SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001031702
Gene Symbol: SEMA5B
Description: Homo sapiens sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (SEMA5B), transcript variant 1, mRNA.
Gene Location: chr3(-):122628042-122746576
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr3:g.122909255G>A COSN8488048 227_T [lung][NS][carcinoma][squamous_cell_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-20b-3p tcacaatttACTACAGcaa
 0 ACUGUAGU m7b (m6b->m7b) no TS -0.210000 -0.010000
hsa-miR-3137 tcacaatttGCTACAGcaa
 13
 UCUGUAGC m7b (m7b->m6b) -0.264000 no TS -0.010000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.122909282T>A ICGC_733730B2-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-147a cacacacaCACACACacgc
 0 GUGUGUGG m7a Created -0.098 -0.098 -0.12
hsa-miR-4658 cacacACACTCACacacgc
 0 GUGAGUGU m8a Disrupted -0.139 no TS 0.64
hsa-miR-4758-5p cacacaCACTCACacacgc
 0 GUGAGUGG m7a Disrupted NA NA 15.75
hsa-miR-574-5p cacaCACACTCAcacacgc
 0 UGAGUGUG m8a Disrupted -0.449 no TS -3.22

Mutation Mutation ID Sample Name Cancer Type
chr3:g.122909741C>T COSN1266401 HX10T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1207-3p ggccttctCCAGCTGgccc
 2
 UCAGCUGG m7b Disrupted -0.108000 no TS 0.230000
hsa-miR-1253 ggcCTTCTCTagctggccc
 0 AGAGAAGA m7a (m6b->m7a) NA NA -0.340000
hsa-miR-3123 ggccTTCTCTagctggccc
 0 CAGAGAAU m6b Created no TS 0.025000 -0.030000
hsa-miR-3135b ggccttCTCCAGCtggccc
 2
 GGCUGGAG m7b Disrupted -0.146000 no TS 0.010000
hsa-miR-3925-5p ggccTTCTCTagctggccc
 0 AAGAGAAC m6b Created no TS 0.018000 -0.020000
hsa-miR-4434 ggcCTTCTCCagctggccc
 2
 AGGAGAAG m7b (m7b->m6c) -0.122000 no TS 2.130000
hsa-miR-4516 ggcCTTCTCCagctggccc
 2
 GGGAGAAG m7b (m7b->m6c) -0.101000 no TS 2.260000
hsa-miR-4531 ggccTTCTCCAgctggccc
 2
 AUGGAGAA m7b Disrupted 0.011000 no TS 2.330000
hsa-miR-5703 ggcCTTCTCCagctggccc
 2
 AGGAGAAG m7b (m7b->m6c) -0.122000 no TS 2.560000
hsa-miR-1207-3p ggccttctCCAGCTGgccc
 0 UCAGCUGG m7b Disrupted -0.108 no TS 0.23
hsa-miR-1253 ggcCTTCTCTagctggccc
 0 AGAGAAGA m7a (m6b->m7a) NA NA -0.34
hsa-miR-3123 ggccTTCTCTagctggccc
 0 CAGAGAAU m6b Created no TS 0.025 -0.03
hsa-miR-3135b ggccttCTCCAGCtggccc
 0 GGCUGGAG m7b Disrupted -0.146 no TS 0.01
hsa-miR-3925-5p ggccTTCTCTagctggccc
 0 AAGAGAAC m6b Created no TS 0.018 -0.02
hsa-miR-4434 ggcCTTCTCCagctggccc
 0 AGGAGAAG m7b (m7b->m6c) -0.122 no TS 2.13
hsa-miR-4516 ggcCTTCTCCagctggccc
 0 GGGAGAAG m7b (m7b->m6c) -0.101 no TS 2.26
hsa-miR-4531 ggccTTCTCCAgctggccc
 0 AUGGAGAA m7b Disrupted 0.011 no TS 2.33
hsa-miR-5703 ggcCTTCTCCagctggccc
 0 AGGAGAAG m7b (m7b->m6c) -0.122 no TS 2.56

