| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_130839 |
|---|---|
| Gene Symbol: | UBE3A |
| Description: | Homo sapiens ubiquitin protein ligase E3A (UBE3A), transcript variant 2, mRNA. |
| Gene Location: | chr15(-):25582395-25684175 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr15:g.25337522C>A | COSN7039633 | 8034061 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-let-7a-2-3p |
gttaTGTACAataatgcta |
0 | CUGUACAG | m6b | Created | no TS | -0.098000 |
-0.020000 |
| hsa-let-7g-3p |
gttaTGTACAataatgcta |
0 | CUGUACAG | m6b | Created | no TS | -0.095000 |
-0.010000 |
| hsa-miR-1263 |
gttatGTACCATaatgcta |
0 | AUGGUACC | m7a | Disrupted | NA | NA |
5.470000 |
| hsa-miR-150-3p |
gttaTGTACCAtaatgcta |
10 |
CUGGUACA | m7b | Disrupted | -0.253000 | no TS | No effect |
| hsa-miR-493-5p |
gttATGTACAAtaatgcta |
19 |
UUGUACAU | m8a | Created | -0.119000 | -0.395000 |
-2.630000 |
| hsa-miR-5579-5p |
gttatGTACCATAatgcta |
10 |
UAUGGUAC | m8a | Disrupted | -0.411000 | no TS |
4.940000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr15:g.25337753T>A | COSN6268465 | RK308_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3074-3p |
acatTGATATatccttttg |
10 |
GAUAUCAG | m6b | Disrupted | -0.015000 | no TS |
9.610000 |
| hsa-miR-374a-3p |
acatTGATAAatccttttg |
0 | CUUAUCAG | m6b | Created | no TS | 0.000000 |
-0.010000 |
| hsa-miR-541-5p |
acattgataAATCCTTTtg |
11 |
AAAGGAUU | m8a | (m7a->m8a) | -0.213000 | -0.383000 | No effect |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr15:g.25338451C>A | COSN14985959 | SM-4AX85 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-129-5p |
acagcaCAAAAAattaaaa |
0 | CUUUUUGC | m6b | Created | -0.026000 | 0.054000 |
-2.530000 |
| hsa-miR-2113 |
acaGCACAAAaaattaaaa |
0 | AUUUGUGC | m7b | (m6c->m7b) | no TS | -0.211000 |
-0.130000 |
| hsa-miR-4775 |
acagcacaaAAAATTAAaa |
2 |
UUAAUUUU | m8a | (m7a->m8a) | 0.158000 | 0.147000 |
-2.840000 |
| hsa-miR-5010-3p |
acagCACAAAAaattaaaa |
0 | UUUUGUGU | m7a | Created | no TS | -0.014000 |
-4.480000 |
| hsa-miR-590-3p |
acagcacaaAAAATTAaaa |
0 | UAAUUUUA | m7a | (m6a->m7a) | no TS | 0.133000 |
-2.180000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr15:g.25338508G>T | COSN8171457 | PCSI_0305_Pa_P_526 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-3667-3p |
agatggaAGGAAGGgagaa |
0 | ACCUUCCU | m7b | Disrupted | -0.755000 | -0.509000 |
3.560000 |
| hsa-miR-3682-5p |
agatgGAAGTAagggagaa |
5 |
CUACUUCU | m6b | Created | -0.102000 | -0.137000 |
-2.360000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr15:g.25338688C>T | COSN15243785 | LP6007420-DNA_A01 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-302a-5p |
cgtaaccTTTAAGTatgtg |
0 | ACUUAAAC | m7a | Created | NA | NA |
-1.890000 |
| hsa-miR-4635 |
cgtaacCTTCAAGtatgtg |
15 |
UCUUGAAG | m7b | Disrupted | -0.091000 | no TS |
0.050000 |
| hsa-miR-493-3p |
cgtaACCTTCAagtatgtg |
15 |
UGAAGGUC | m7a | Disrupted | -0.260000 | -0.153000 |
0.020000 |
| hsa-miR-548m |
cgtaACCTTTaagtatgtg |
0 | CAAAGGUA | m6b | Created | no TS | -0.057000 |
-6.230000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr15:g.25339119T>C | ICGC_AD607A3C-2A78-11E2-8335-12FD496BB9B8 | CPCG_0102_Pr_P_P2 | ProstateCancer(OICR,CA) | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-19a-5p |
aaaacaaaaCAAAACaaaa |
0 | AGUUUUGC | m6b | Created | -0.06 | -0.1 |
-0.06 |
| hsa-miR-19b-1-5p |
aaaacaaaaCAAAACaaaa |
0 | AGUUUUGC | m6b | Created | -0.06 | -0.1 |
-0.68 |
| hsa-miR-19b-2-5p |
aaaacaaaaCAAAACaaaa |
0 | AGUUUUGC | m6b | Created | -0.06 | -0.1 |
-1.65 |
| hsa-miR-2052 |
aaaacaaaaCAAAACAaaa |
0 | UGUUUUGA | m7a | (m6a->m7a) | -0.528 | -0.88 |
-0.84 |