SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_005086
Gene Symbol: SSPN
Description: Homo sapiens sarcospan (Kras oncogene-associated gene) (SSPN), transcript variant 2, mRNA.
Gene Location: chr12(+):26348505-26387708
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr12:g.26231208A>G 9_95247 CRC-8-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3163 tatTTTTATAtttttatga
0 UAUAAAAU m7a (m7a->m6a) 0.665 0.635 0.01
hsa-miR-4803 tatttTTATGTTtttatga
4
UAACAUAA m7b Created no TS -0.166 -0.6

Mutation Mutation ID Sample Name Cancer Type
chr12:g.26231642G>T COSN14859945 LP2000108-DNA_A01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-151a-3p ttgcaaaAGTCTAGataac
0 CUAGACUG m7a Created NA NA No effect
hsa-miR-4305 ttgcaaaaGTCTAGataac
0 CCUAGACA m6b Created no TS -0.106000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.26232291G>C COSN7324737 8030032 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2276 cttgaCTTGCAGggtagtt
1
UCUGCAAG m7b Created -0.380000 -0.425000 -1.550000
hsa-miR-3691-3p cttGACTTGGagggtagtt
12
ACCAAGUC m7b (m7b->m6b) -0.093000 0.015000 0.050000
hsa-miR-5695 cttgaCTTGGAGggtagtt
3
ACUCCAAG m7b Disrupted -0.183000 -0.162000 0.050000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.26232507T>A COSN8707330 AOCS-143-1-0 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4275 gataaTAATTGagttcaat
9
CCAAUUAC m6b Disrupted 0.048000 -0.042000 No effect
hsa-miR-4680-5p gataataatAGAGTTCaat
2
AGAACUCU m7b (m6c->m7b) -0.018000 -0.103000 -0.080000
hsa-miR-4795-3p gatAATAATAgagttcaat
2
AUAUUAUU m7b (m6b->m7b) 0.138000 0.254000 No effect
hsa-miR-618 gataataaTAGAGTTcaat
0 AAACUCUA m7b Created no TS -0.022000 No effect
hsa-miR-944 gatAATAATTgagttcaat
8
AAAUUAUU m7b (m7b->m6b) 0.679000 0.524000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.26232527G>A COSN7324738 8016470 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4491 cgcctcTCCACATTgccta
0 AAUGUGGA m8a Created no TS 0.032000 -2.230000
hsa-miR-4657 cgcctcTCCACATTgccta
0 AAUGUGGA m8a Created no TS 0.032000 -0.880000
hsa-miR-658 cgcctCTCCGCattgccta
1
GGCGGAGG m6b Disrupted -0.082000 no TS 0.080000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.26233145A>C COSN8707331 AOCS-147-1-1 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-124-5p atagTGAACACtacaagtt
0 CGUGUUCA m7b Disrupted -0.093000 -0.066000 2.810000
hsa-miR-135b-3p atagtgaaCCCTACAagtt
0 AUGUAGGG m7b Created no TS -0.162000 -0.070000
hsa-miR-142-3p atagtgaACACTACAagtt
3
UGUAGUGU m8a Disrupted -0.109000 no TS 4.370000
hsa-miR-296-3p atagtgAACCCTacaagtt
0 GAGGGUUG m6b Created -0.028000 -0.050000 -0.900000
hsa-miR-4255 atagtGAACACTacaagtt
0 CAGUGUUC m7b Disrupted -0.215000 -0.172000 4.330000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.26233363C>T COSN1146557 HX13T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-147a atacacacaCACACACaca
0 GUGUGUGG m7a (m7a->m6b) 0.007000 0.007000 -0.600000
hsa-miR-223-5p atacacacATACACacaca
0 CGUGUAUU m6b Created 0.185000 0.213000 No effect
hsa-miR-297 atacacACATACAcacaca
0 AUGUAUGU m7b Created 0.029000 -0.001000 -0.810000
hsa-miR-567 atacacACATACacacaca
0 AGUAUGUU m6b Created 0.041000 0.077000 -0.240000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.26233415G>T COSN7324739 8062308 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-154-3p ctattGTATGATTaaatca
2
AAUCAUAC m8a Disrupted -0.059000 no TS 2.980000
hsa-miR-369-3p ctattGTATTATTaaatca
0 AAUAAUAC m8a Created no TS 0.011000 -2.320000
hsa-miR-374c-5p ctatTGTATTATtaaatca
0 AUAAUACA m8a Created no TS -0.014000 No effect
hsa-miR-4666a-3p ctATTGTATGattaaatca
1
CAUACAAU m8a (m8a->m7a) -0.069000 -0.097000 No effect
hsa-miR-485-3p ctatTGTATGAttaaatca
1
GUCAUACA m7b Disrupted -0.072000 no TS 0.120000
hsa-miR-487a ctattGTATGATTaaatca
2
AAUCAUAC m8a Disrupted -0.078000 no TS 2.710000
hsa-miR-539-3p ctatTGTATGATtaaatca
1
AUCAUACA m8a Disrupted -0.091000 no TS 0.090000
hsa-miR-5692b ctattgTATTATTaaatca
0 AAUAAUAU m7a Created NA NA 0.240000
hsa-miR-5692c ctattgTATTATTaaatca
0 AAUAAUAU m7a Created NA NA 0.650000
hsa-miR-655 ctatTGTATTATtaaatca
0 AUAAUACA m8a Created no TS -0.023000 -1.270000

