b (m7b->m6c) -0.022 no TS 0.11
hsa-miR-372 atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.395 -0.307 No effect
hsa-miR-373-3p atcccAGCACTTtgggagg
 0 GAAGUGCU m7b Created -0.374 -0.286 No effect
hsa-miR-512-3p atccCAGCACTTtgggagg
 0 AAGUGCUG m8a Created no TS 0.04 No effect
hsa-miR-519d atcccaGCACTTTGggagg
 0 CAAAGUGC m8a Created no TS 0.096 8.26
hsa-miR-520a-3p atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.374 -0.267 No effect
hsa-miR-520b atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.384 -0.296 No effect
hsa-miR-520c-3p atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.384 -0.296 No effect
hsa-miR-520d-3p atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.374 -0.267 No effect
hsa-miR-520e atcccAGCACTTTgggagg
 0 AAAGUGCU m8a Created -0.395 -0.288 No effect
hsa-miR-520g atcccagCACTTTGggagg
 0 ACAAAGUG m7b Created no TS 0.152 -0.03
hsa-miR-520h atcccagCACTTTGggagg
 0 ACAAAGUG m7b Created no TS 0.152 No effect
hsa-miR-526b-3p atcccaGCACTTTgggagg
 0 GAAAGUGC m7b Created no TS 0.096 No effect
hsa-miR-548av-3p atcccaGCAGTTTgggagg
 0 AAAACUGC m7b Disrupted 0.083 no TS No effect
hsa-miR-93-5p atcccaGCACTTTGggagg
 0 CAAAGUGC m8a Created no TS 0.106 -0.09

Mutation Mutation ID Sample Name Cancer Type
chr12:g.47843188T>G COSN9562076 AOCS-096-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4251 ccatgtcTCTCAGaattct
 4
 CCUGAGAA m6b Disrupted 0.033000 no TS 6.590000
hsa-miR-4329 ccatgtcTCTCAGaattct
 4
 CCUGAGAC m6b Disrupted 0.041000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.47843312A>G COSN5945151 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1260a gtcaGTGGGAacgtgactg
 4
 AUCCCACC m6b Disrupted -0.128000 -0.145000 No effect
hsa-miR-1260b gtcaGTGGGAacgtgactg
 4
 AUCCCACC m6b Disrupted -0.122000 -0.139000 0.010000
hsa-miR-188-3p gtcaGTGGGAacgtgactg
 4
 CUCCCACA m6b Disrupted -0.038000 -0.056000 2.550000
hsa-miR-3156-3p gtcAGTGGGAacgtgactg
 2
 CUCCCACU m7b (m7b->m6c) 0.002000 -0.008000 No effect
hsa-miR-4286 gtcAGTGGGGacgtgactg
 0 ACCCCACU m7b (m6c->m7b) -0.296000 -0.332000 -3.080000
hsa-miR-4301 gtcAGTGGGAacgtgactg
 0 UCCCACUA m7a (m7a->m6b) -0.130000 -0.096000 0.810000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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