SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_020689
Gene Symbol: SLC24A3
Description: Homo sapiens solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 (SLC24A3), mRNA.
Gene Location: chr20(+):19193289-19703541
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr20:g.19721877C>T COSN1246172 HX4T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4432 cgctaaAGTCTTatgggcg
 3
 AAAGACUC m6b Disrupted 0.015000 no TS 3.210000
hsa-miR-499a-5p cgctaaAGTCTTAtgggcg
 3
 UUAAGACU m7b Disrupted -0.005000 no TS 3.270000
hsa-miR-548a-3p cgctaaAGTTTTatgggcg
 0 CAAAACUG m6b Created no TS 0.120000 -0.040000
hsa-miR-548e cgctaaAGTTTTatgggcg
 0 AAAAACUG m6b Created no TS 0.124000 -0.360000
hsa-miR-548f cgctaaAGTTTTatgggcg
 0 AAAAACUG m6b Created no TS 0.120000 -0.020000
hsa-miR-5582-3p cgctaAAGTTTTAtgggcg
 0 UAAAACUU m8a Created no TS 0.130000 -0.360000
hsa-miR-4432 cgctaaAGTCTTatgggcg
 3
 AAAGACUC m6b Disrupted 0.015 no TS 3.21
hsa-miR-499a-5p cgctaaAGTCTTAtgggcg
 3
 UUAAGACU m7b Disrupted -0.005 no TS 3.27
hsa-miR-548a-3p cgctaaAGTTTTatgggcg
 0 CAAAACUG m6b Created no TS 0.12 -0.04
hsa-miR-548e cgctaaAGTTTTatgggcg
 0 AAAAACUG m6b Created no TS 0.124 -0.36
hsa-miR-548f cgctaaAGTTTTatgggcg
 0 AAAAACUG m6b Created no TS 0.12 -0.02
hsa-miR-5582-3p cgctaAAGTTTTAtgggcg
 0 UAAAACUU m8a Created no TS 0.13 -0.36


Mutation Mutation ID Sample Name Cancer Type
chr20:g.19722125G>T COSN5966619 RK200_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr20:g.19722350C>T 10_17797 6408 Breast cancer
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3154 cctCCCTTCTtggagggat
 9
 CAGAAGGG m7b (m6b->m7b) no TS -0.059 0.67
hsa-miR-3202 cctCCCTTCCtggagggat
 9
 UGGAAGGG m7b (m7b->m6b) -0.086 no TS 0.12
hsa-miR-4476 cctcCCTTCCTGgagggat
 7
 CAGGAAGG m8a Disrupted -0.03 -0.015 No effect
hsa-miR-5695 cctcccttCTTGGAGggat
 18
 ACUCCAAG m7b Created -0.057 -0.1 No effect
hsa-miR-665 cctccctTCCTGGagggat
 17
 ACCAGGAG m6b Disrupted -0.028 no TS 0.08

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
19722286 rs143524610 T T hsa-miR-335-5p
15
 tgGCTCTTGggca
 Disrupted
N
 -0.001
C hsa-miR-505-5p
hsa-miR-665
hsa-miR-6840-3p
15
15
21
 TGGCTCCtgggca
tggCTCCTGGgca
tggcTCCTGGGca
 Created
Created
Created
N
N
N
 -0.099
-0.036
-0.075

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