SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001080427 |
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Gene Symbol: | THSD7B |
Description: | Homo sapiens thrombospondin, type I, domain containing 7B (THSD7B), mRNA. |
Gene Location: | chr2(+):137748461-138435287 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr2:g.137676695C>A | COSN6191591 | RK308_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-376a-5p |
gagGAATCTAaagatgtga |
0 | GUAGAUUC | m7b | (m6b->m7b) | no TS | -0.268000 |
-0.310000 |
|
hsa-miR-4760-5p |
gaggAATCTAAAgatgtga |
10 |
UUUAGAUU | m8a | Created | -0.088000 | -0.226000 |
-0.020000 |
|
hsa-miR-5186 |
gaggAATCTCaagatgtga |
15 |
AGAGAUUG | m6b | Disrupted | -0.100000 | no TS |
-0.760000 |
|
hsa-miR-526b-5p |
gaggaatCTCAAGAtgtga |
14 |
CUCUUGAG | m7b | Disrupted | -0.356000 | -0.145000 |
0.070000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr2:g.137676722A>T | COSN8607544 | 3765_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-630 |
gcAGAATACTaatattgca |
12 |
AGUAUUCU | m8a | (m7a->m8a) | -0.263000 | -0.149000 |
1.160000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr2:g.137676795T>C | COSN5781967 | HCC93 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-548p |
gccaTTTTGCTttcaagtt |
0 | UAGCAAAA | m7b | Created | no TS | -0.125000 |
-0.050000 |
|
hsa-miR-570-3p |
gccatttTGTTTTCaagtt |
8 |
CGAAAACA | m7b | Disrupted | -0.196000 | no TS |
0.910000 |
|
hsa-miR-548p |
gccaTTTTGCTttcaagtt |
0 | UAGCAAAA | m7b | Created | no TS | -0.125000 |
-0.050000 |
|
hsa-miR-570-3p |
gccatttTGTTTTCaagtt |
8 |
CGAAAACA | m7b | Disrupted | -0.196000 | no TS |
0.910000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr2:g.137676993C>T | COSN6191592 | RK144_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-2115-3p |
cgagTCTGATactgcattg |
0 | CAUCAGAA | m6b | Created | no TS | -0.051000 |
-0.820000 |
hsa-miR-361-5p |
cgagTCTGATActgcattg |
0 | UUAUCAGA | m7b | Created | no TS | -0.071000 |
-5.170000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
137676718 | rs188725373 | A | A |
hsa-miR-3149 hsa-miR-4727-5p hsa-miR-4778-5p hsa-miR-5001-3p hsa-miR-630 hsa-miR-6738-3p |
10 17 14 17 12 17 |
ggcagaATACAAA GGCAGAAtacaaa ggCAGAATAcaaa GGCAGAAtacaaa ggcAGAATACAaa GGCAGAAtacaaa |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N |
-0.031 -0.224 -0.063 -0.207 -0.263 -0.246 |
G |
hsa-miR-3664-5p hsa-miR-4714-5p hsa-miR-514a-5p |
14 14 14 |
ggCAGAGTAcaaa ggCAGAGTAcaaa ggCAGAGTAcaaa |
Created Created Created |
N N N |
-0.132 -0.137 -0.133 |
|||
137677584 | rs147909697 | C | C |
hsa-miR-4760-5p hsa-miR-8061 |
10 10 |
taatATCTAAAac taatATCTAAAac |
Disrupted Disrupted |
N N |
-0.088 -0.078 |