Mutation Mutation ID Sample Name Cancer Type
chr12:g.26234072A>G COSN5939759 RK163_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-320a ggggtttcCAGCTTTacac
2
AAAAGCUG m7b Disrupted -0.027000 0.035000 No effect
hsa-miR-320b ggggtttcCAGCTTTacac
2
AAAAGCUG m7b Disrupted -0.031000 0.031000 No effect
hsa-miR-320c ggggtttcCAGCTTTacac
2
AAAAGCUG m7b Disrupted -0.027000 0.035000 No effect
hsa-miR-320d ggggtttcCAGCTTTacac
2
AAAAGCUG m7b Disrupted -0.027000 0.035000 No effect
hsa-miR-320e ggggtttCCAGCTTTacac
2
AAAGCUGG m8a Disrupted -0.151000 no TS No effect
hsa-miR-4429 ggggtttcCAGCTTTacac
2
AAAAGCUG m7b Disrupted -0.035000 0.027000 No effect
hsa-miR-875-3p ggggTTTCCAGctttacac
7
CCUGGAAA m7b Disrupted -0.002000 no TS No effect
hsa-miR-9-3p ggggtttccAGCTTTAcac
2
AUAAAGCU m7b (m7b->m6c) 0.037000 0.065000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.26234639T>C SSPN_E3_UTR_3 SJHYPO126_D Hypodiploid_ALL
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-21-3p cttTGGTGTTGtggattca
8
CAACACCA m8a Disrupted -0.223 -0.041 3.56
hsa-miR-3591-3p cttTGGTGTTgtggattca
8
AAACACCA m7b (m7b->m6b) -0.26 -0.041 3.48
hsa-miR-5003-5p ctttggTGTTGTGgattca
6
UCACAACA m7b Disrupted -0.199 -0.051 5.78
hsa-miR-5092 ctttggtgtCGTGGATTca
0 AAUCCACG m8a (m7b->m8a) no TS -0.246 No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.26234698T>C COSN1568486 RK020_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3668 attTCTACATgtttgaggt
3
AAUGUAGA m7b (m7b->m6b) -0.265000 -0.061000 1.600000
hsa-miR-3668 attTCTACATgtttgaggt
3
AAUGUAGA m7b (m7b->m6b) -0.265 -0.061 1.6

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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