SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_000112
Gene Symbol: SLC26A2
Description: Homo sapiens solute carrier family 26 (sulfate transporter), member 2 (SLC26A2), mRNA.
Gene Location: chr5(+):149340299-149366963

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr5:g.149982860T>C COSN9928589 C0096T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-433 tatTCATGATagctggccc
 3
 AUCAUGAU m7a (m7a->m6a) 0.034000 0.036000 0.760000
hsa-miR-96-3p tattCATGATagctggccc
 2
 AAUCAUGU m6b Disrupted 0.027000 no TS No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149983438G>A COSN9411280 AOCS-150-3-1 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4282 ctgAATTTTAacatccttt
 11
 UAAAAUUU m7a (m6a->m7a) 0.919000 1.152000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149983535C>G COSN9411281 AOCS-104-1-6 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1287 cctttctATCCAGCcttat
 3
 UGCUGGAU m7b Disrupted -0.063000 no TS 0.890000
hsa-miR-153 cctttCTATGCAgccttat
 0 UUGCAUAG m7b Created no TS -0.012000 -0.030000
hsa-miR-3652 cctttctaTCCAGCCttat
 2
 CGGCUGGA m7b Disrupted -0.186000 -0.064000 0.050000
hsa-miR-4430 cctttctaTCCAGCCTtat
 2
 AGGCUGGA m8a Disrupted -0.166000 -0.054000 0.560000
hsa-miR-5191 cctttCTATCCagccttat
 5
 AGGAUAGG m6b Disrupted 0.007000 no TS 2.390000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149983838G>A ICGC_79719A30-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-204-3p agccTCCCAGagtgttggg
 3
 GCUGGGAA m6b Disrupted -0.24 -0.28 No effect
hsa-miR-30b-3p agCCTCCCAGagtgttggg
 0 CUGGGAGG m8a (m8a->m7a) 0.061 0.023 -0.04
hsa-miR-30c-1-3p agcCTCCCAGagtgttggg
 0 CUGGGAGA m7a (m7a->m6a) 0.12 0.159 0.01
hsa-miR-30c-2-3p agcCTCCCAGagtgttggg
 0 CUGGGAGA m7a (m7a->m6a) 0.121 0.147 0.02
hsa-miR-3122 agccTCCCAAagtgttggg
 0 GUUGGGAC m6b Created no TS 0.066 No effect
hsa-miR-3192 agcCTCCCAGAgtgttggg
 3
 UCUGGGAG m8a Disrupted 0.065 0.011 0.77
hsa-miR-326 agcctCCCAGAGtgttggg
 3
 CCUCUGGG m7b Disrupted -0.016 -0.04 0.08
hsa-miR-330-5p agcctCCCAGAGtgttggg
 3
 UCUCUGGG m7b Disrupted -0.006 -0.021 0.41
hsa-miR-3689a-3p agCCTCCCAGagtgttggg
 0 CUGGGAGG m8a (m8a->m7a) 0.074 0.035 No effect
hsa-miR-3689b-3p agCCTCCCAGagtgttggg
 0 CUGGGAGG m8a (m8a->m7a) 0.074 0.035 No effect
hsa-miR-3689c agCCTCCCAGagtgttggg
 0 CUGGGAGG m8a (m8a->m7a) 0.074 0.035 No effect
hsa-miR-4314 agccTCCCAGAGtgttggg
 3
 CUCUGGGA m8a Disrupted 0.121 0.039 No effect
hsa-miR-4646-5p agccTCCCAGagtgttggg
 3
 ACUGGGAA m6b Disrupted -0.244 -0.277 1.55
hsa-miR-514a-5p agcctcCCAGAGTgttggg
 3
 UACUCUGG m7b Disrupted 0.077 0.034 0.03

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149984415G>T ICGC_79719EFE-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-106a-5p tcccaGCACTTTgggaggc
 0 AAAAGUGC m7b Created no TS 0.143 -0.49
hsa-miR-106b-5p tcccaGCACTTTgggaggc
