SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_005628
Gene Symbol:	SLC1A5
Description:	Homo sapiens solute carrier family 1 (neutral amino acid transporter), member 5 (SLC1A5), transcript variant 2, mRNA.
Gene Location:	chr19(-):47278139-47291842
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr19:g.46775154G>T			COSN6145609		RK308_C01		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-361-3p	ccaCTGGGGGgatgttaca	0	UCCCCCAG	m7b	(m7b->m6c)	-0.589000	-0.382000	1.120000
hsa-miR-499a-3p	ccactgggGTGATGTTaca	0	AACAUCAC	m8a	Created	no TS	-0.098000	-3.060000
hsa-miR-499b-3p	ccactgggGTGATGTTaca	0	AACAUCAC	m8a	Created	no TS	-0.098000	-1.950000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
46775158	rs113044612	G	G	hsa-miR-194-3p hsa-miR-361-3p	0	CCCACTGggggga cccaCTGGGGGga	Disrupted Disrupted	N N	-0.111 -0.207
			A	hsa-miR-1296-3p hsa-miR-4727-3p	0	CCCACTAggggga CCCACTAggggga	Created Created	N N	-0.195 -0.115

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