SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_016524
Gene Symbol:	SYT17
Description:	Homo sapiens synaptotagmin XVII (SYT17), mRNA.
Gene Location:	chr16(+):19179637-19278554
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr16:g.19267176G>A			COSN7300342		8057559		[pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4658	tacACACTCACaacatgtc	0	GUGAGUGU	m8a	Created	no TS	-0.164000	-1.560000
hsa-miR-4737	tacacaCTCGCAacatgtc	0	AUGCGAGG	m6b	Disrupted	-0.229000	no TS	13.110000
hsa-miR-4758-5p	tacaCACTCACaacatgtc	0	GUGAGUGG	m7a	Created	NA	NA	-1.600000
hsa-miR-574-5p	taCACACTCAcaacatgtc	4	UGAGUGUG	m8a	(m7a->m8a)	-0.241000	-0.440000	-0.670000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
19267175	rs148182111	C	C	hsa-miR-4737 hsa-miR-574-5p	1 4	cacaCTCGCAAca CACACTCgcaaca	Disrupted Disrupted	N N	-0.229 -0.241
			T	hsa-miR-4684-3p hsa-miR-595 hsa-miR-6513-3p	1 4 1	cacacTTGCAACA CACACTTgcaaca cACACTTGcaaca	Created Created Created	N N N	-0.328 -0.225 -0.132

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