 0 UAAAGUGC m7b Created no TS 0.162 -0.05
hsa-miR-17-5p tcccaGCACTTTGggaggc
 0 CAAAGUGC m8a Created no TS 0.143 -0.49
hsa-miR-186-3p tcccagcaCTTTGGGaggc
 0 GCCCAAAG m7b Created no TS 0.135 No effect
hsa-miR-20a-5p tcccaGCACTTTgggaggc
 0 UAAAGUGC m7b Created no TS 0.153 -1.42
hsa-miR-20b-5p tcccaGCACTTTGggaggc
 0 CAAAGUGC m8a Created no TS 0.153 -1.5
hsa-miR-302a-3p tcccAGCACTTtgggaggc
 0 UAAGUGCU m7b Created no TS 0.152 -0.02
hsa-miR-302b-3p tcccAGCACTTtgggaggc
 0 UAAGUGCU m7b Created no TS 0.152 No effect
hsa-miR-302c-3p tcccAGCACTTtgggaggc
 0 UAAGUGCU m7b Created no TS 0.152 No effect
hsa-miR-302d-3p tcccAGCACTTtgggaggc
 0 UAAGUGCU m7b Created no TS 0.152 -0.01
hsa-miR-302e tcccAGCACTTtgggaggc
 0 UAAGUGCU m7b Created no TS 0.161 -0.02
hsa-miR-372 tcccAGCACTTTgggaggc
 0 AAAGUGCU m8a Created no TS 0.133 -0.19
hsa-miR-373-3p tcccAGCACTTtgggaggc
 0 GAAGUGCU m7b Created no TS 0.133 -0.09
hsa-miR-512-3p tccCAGCACTTtgggaggc
 0 AAGUGCUG m8a Created no TS 0.085 No effect
hsa-miR-519d tcccaGCACTTTGggaggc
 0 CAAAGUGC m8a Created no TS 0.143 No effect
hsa-miR-520a-3p tcccAGCACTTTgggaggc
 0 AAAGUGCU m8a Created no TS 0.152 No effect
hsa-miR-520b tcccAGCACTTTgggaggc
 0 AAAGUGCU m8a Created no TS 0.133 -0.03
hsa-miR-520c-3p tcccAGCACTTTgggaggc
 0 AAAGUGCU m8a Created no TS 0.133 -0.01
hsa-miR-520d-3p tcccAGCACTTTgggaggc
 0 AAAGUGCU m8a Created no TS 0.152 No effect
hsa-miR-520e tcccAGCACTTTgggaggc
 0 AAAGUGCU m8a Created no TS 0.152 No effect
hsa-miR-520g tcccagCACTTTGggaggc
 0 ACAAAGUG m7b Created no TS 0.202 -0.06
hsa-miR-520h tcccagCACTTTGggaggc
 0 ACAAAGUG m7b Created no TS 0.202 -0.05
hsa-miR-526b-3p tcccaGCACTTTgggaggc
 0 GAAAGUGC m7b Created no TS 0.143 -0.05
hsa-miR-93-5p tcccaGCACTTTGggaggc
 0 CAAAGUGC m8a Created no TS 0.153 -1.88

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149984478T>G ICGC_7971A426-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-128 ggctaaCACTGTGAaaccc
 1
 UCACAGUG m8a Disrupted 0.032 0.011 No effect
hsa-miR-27a-3p ggctaacACTGTGAAaccc
 1
 UUCACAGU m8a Disrupted 0.095 no TS 0.1
hsa-miR-27b-3p ggctaacACTGTGAAaccc
 1
 UUCACAGU m8a Disrupted 0.095 no TS 0.17
hsa-miR-3681-3p ggctaaCACTGTGaaaccc
 1
 ACACAGUG m7b Disrupted 0.039 0.039 0.01
hsa-miR-5096 ggctaacacGGTGAAACcc
 0 GUUUCACC m8a (m7b->m8a) no TS 0.125 0.22
hsa-miR-513a-5p ggctaacaCTGTGAAaccc
 0 UUCACAGG m7a Disrupted 0.033 -0.04 No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149984625G>C ICGC_7971A908-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1289 gtgccactGGACTCCAgcc
 0 UGGAGUCC m8a Disrupted -0.073 no TS No effect
hsa-miR-143-5p gtgccACTGCACtccagcc
 0 GGUGCAGU m7b Created 0.055 0.097 -1.61
hsa-miR-194-3p gtgCCACTGGactccagcc
 0 CCAGUGGG m7a (m7a->m6a) NA NA 0.2
hsa-miR-199a-5p gtgcCACTGGactccagcc
 1
 CCCAGUGU m6b Disrupted 0.043 no TS 0.01
