SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_003615 |
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Gene Symbol: | SLC4A7 |
Description: | Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 7 (SLC4A7), mRNA. |
Gene Location: | chr3(-):27414213-27498245 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.27373016A>T | COSN14909020 | LP6005409-DNA_F02 | [oesophagus][NS][carcinoma][adenocarcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-16-2-3p |
ataaataAATATTGaattt |
0 | CCAAUAUU | m7b | Created | 0.006000 | -0.190000 | No effect | |
hsa-miR-195-3p |
ataaataAATATTGaattt |
0 | CCAAUAUU | m7b | Created | 0.009000 | -0.166000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.27373270A>G | ICGC_531839 | TCGA-A6-2672-01A-01W-0833-10 | ColonAdenocarcinoma(TCGA,US) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4659a-5p |
cattaaATGGCAattatag |
0 | CUGCCAUG | m6b | Created | no TS | -0.143 |
-3.38 |
|
hsa-miR-4776-3p |
cattaaATGGCAAttatag |
0 | CUUGCCAU | m7b | Created | no TS | -0.221 |
-0.05 |
|
hsa-miR-489 |
cattaaATGTCAattatag |
0 | GUGACAUC | m6b | Disrupted | -0.099 | no TS |
0.11 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.27373326G>T | ICGC_434377 | TCGA-AZ-6600-01A-11D-1771-10 | ColonAdenocarcinoma(TCGA,US) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-192-3p |
caaaatTTGGCAatcttca |
0 | CUGCCAAU | m6b | Disrupted | -0.148 | -0.024 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.27373327G>A | ICGC_406828 | TCGA-AA-3697-01A-01D-1719-10 | ColonAdenocarcinoma(TCGA,US) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-192-3p |
gcaaaatTTGGCAatcttc |
0 | CUGCCAAU | m6b | Disrupted | -0.148 | -0.024 |
0.01 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.27374015T>C | COSN6573947 | ICGC_MB82 | [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-889 |
ttaatGATATTAAatatgc |
2 |
UUAAUAUC | m8a | Disrupted | 0.068000 | no TS |
0.950000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.27374120A>T | COSN6764222 | RK216_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3133 |
ctgaaatGTTCTTTttttc |
4 |
UAAAGAAC | m7b | Created | 0.435000 | 0.484000 |
-0.120000 |
|
hsa-miR-548av-5p |
ctgaaatGTACTTTTtttc |
2 |
AAAAGUAC | m8a | Disrupted | 0.149000 | 0.167000 |
1.470000 |
|
hsa-miR-548k |
ctgaaatGTACTTTTtttc |
2 |
AAAAGUAC | m8a | Disrupted | 0.149000 | 0.167000 |
4.020000 |
|
hsa-miR-548n |
ctgaaatgTACTTTTtttc |
5 |
CAAAAGUA | m7b | Disrupted | 0.242000 | 0.130000 |
2.970000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.27375847C>A | ICGC_398619 | TCGA-AA-3492-01A-01D-1408-10 | ColonAdenocarcinoma(TCGA,US) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-4764-3p |
tcaGGAGTTAgaattctct |
0 | UUAACUCC | m7b | (m7b->m6c) | -0.107 | -0.107 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr3:g.27376240G>A | COSN6764223 | RK308_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr3:g.27376615C>G | COSN1275459 | HCC115T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1250 |
aatgAGCACCGTggagact |
4 |
ACGGUGCU | m8a | Disrupted | -0.298000 | no TS |
0.470000 |
hsa-miR-3907 |
aatGAGCACCgtggagact |
11 |
AGGUGCUC | m7b | (m7b->m6c) | -0.289000 | no TS |
6.710000 |
hsa-miR-1250 |
aatgAGCACCGTggagact |
4 |
ACGGUGCU | m8a | Disrupted | -0.298000 | no TS |
0.470000 |
hsa-miR-3907 |
aatGAGCACCgtggagact |
11 |
AGGUGCUC | m7b | (m7b->m6c) | -0.289000 | no TS |
6.710000 |
hsa-miR-1250 |
aatgAGCACCGTggagact |
0 | ACGGUGCU | m8a | Disrupted | -0.298 | no TS |
0.47 |
hsa-miR-3907 |
aatGAGCACCgtggagact |
0 | AGGUGCUC | m7b | (m7b->m6c) | -0.289 | no TS |
6.71 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
27375688 | rs41295960 | A | A |
hsa-miR-190a-3p hsa-miR-369-3p hsa-miR-374a-5p hsa-miR-374b-5p hsa-miR-410-3p hsa-miR-5692b hsa-miR-5692c hsa-miR-6083 |
7 4 4 4 6 4 4 6 |
aatatTATATAAa aaTATTATAtaaa aaTATTATAtaaa aaTATTATAtaaa aataTTATATAaa aATATTATAtaaa aATATTATAtaaa aatattATATAAA |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N |
0.102 0.072 0.01 0.001 0.083 0.073 0.073 0.1 |
G |
hsa-let-7a-3p hsa-let-7b-3p hsa-let-7f-1-3p hsa-let-7f-2-3p hsa-miR-1185-1-3p hsa-miR-1185-2-3p hsa-miR-16-2-3p hsa-miR-195-3p hsa-miR-300 hsa-miR-338-5p hsa-miR-381-3p hsa-miR-4666a-3p hsa-miR-4789-5p hsa-miR-98-3p |
6 6 6 7 7 7 4 4 6 4 6 4 7 6 |
aataTTGTATAAa aataTTGTATAAa aataTTGTATAAa aatatTGTATAAa aatatTGTATAAa aatatTGTATAAa AATATTGtataaa AATATTGtataaa aataTTGTATAaa aATATTGTAtaaa aataTTGTATAaa aatATTGTATAaa aatatTGTATAAa aataTTGTATAAa |
Created Created Created Created Created Created Created Created Created Created Created Created Created Created |
N N N N N N N N N N N N N N |
0.013 -0.008 -0.029 0.03 0.023 0.023 -0.025 -0.016 0.036 -0.015 0.023 -0.012 0.021 -0.008 |