Mutation Mutation ID Sample Name Cancer Type
chr3:g.122909918G>T COSN6748080 RK308_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3661 ttcagcCCAGGTCtctcat
 12
 UGACCUGG m7b Disrupted -0.193000 no TS No effect
hsa-miR-378g ttcAGCCCAGgtctctcat
 11
 ACUGGGCU m7b (m7b->m6c) -0.141000 no TS 0.020000
hsa-miR-631 ttcagcCCAGGTCTctcat
 12
 AGACCUGG m8a Disrupted -0.193000 no TS No effect
hsa-miR-769-5p ttcagcccAGGTCTCtcat
 12
 UGAGACCU m7b Disrupted -0.128000 no TS 0.140000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.122910024G>A COSN1266402 HCC132T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4708-3p tgctGCCTTGCctgtgggg
 4
 AGCAAGGC m7b Disrupted -0.382000 -0.175000 13.360000
hsa-miR-4742-5p tgctgccTTGCCTGtgggg
 4
 UCAGGCAA m7b Disrupted -0.063000 no TS 0.530000
hsa-miR-4708-3p tgctGCCTTGCctgtgggg
 4
 AGCAAGGC m7b Disrupted -0.382000 -0.175000 13.360000
hsa-miR-4742-5p tgctgccTTGCCTGtgggg
 4
 UCAGGCAA m7b Disrupted -0.063000 no TS 0.530000
hsa-miR-4708-3p tgctGCCTTGCctgtgggg
 0 AGCAAGGC m7b Disrupted -0.382 -0.175 13.36
hsa-miR-4742-5p tgctgccTTGCCTGtgggg
 0 UCAGGCAA m7b Disrupted -0.063 no TS 0.53

Mutation Mutation ID Sample Name Cancer Type
chr3:g.122910058C>T COSN9735790 C0062T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3148 tttggtTTTTTCCctctgc
 0 UGGAAAAA m7b Created no TS -0.024000 -4.210000
hsa-miR-4419a tttggttttCTCCCTCtgc
 5
 UGAGGGAG m7b (m7b->m6b) -0.232000 no TS 1.700000
hsa-miR-4510 tttggttttCTCCCTCtgc
 5
 UGAGGGAG m7b (m7b->m6b) -0.223000 no TS 0.350000
hsa-miR-4668-5p tttggttTTTTCCCTctgc
 0 AGGGAAAA m8a Created no TS -0.125000 -2.820000
hsa-miR-548aa ttTGGTTTTTtccctctgc
 7
 AAAAACCA m8a (m7b->m8a) -0.054000 -0.081000 -0.030000
hsa-miR-548ac tttGGTTTTTtccctctgc
 0 CAAAAACC m7b (m6c->m7b) no TS -0.032000 2.540000
hsa-miR-548ap-3p ttTGGTTTTTtccctctgc
 7
 AAAAACCA m8a (m7b->m8a) -0.054000 -0.081000 -0.030000
hsa-miR-548d-3p tttGGTTTTTtccctctgc
 0 CAAAAACC m7b (m6c->m7b) no TS -0.041000 -1.570000
hsa-miR-548h-3p tttGGTTTTTtccctctgc
 0 CAAAAACC m7b (m6c->m7b) no TS -0.032000 1.040000
hsa-miR-548t-3p ttTGGTTTTTtccctctgc
 7
 AAAAACCA m8a (m7b->m8a) -0.054000 -0.081000 -0.030000
hsa-miR-548z tttGGTTTTTtccctctgc
 0 CAAAAACC m7b (m6c->m7b) no TS -0.032000 1.040000
hsa-miR-5584-5p tttggtttTTTCCCTctgc
 0 CAGGGAAA m7b Created no TS -0.150000 1.260000

Mutation Mutation ID Sample Name Cancer Type
chr3:g.122910059T>A COSN9735791 C0062T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-548aa gttTGGTTTTctccctctg
 7
 AAAAACCA m7b (m7b->m6c) -0.054000 no TS -0.170000
hsa-miR-548ap-3p gttTGGTTTTctccctctg
 7
 AAAAACCA m7b (m7b->m6c) -0.054000 no TS -5.270000
hsa-miR-548t-3p gttTGGTTTTctccctctg
 7
 AAAAACCA m7b (m7b->m6c) -0.054000 no TS -0.170000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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