SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_052907 |
---|---|
Gene Symbol: | TMEM132B |
Description: | Homo sapiens transmembrane protein 132B (TMEM132B), mRNA. |
Gene Location: | chr12(+):125811161-126143589 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr12:g.125654889G>C | COSN14506609 | 8070208 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr12:g.125655227A>T | COSN9082444 | 8051728 | [pancreas][NS][carcinoid-endocrine_tumour][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-186-5p |
acctctggaATTCTTTttg |
6 |
CAAAGAAU | m7b | (m7b->m6c) | 0.009000 | no TS |
0.160000 |
|
hsa-miR-3180-5p |
accTCTGGAAttctttttg |
6 |
CUUCCAGA | m7b | (m7b->m6b) | -0.333000 | -0.256000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr12:g.125656488C>G | 0_395 | Lung cancer | |||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1208 |
gtttgggAACAGTGctgaa |
7 |
UCACUGUU | m7b | Disrupted | 0.196 | 0.094 |
0.24 |
|
hsa-miR-1236 |
gtttgGGAAGAGtgctgaa |
5 |
CCUCUUCC | m7b | Created | -0.066 | -0.013 | No effect | |
hsa-miR-642b-5p |
gtttGGGAACagtgctgaa |
1 |
GGUUCCCU | m6b | Disrupted | -0.043 | -0.042 |
0.03 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr12:g.125656721G>C | COSN1144192 | HX4T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3130-3p |
gagtttGGTGCAGaggtag |
0 | GCUGCACC | m7b | Disrupted | -0.077000 | 0.039000 |
8.100000 |
|
hsa-miR-3619-3p |
gagttTGGTCCagaggtag |
0 | GGGACCAU | m6b | Created | no TS | -0.033000 |
-0.160000 |
|
hsa-miR-378a-3p |
gagtttgGTCCAGaggtag |
2 |
ACUGGACU | m6b | Created | -0.024000 | -0.030000 | No effect | |
hsa-miR-378b |
gagtttgGTCCAGaggtag |
2 |
ACUGGACU | m6b | Created | -0.048000 | -0.051000 | No effect | |
hsa-miR-378c |
gagtttgGTCCAGaggtag |
2 |
ACUGGACU | m6b | Created | -0.024000 | -0.030000 |
-0.010000 |
|
hsa-miR-378d |
gagtttgGTCCAGaggtag |
2 |
ACUGGACU | m6b | Created | -0.024000 | -0.030000 | No effect | |
hsa-miR-378e |
gagtttgGTCCAGaggtag |
2 |
ACUGGACU | m6b | Created | -0.024000 | -0.030000 | No effect | |
hsa-miR-378f |
gagtttgGTCCAGaggtag |
2 |
ACUGGACU | m6b | Created | -0.024000 | -0.027000 | No effect | |
hsa-miR-378h |
gagtttgGTCCAGaggtag |
2 |
ACUGGACU | m6b | Created | -0.020000 | -0.026000 | No effect | |
hsa-miR-378i |
gagtttgGTCCAGaggtag |
2 |
ACUGGACU | m6b | Created | -0.020000 | -0.026000 | No effect | |
hsa-miR-422a |
gagtttgGTCCAGaggtag |
2 |
ACUGGACU | m6b | Created | -0.020000 | -0.026000 | No effect | |
hsa-miR-4638-3p |
gagtttgGTCCAGaggtag |
2 |
CCUGGACA | m6b | Created | -0.023000 | -0.028000 | No effect | |
hsa-miR-4776-5p |
gagttTGGTCCAgaggtag |
0 | GUGGACCA | m7b | Created | no TS | -0.050000 | No effect | |
hsa-miR-518c-5p |
gagtttggTCCAGAGgtag |
3 |
UCUCUGGA | m7b | Created | 0.103000 | 0.157000 | No effect | |
hsa-miR-3130-3p |
gagtttGGTGCAGaggtag |
0 | GCUGCACC | m7b | Disrupted | -0.077 | 0.039 |
8.1 |
|
hsa-miR-3619-3p |
gagttTGGTCCagaggtag |
0 | GGGACCAU | m6b | Created | no TS | -0.033 |
-0.16 |
|
hsa-miR-378a-3p |
gagtttgGTCCAGaggtag |
0 | ACUGGACU | m6b | Created | -0.024 | -0.03 | No effect | |
hsa-miR-378b |
gagtttgGTCCAGaggtag |
0 | ACUGGACU | m6b | Created | -0.048 | -0.051 | No effect | |
hsa-miR-378c |
gagtttgGTCCAGaggtag |
0 | ACUGGACU | m6b | Created | -0.024 | -0.03 |
