SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
	Home	Search	Help	Download

Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_013272
Gene Symbol:	SLCO3A1
Description:	Homo sapiens solute carrier organic anion transporter family, member 3A1 (SLCO3A1), transcript variant 2, mRNA.
Gene Location:	chr15(+):92396937-92709137
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr15:g.92163311G>A			COSN8314126		TCGA-AN-A0AK-01		[breast][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3120-5p	agcCAGACAGGattcagaa	12	CCUGUCUG	m8a	Disrupted	-0.417000	-0.246000	1.140000
hsa-miR-3655	agccaGACAAGattcagaa	0	GCUUGUCG	m6b	Created	no TS	-0.120000	-2.170000
hsa-miR-4421	agccAGACAGGattcagaa	12	ACCUGUCU	m7b	Disrupted	-0.390000	-0.085000	-0.200000
hsa-miR-5699	agccAGACAGGAttcagaa	12	UCCUGUCU	m8a	Disrupted	-0.363000	-0.048000	1.620000

Mutation			Mutation ID		Sample Name		Cancer Type
chr15:g.92163375G>A			COSN1182059		HCC119T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-198	cgcggCTGGACCacagagt	0	GGUCCAGA	m7a	Created	NA	NA	-0.010000
hsa-miR-663b	cgcggctGGGCCACagagt	0	GGUGGCCC	m7b	Disrupted	-0.558000	-0.123000	10.500000
hsa-miR-198	cgcggCTGGACCacagagt	0	GGUCCAGA	m7a	Created	NA	NA	-0.01
hsa-miR-663b	cgcggctGGGCCACagagt	0	GGUGGCCC	m7b	Disrupted	-0.558	-0.123	10.5

Mutation			Mutation ID		Sample Name		Cancer Type
chr15:g.92163555T>A			COSN1182060		HX14T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-4775	taaaaAAAATTAAaaaaaa	0	UUAAUUUU	m8a	Disrupted	-0.052000	no TS	1.190000
hsa-miR-590-3p	taaaaAAAATTAaaaaaaa	0	UAAUUUUA	m7a	Disrupted	0.026000	-0.031000	0.740000
hsa-miR-4775	taaaaAAAATTAAaaaaaa	0	UUAAUUUU	m8a	Disrupted	-0.052	no TS	1.19
hsa-miR-590-3p	taaaaAAAATTAaaaaaaa	0	UAAUUUUA	m7a	Disrupted	0.026	-0.031	0.74

Mutation			Mutation ID		Sample Name		Cancer Type
chr15:g.92164814G>T			COSN8482158		AOCS-064-1-6		[ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3910	agcacactATGCCTTctac	0	AAAGGCAU	m7b	Created	no TS	0.041000	No effect
hsa-miR-4493	agcacactaGGCCTTCTac	2	AGAAGGCC	m8a	(m8a->m7b)	-0.101000	no TS	0.010000

Mutation			Mutation ID		Sample Name		Cancer Type
chr15:g.92164975G>A			COSN6413303		HX30T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-551b-5p	ggttgaTTGATTTgctttt	0	GAAAUCAA	m7b	Created	no TS	0.061000	-0.710000

Mutation			Mutation ID		Sample Name		Cancer Type
chr15:g.92165717A>G			COSN1689057		RK091_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change

No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
92163555	rs201988923	T	T	hsa-miR-4775 hsa-miR-590-3p	0	aaAAAATTAAaaa aaAAAATTAaaaa	Disrupted Disrupted	N N	-0.052 0.057
92163555	rs71770667	-	TT	hsa-miR-4775 hsa-miR-590-3p	0	aaaAAAATTAAaaaa aaaAAAATTAaaaaa	Unknown Unknown	N N	-0.052 0.057
			-
92163555	rs72182901	-	T	hsa-miR-4775 hsa-miR-590-3p	0	aaAAAATTAAaaa aaAAAATTAaaaa	Unknown Unknown	N N	-0.052 0.057
			-
92163556	rs77430410	A	T	hsa-miR-4775 hsa-miR-590-3p	0	aAAAATTAAaaaa aAAAATTAaaaaa	Created Created	N N	-0.052 0.057
92163557	rs34029747	-	A	hsa-miR-4775 hsa-miR-590-3p	0	AAAATTAAaaaaa AAAATTAaaaaaa	Unknown Unknown	N N	-0.004 -0.002
			-
92164975	rs199764055	G	G	hsa-miR-6715a-3p	7	tgatTGGTTTGct	Disrupted	N	-0.087
			A	hsa-miR-4705 hsa-miR-551b-5p	2 6	TGATTGAtttgct tgaTTGATTTgct	Created Created	N N	0.007 0.061

Genome Browser