SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_006444
Gene Symbol:	SMC2
Description:	Homo sapiens structural maintenance of chromosomes 2 (SMC2), transcript variant 1, mRNA.
Gene Location:	chr9(+):106856540-106903700
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr9:g.104141180T>C			COSN2303531		RK092_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-101-3p	ttgtatGTACTGTcatatt	0	UACAGUAC	m7b	Created	no TS	-0.212000	-0.230000
hsa-miR-4645-3p	ttgtatgTACTGTCatatt	5	AGACAGUA	m7b	Created	-0.224000	-0.549000	No effect
hsa-miR-101-3p	ttgtatGTACTGTcatatt	0	UACAGUAC	m7b	Created	no TS	-0.212	-0.23
hsa-miR-4645-3p	ttgtatgTACTGTCatatt	0	AGACAGUA	m7b	Created	-0.224	-0.549	No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
104139417	rs182138855	G	G	hsa-miR-802	7	tactgTGTTACTt	Disrupted	N	-0.164
			A	hsa-miR-101-3p hsa-miR-144-3p hsa-miR-374c-5p hsa-miR-655-3p	0	TACTGTAttactt TACTGTAttactt tacTGTATTActt tacTGTATTActt	Created Created Created Created	N N N N	-0.139 -0.125 -0.123 -0.141

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