-0.01 |
|
hsa-miR-378d |
gagtttgGTCCAGaggtag |
0 | ACUGGACU | m6b | Created | -0.024 | -0.03 | No effect | |
hsa-miR-378e |
gagtttgGTCCAGaggtag |
0 | ACUGGACU | m6b | Created | -0.024 | -0.03 | No effect | |
hsa-miR-378f |
gagtttgGTCCAGaggtag |
0 | ACUGGACU | m6b | Created | -0.024 | -0.027 | No effect | |
hsa-miR-378h |
gagtttgGTCCAGaggtag |
0 | ACUGGACU | m6b | Created | -0.02 | -0.026 | No effect | |
hsa-miR-378i |
gagtttgGTCCAGaggtag |
0 | ACUGGACU | m6b | Created | -0.02 | -0.026 | No effect | |
hsa-miR-422a |
gagtttgGTCCAGaggtag |
0 | ACUGGACU | m6b | Created | -0.02 | -0.026 | No effect | |
hsa-miR-4638-3p |
gagtttgGTCCAGaggtag |
0 | CCUGGACA | m6b | Created | -0.023 | -0.028 | No effect | |
hsa-miR-4776-5p |
gagttTGGTCCAgaggtag |
0 | GUGGACCA | m7b | Created | no TS | -0.05 | No effect | |
hsa-miR-518c-5p |
gagtttggTCCAGAGgtag |
0 | UCUCUGGA | m7b | Created | 0.103 | 0.157 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr12:g.125656892C>T | COSN4701173 | PD4107a | [breast][NS][carcinoma][ductal_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-658 |
gatgaaCCTCCGCtgaaac |
1 |
GGCGGAGG | m7b | Disrupted | -0.146000 | no TS |
0.350000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr12:g.125656954G>A | COSN7610432 | PCSI_0311_Pa_P_526 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-200c-5p |
tggtaaaGTAAGACGttgg |
12 |
CGUCUUAC | m8a | Created | -0.107000 | -0.123000 | No effect | |
hsa-miR-550a-3p |
tggtaaaGTAAGACgttgg |
12 |
UGUCUUAC | m7b | Created | -0.103000 | -0.091000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr12:g.125657118T>A | COSN7610433 | PCSI_0048_Pa_P_526 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4251 |
agtggtTTCTCAGcagggc |
3 |
CCUGAGAA | m7b | Disrupted | 0.179000 | 0.064000 |
0.140000 |
|
hsa-miR-4663 |
agtggtttCTCAGCagggc |
4 |
AGCUGAGC | m6b | Disrupted | -0.067000 | -0.098000 |
0.150000 |
|
hsa-miR-539-5p |
agtggTTTCTCagcagggc |
0 | GGAGAAAU | m6b | Disrupted | 0.260000 | 0.100000 |
2.150000 |
|
hsa-miR-93-3p |
agtggtttcTCAGCAGggc |
1 |
ACUGCUGA | m7b | (m7b->m6c) | -0.056000 | -0.111000 |
0.340000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr12:g.125657158C>T | COSN1561174 | RK001_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4422 |
aagATGCTTTTtgtgacaa |
0 | AAAAGCAU | m8a | Created | no TS | 0.119000 |
-0.160000 |
|
hsa-miR-513b |
aagatgcttCTTGTGAcaa |
2 |
UUCACAAG | m7b | (m7b->m6c) | 0.037000 | no TS |
0.400000 |
|
hsa-miR-4422 |
aagATGCTTTTtgtgacaa |
0 | AAAAGCAU | m8a | Created | no TS | 0.119 |
-0.16 |
|
hsa-miR-513b |
aagatgcttCTTGTGAcaa |
0 | UUCACAAG | m7b | (m7b->m6c) | 0.037 | no TS |
0.4 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr12:g.125657765T>A | COSN8699281 | AOCS-147-1-1 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3665 |
tgctcagaCACCTGCTgag |
6 |
AGCAGGUG | m8a | Created | -0.273000 | -0.317000 | No effect | |
hsa-miR-3934 |
tgctcagACACCTGctgag |
1 |
UCAGGUGU | m7b | Created | 0.053000 | 0.086000 | No effect | |
hsa-miR-4294 |
tgctcAGACTCCtgctgag |
1 |
GGGAGUCU | m7b | Disrupted | 0.004000 | 0.007000 |
1.480000 |
|
hsa-miR-4433-3p |
tgctcagACTCCTGctgag |
1 |
ACAGGAGU | m7b | Disrupted | -0.057000 | -0.120000 | No effect | |
hsa-miR-4722-5p |
tgctcagaCTCCTGCtgag |
