SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001128588 |
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Gene Symbol: | SLC14A1 |
Description: | Homo sapiens solute carrier family 14 (urea transporter), member 1 (Kidd blood group) (SLC14A1), transcript variant 1, mRNA. |
Gene Location: | chr18(+):43304091-43332485 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr18:g.45751222T>C | ICGC_B0992398-2A78-11E2-8335-12FD496BB9B8 | CPCG_0102_Pr_P_P2 | ProstateCancer(OICR,CA) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3199 |
gcctgtAGTCCCagctact |
0 | AGGGACUG | m6b | Created | -0.129 | -0.127 | No effect | |
hsa-miR-365a-5p |
gcctgtAGTCCCagctact |
0 | AGGGACUU | m6b | Created | no TS | -0.008 | No effect | |
hsa-miR-365b-5p |
gcctgtAGTCCCagctact |
0 | AGGGACUU | m6b | Created | no TS | -0.008 |
-0.64 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr18:g.45751356A>C | 9_36386 | CRC-4-Tumor | Colorectal adenocarcinoma | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-5010-3p |
aaaaaaaaACACAAAcaaa |
1 |
UUUUGUGU | m7b | Created | -0.086 | -0.141 |
-3.15 |
|
hsa-miR-599 |
aaaaaaaaACACAAacaaa |
1 |
GUUGUGUC | m6b | Created | -0.067 | -0.074 |
-1.0 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr18:g.45752178G>C | COSN6124676 | RK162_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-642b-5p |
tcttgttAGGGAACgtgtg |
2 |
GGUUCCCU | m7b | Disrupted | -0.432000 | -0.198000 | No effect |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
45750829 | rs16978481 | C | C |
hsa-miR-1256 hsa-miR-3688-5p hsa-miR-4474-3p hsa-miR-7108-5p hsa-miR-891a-3p |
4 3 4 4 3 |
taAATGCCAcaaa taaaTGCCACAaa taaatGCCACAAa taaatGCCACAAa taaaTGCCACAaa |
Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N |
-0.073 -0.131 -0.125 -0.123 -0.123 |
A |
hsa-miR-4729 hsa-miR-5010-3p hsa-miR-5696 hsa-miR-592 hsa-miR-597-5p hsa-miR-599 hsa-miR-616-3p |
5 4 5 3 3 4 4 |
TAAATGAcacaaa taaatgACACAAA TAAATGAcacaaa taaaTGACACAAa taaaTGACACAaa taaatGACACAAA taAATGACAcaaa |
Created Created Created Created Created Created Created |
N N N N N N N |
0.081 -0.025 0.057 -0.23 -0.088 -0.202 -0.013 |