hsa-miR-199b-5p gtgcCACTGGactccagcc
 1
 CCCAGUGU m6b Disrupted 0.043 no TS No effect
hsa-miR-3198 gtgccactgGACTCCAgcc
 0 GUGGAGUC m7b (m7b->m6c) 0.079 no TS No effect
hsa-miR-4294 gtgccactgGACTCCagcc
 0 GGGAGUCU m6b Disrupted 0.077 0.056 No effect
hsa-miR-4309 gtgccactgGACTCCAGcc
 0 CUGGAGUC m8a (m8a->m7b) 0.097 no TS 0.01
hsa-miR-5693 gtGCCACTGCactccagcc
 0 GCAGUGGC m8a (m7a->m8a) -0.011 -0.011 0.7

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149984782->CCC 4_3541 myeloid Acute
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4509 ctctaaaCTTTAGagtctaaatg
 5
 ACUAAAGG m6b Disrupted 0.064000 no TS -0.880000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149984873T>C COSN5591998 RK279_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-181c-3p tcttGATGGTTagaactct
 0 AACCAUCG m7a Disrupted -0.029000 -0.029000 1.250000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149985935G>A COSN9411282 AOCS-001-1-7 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-323a-3p ggaggcaGTAATGTccctg
 1
 CACAUUAC m7b Created -0.030000 0.114000 No effect
hsa-miR-3913-3p ggaggcagTGATGTCcctg
 1
 AGACAUCA m7b Disrupted 0.043000 -0.051000 No effect
hsa-miR-499a-3p ggaggcaGTGATGTccctg
 2
 AACAUCAC m7b Disrupted -0.001000 -0.090000 No effect
hsa-miR-499b-3p ggaggcaGTGATGTccctg
 2
 AACAUCAC m7b Disrupted -0.011000 -0.100000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149985959A>C COSN6584119 ICGC_MB125 [central_nervous_system][brain][primitive_neuroectodermal_tumour-medulloblastoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3124-3p ttcagGGAAAGatttcagt
 6
 ACUUUCCU m6b Disrupted -0.054000 -0.111000 No effect
hsa-miR-4446-5p ttcAGGGAAAgatttcagt
 3
 AUUUCCCU m7b (m7b->m6b) -0.020000 -0.077000 0.010000
hsa-miR-642b-5p ttcAGGGAACgatttcagt
 1
 GGUUCCCU m7b (m6b->m7b) -0.096000 -0.113000 No effect

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149986362G>T COSN2076465 RK066_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-2355-3p atggaaaAGGACAAaataa
 0 AUUGUCCU m7b Disrupted -0.208000 no TS No effect
hsa-miR-4646-3p atggaaaaGGACAAaataa
 0 AUUGUCCC m6b Disrupted -0.084000 no TS No effect
hsa-miR-5003-3p atgGAAAAGTAcaaaataa
 5
 UACUUUUC m8a Created 0.235000 0.253000 -0.060000
hsa-miR-676-3p atggaaaAGGACAaaataa
 0 CUGUCCUA m6b Disrupted -0.096000 no TS 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149987151T>C COSN14747397 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-144-3p gttttATACTGTAtttttt
 0 UACAGUAU m8a Disrupted -0.431000 -0.088000 0.670000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.149987366G>A COSN14774786 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-7-1-3p gtttcATTTGTTttgtctg
 0 CAACAAAU m7b Disrupted 0.333000 0.408000 0.090000
hsa-miR-7-2-3p gtttcATTTGTTttgtctg