0 | GGCAGGAG | m7b | Disrupted | -0.233000 | -0.205000 |
0.090000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr12:g.125658473T>A | COSN5933652 | RK128_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4636 |
gttttctaCACGAGTTacc |
0 | AACUCGUG | m8a | Created | no TS | -0.299000 |
-1.070000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr12:g.125658697C>T | 13_264 | SJRB004_D | Retinoblastoma | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4302 |
atgaaACACTGagtttttt |
0 | CCAGUGUG | m6b | Created | -0.033 | -0.15 |
-0.02 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
125654887 | rs184656890 | C | |||||||
C |
hsa-miR-3180-5p hsa-miR-499b-5p hsa-miR-520a-5p hsa-miR-525-5p |
0 |
ttaagTCTGGAAA ttAAGTCTGgaaa ttaagTCTGGAAa ttaagTCTGGAAa |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.251 -0.173 -0.129 -0.129 |
|||
125656082 | rs12308814 | C | C |
hsa-miR-1286 hsa-miR-4722-5p hsa-miR-491-3p |
5 2 8 |
cTCCTGCAtaatg CTCCTGCAtaatg ctccTGCATAAtg |
Disrupted Disrupted Disrupted |
N N N |
-0.081 -0.205 0.019 |
A |
hsa-miR-4433-3p hsa-miR-4459 hsa-miR-4768-3p hsa-miR-506-5p hsa-miR-892c-5p |
2 2 2 7 8 |
CTCCTGAataatg CTCCTGAataatg CTCCTGAataatg ctCCTGAATAatg ctcCTGAATAatg |
Created Created Created Created Created |
N N N N N |
-0.042 -0.019 -0.022 -0.105 0.036 |
|||
125656307 | rs183418941 | G | G |
hsa-miR-3977 |
2 |
ccTGAAGCAgtgc |
Disrupted |
N |
0.14 |
A |
hsa-miR-1208 hsa-miR-452-5p hsa-miR-4676-3p hsa-miR-892c-3p |
2 2 2 2 |
cctgaAACAGTGc cctgAAACAGTgc cctgAAACAGTgc cctgAAACAGTgc |
Created Created Created Created |
N N N N |
0.083 0.182 0.192 0.182 |
|||
125656721 | rs12823305 | G | G |
hsa-miR-3130-3p hsa-miR-4793-3p hsa-miR-767-5p |
2 2 2 |
tttGGTGCAGAgg tttgGTGCAGAgg ttTGGTGCAgagg |
Disrupted Disrupted Disrupted |
N N N |
-0.116 0.006 -0.014 |
125656722 | rs12824741 | C | C |
hsa-miR-3130-3p hsa-miR-4793-3p hsa-miR-767-5p |
2 2 2 |
ttGGTGCAGAggt ttgGTGCAGAggt tTGGTGCAgaggt |
Disrupted Disrupted Disrupted |
N N N |
-0.116 0.006 -0.014 |
G |
hsa-miR-6800-3p |
3 |
ttggtgGAGAGGT |
Created |
N |
-0.025 |
|||
125656894 | rs12823561 | G | G |
hsa-miR-658 hsa-miR-7846-3p |
1 1 |
aCCTCCGCtgaaa acCTCCGCTgaaa |
Disrupted Disrupted |
N N |
-0.146 -0.086 |
T |
hsa-miR-3942-3p hsa-miR-4257 hsa-miR-6847-5p |
1 1 1 |
acctccTCTGAAA acctCCTCTGAaa accTCCTCTGAaa |
Created Created Created |
N N N |
0.121 0.031 0.055 |
|||
125658390 | rs185041191 | G | G |
hsa-miR-584-3p hsa-miR-642a-5p hsa-miR-642b-5p |
2 2 2 |
gtgagGGAACTGt gtGAGGGAActgt gtgAGGGAACtgt |
Disrupted Disrupted Disrupted |
N N N |
-0.093 -0.074 -0.097 |
A |
hsa-miR-1238-3p hsa-miR-670-3p |
2 2 |
gtGAGGAAActgt gTGAGGAAActgt |
Created Created |
N N |
-0.034 -0.103 |
|||
125658551 | rs114658704 | A | G |
hsa-miR-1226-5p hsa-miR-3616-3p hsa-miR-4446-3p hsa-miR-4721 hsa-miR-6762-3p hsa-miR-6829-5p hsa-miR-93-3p |
1 1 1 1 1 1 1 |
tcagcaGCCCTCA tcagcaGCCCTCA tcagCAGCCCTca tcagcAGCCCTCA tcAGCAGCCctca tcaGCAGCCCtca TCAGCAGccctca |
Created Created Created Created Created Created Created |
N N N N N N N |
-0.232 -0.163 -0.194 -0.357 -0.179 -0.264 -0.111 |
A |
hsa-miR-296-3p hsa-miR-628-5p hsa-miR-6804-5p |
1 1 2 |
tcagCAACCCTca TCAGCAAccctca tcagcaACCCTCA |
Disrupted Disrupted Disrupted |
N N N |
-0.185 -0.103 -0.128 |