SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_016569
Gene Symbol: TBX3
Description: Homo sapiens T-box 3 (TBX3), transcript variant 1, mRNA.
Gene Location: chr12(-):115108058-115121969
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr12:g.114670624G>C COSN1142680 HX17T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1915-5p aaaattgGGCAAGGagtgc
 0 ACCUUGCC m7b Created no TS -0.358000 -0.690000
hsa-miR-2355-5p aaaatTGGGGAaggagtgc
 2
 AUCCCCAG m6b Disrupted -0.128000 no TS 0.010000
hsa-miR-3667-3p aaaattggGGAAGGagtgc
 2
 ACCUUCCU m6b Disrupted -0.158000 -0.060000 0.450000
hsa-miR-502-5p aaaattggGCAAGGAgtgc
 0 AUCCUUGC m7b Created no TS -0.140000 -1.170000
hsa-miR-1915-5p aaaattgGGCAAGGagtgc
 0 ACCUUGCC m7b Created no TS -0.358 -0.69
hsa-miR-2355-5p aaaatTGGGGAaggagtgc
 0 AUCCCCAG m6b Disrupted -0.128 no TS 0.01
hsa-miR-3667-3p aaaattggGGAAGGagtgc
 0 ACCUUCCU m6b Disrupted -0.158 -0.06 0.45
hsa-miR-502-5p aaaattggGCAAGGAgtgc
 0 AUCCUUGC m7b Created no TS -0.14 -1.17

Mutation Mutation ID Sample Name Cancer Type
chr12:g.114671122G>T COSN5831363 SS6003311 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1226-5p caatcctttGCCCTCAaat
 2
 GUGAGGGC m7b (m7b->m6b) -0.367000 -0.119000 No effect
hsa-miR-3126-5p caatcctttTCCCTCAaat
 1
 UGAGGGAC m7a (m6a->m7a) -0.148000 -0.257000 No effect
hsa-miR-3616-3p caatccttTGCCCTCaaat
 2
 CGAGGGCA m7b Disrupted -0.323000 no TS No effect
hsa-miR-4419a caatcctttTCCCTCAaat
 1
 UGAGGGAG m7a (m6a->m7a) -0.512000 -0.603000 -0.030000
hsa-miR-4510 caatcctttTCCCTCAaat
 1
 UGAGGGAG m7a (m6a->m7a) -0.515000 -0.616000 -1.710000
hsa-miR-4668-5p caatccTTTTCCCTcaaat
 3
 AGGGAAAA m8a Created -0.206000 -0.218000 No effect
hsa-miR-4721 caatcctttGCCCTCAaat
 3
 UGAGGGCU m7a (m7a->m6a) -0.148000 no TS No effect
hsa-miR-4761-3p caatccttTGCCCTCaaat
 0 GAGGGCAU m7a Disrupted NA NA No effect
hsa-miR-5584-5p caatcctTTTCCCTcaaat
 0 CAGGGAAA m7b Created no TS -0.062000 No effect
hsa-miR-1226-5p caatcctttGCCCTCAaat
 2
 GUGAGGGC m7b (m7b->m6b) -0.367000 -0.119000 No effect
hsa-miR-3126-5p caatcctttTCCCTCAaat
 1
 UGAGGGAC m7a (m6a->m7a) -0.148000 -0.257000 No effect
hsa-miR-3616-3p caatccttTGCCCTCaaat
 2
 CGAGGGCA m7b Disrupted -0.323000 no TS No effect
hsa-miR-4419a caatcctttTCCCTCAaat
 1
 UGAGGGAG m7a (m6a->m7a) -0.512000 -0.603000 -0.030000
hsa-miR-4510 caatcctttTCCCTCAaat
 1
 UGAGGGAG m7a (m6a->m7a) -0.515000 -0.616000 -1.710000
hsa-miR-4668-5p caatccTTTTCCCTcaaat
 3
 AGGGAAAA m8a Created -0.206000 -0.218000 No effect
hsa-miR-4721 caatcctttGCCCTCAaat
 3
 UGAGGGCU m7a (m7a->m6a) -0.148000 no TS No effect
hsa-miR-4761-3p caatccttTGCCCTCaaat
 0 GAGGGCAU m7a Disrupted NA NA No effect
hsa-miR-5584-5p caatcctTTTCCCTcaaat
 0 CAGGGAAA m7b Created no TS -0.062000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.114671306T>C COSN5315890 RK307_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-185-3p ggagggaAGCCCCTaccat
 0 AGGGGCUG m7a Created -0.248000 -0.248000 -0.470000
hsa-miR-3199 ggagggaAGTCCCTaccat
 0 AGGGACUG m7a Disrupted NA NA 4.420000
hsa-miR-365a-5p ggagggAAGTCCCTaccat
 0 AGGGACUU m8a Disrupted -0.096000 no TS 4.110000
hsa-miR-365b-5p ggagggAAGTCCCTaccat
 0 AGGGACUU m8a Disrupted -0.096000 no TS 8.160000
hsa-miR-617 ggagGGAAGTCcctaccat
 0 AGACUUCC m7b Disrupted -0.090000 no TS 4.120000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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