 0 CAACAAAU m7b Disrupted 0.321000 0.405000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
149981896 rs143847430 T T hsa-miR-1468-3p
hsa-miR-19a-3p
hsa-miR-19b-3p
hsa-miR-3606-3p
hsa-miR-4282
hsa-miR-513a-3p
hsa-miR-513c-3p
hsa-miR-548aj-5p
hsa-miR-548aw
hsa-miR-548f-5p
hsa-miR-548g-5p
hsa-miR-548x-5p
2
2
2
1
2
1
1
2
2
2
2
2
 ggaaATTTTGCAc
ggaaatTTTGCAC
ggaaatTTTGCAC
gGAAATTTtgcac
ggAAATTTTgcac
gGAAATTTtgcac
gGAAATTTtgcac
ggaaaTTTTGCAc
ggaaaTTTTGCAc
ggaaaTTTTGCAc
ggaaaTTTTGCAc
ggaaaTTTTGCAc
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
N
N
N
N
N
 -0.203
-0.205
-0.205
0.023
0.108
0.033
0.033
-0.037
-0.137
-0.044
-0.037
-0.037
149982083 rs146843578 T T hsa-miR-101-3p
hsa-miR-144-3p
hsa-miR-582-5p
1
1
7
 ctGTACTGTAaag
ctgTACTGTAaag
ctgtACTGTAAag
 Disrupted
Disrupted
Disrupted
N
N
N
 -0.341
-0.088
-0.085
A hsa-let-7a-2-3p
hsa-let-7g-3p
hsa-miR-1183
hsa-miR-4693-5p
1
1
1
7
 CTGTACAgtaaag
CTGTACAgtaaag
ctgTACAGTAaag
ctgtACAGTAAag
 Created
Created
Created
Created
N
N
N
N
 -0.199
-0.181
-0.097
-0.094
149982359 rs183837786 G G hsa-miR-155-3p
hsa-miR-3124-3p
hsa-miR-3685
hsa-miR-384
4
6
4
5
 ttaGTAGGAAagt
ttagtAGGAAAGt
ttaGTAGGAAAgt
ttagTAGGAAAgt
 Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
 -0.098
-0.062
-0.208
-0.027
149983631 rs186726602 G G hsa-miR-4793-3p
hsa-miR-514a-5p
hsa-miR-7703
2
2
2
 gccagAGTGCAGt
gCCAGAGTgcagt
gccaGAGTGCAgt
 Disrupted
Disrupted
Disrupted
N
N
N
 0.009
0.012
-0.045
A hsa-miR-20a-3p
hsa-miR-217
hsa-miR-6807-3p
2
2
2
 gccagAATGCAGt
gccagaATGCAGT
gccagaATGCAGT
 Created
Created
Created
N
N
N
 0.068
0.001
0.011
149983783 rs147208348 G G hsa-miR-1285-3p
hsa-miR-196a-3p
hsa-miR-3187-5p
hsa-miR-5189-5p
hsa-miR-612
hsa-miR-6860
hsa-miR-939-3p
1
1
1
1
1
1
1
 tgtgtTGCCCAGg
tgTGTTGCCcagg
tgtgtTGCCCAGg
tgtgtTGCCCAGg
tgtgtTGCCCAGg
tgtgtTGCCCAGg
tgtgttGCCCAGG
 Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
Disrupted
N
N
N
N
N
N
N
 -0.076
0.068
-0.011
0.008
-0.002
-0.011
-0.026
T hsa-miR-204-3p
hsa-miR-3153
hsa-miR-4261
hsa-miR-4646-5p
hsa-miR-4668-5p
hsa-miR-6733-5p
hsa-miR-6739-5p
1
1
1
1
1
1
1
 tgtgtTTCCCAGg
tgtgTTTCCCAgg
tgTGTTTCCcagg
tgtgtTTCCCAGg
tgtgTTTCCCAgg
tgtgTTTCCCAgg
tgtgTTTCCCAgg
 Created
Created
Created
Created
Created
Created
Created
N
N
N
N
N
N
N
 0.053
0.091
0.104
0.043
0.096
0.094
0.084
149985312 rs76297937 T
A hsa-miR-32-3p
hsa-miR-4282
hsa-miR-7702
0 gtCTAAATTtttt
gtctAAATTTTtt
GTCTAAAtttttt
 Created
Created
Created
N
N
N
 0.076
0.169
0.019
149987151 rs17711997 T T hsa-miR-101-3p
hsa-miR-144-3p
1
1
 ttaTACTGTAttt
ttATACTGTAttt
 Disrupted
Disrupted
N
N
 -0.123
-0.343
149987366 rs10476926 A G hsa-miR-7-1-3p
hsa-miR-7-2-3p
0 tcATTTGTTttgt
tcATTTGTTttgt
 Created
Created
N
N
 -0.075
-0.084
A hsa-miR-1252-3p
hsa-miR-3646
0 TCATTTAttttgt
TCATTTAttttgt
 Disrupted
Disrupted
N
N
 -0.032
-0.083

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