SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001207018 |
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Gene Symbol: | SMTN |
Description: | Homo sapiens smoothelin (SMTN), transcript variant 4, mRNA. |
Gene Location: | chr22(+):31480981-31500610 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr22:g.31104348A>A | ICGC_45349 | TCGA-CF-A3MF-01A-12D-A21A-08 | BladderUrothelialCarcinoma(TCGA,US) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1306-5p |
tggtGGAGGTGGacgacat |
0 | CCACCUCC | m8a | Disrupted | -0.192 | no TS |
8.08 |
|
hsa-miR-5193 |
tggtgGAGGAGGAcgacat |
0 | UCCUCCUC | m8a | Created | no TS | -0.329 |
-10.8 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr22:g.31104444G>A | ICGC_1451298 | TCGA-A5-A0VP-01A-21D-A10B-09 | UterineCorpusEndometrioidCarcinoma(TCGA,US) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-143-5p |
acgaACTGCACCtgcgcgg |
0 | GGUGCAGU | m8a | Created | no TS | -0.112 |
-4.78 |
|
hsa-miR-3665 |
acgaactgCACCTGCgcgg |
0 | AGCAGGUG | m7b | Created | -0.151 | -0.29 |
-2.6 |
|
hsa-miR-764 |
acgaactGCACCTGCgcgg |
0 | GCAGGUGC | m8a | Created | no TS | -0.147 |
-3.9 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr22:g.31104457G>C | ICGC_1451299 | TCGA-B5-A11R-01A-11D-A122-09 | UterineCorpusEndometrioidCarcinoma(TCGA,US) | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4423-5p |
gcgcGGCAACaatgtctag |
0 | AGUUGCCU | m6b | Created | no TS | -0.111 |
0.14 |
hsa-miR-744-3p |
gcgcGGCAACAatgtctag |
0 | CUGUUGCC | m7b | Created | no TS | -0.23 |
-3.55 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
31104425 | rs115440473 | C | C |
hsa-miR-3665 hsa-miR-876-3p |
9 9 |
aacCACCTGCgac AACCACCtgcgac |
Disrupted Disrupted |
N N |
-0.151 -0.126 |
T |
hsa-miR-140-5p |
9 |
AACCACTtgcgac |
Created |
N |
-0.082 |
|||
31104429 | rs144949047 | G | |||||||
A |
hsa-miR-3665 hsa-miR-6511b-5p hsa-miR-657 hsa-miR-6811-5p |
8 13 8 13 |
ACCTGCAacgcca aCCTGCAAcgcca ACCTGCAacgcca aCCTGCAAcgcca |
Created Created Created Created |
N N N N |
-0.198 -0.106 -0.135 -0.116 |