SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_014302
Gene Symbol:	SEC61G
Description:	Homo sapiens Sec61 gamma subunit (SEC61G), transcript variant 2, mRNA.
Gene Location:	chr7(-):54819939-54826939
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Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr7:g.54752301T>-			ICGC_ssm_v3_106400		HCC4T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-3148	tttttTTTTTCCtttcaag	0	UGGAAAAA	m7b	Disrupted	-0.124000	-0.118000	1.080000
hsa-miR-488-3p	tttttttttCCTTTCAAg	0	UUGAAAGG	m8a	(m7a->m8a)	-0.336000	-0.336000	0.700000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
54752298	rs1802301	T	T	hsa-miR-488-3p hsa-miR-5681a hsa-miR-651-3p hsa-miR-6730-5p	2 2 3 2	ttttCCTTTCAAg ttttCCTTTCAag tTTTCCTTtcaag ttttCCTTTCAag	Disrupted Disrupted Disrupted Disrupted	N N N N	-0.336 -0.14 -0.169 -0.143
			C	hsa-miR-3179 hsa-miR-4635 hsa-miR-4668-5p hsa-miR-5584-5p hsa-miR-6126 hsa-miR-6864-5p hsa-miR-7515	2 2 3 3 2 2 2	ttttCCCTTCAag ttttccCTTCAAG TTTTCCCttcaag tTTTCCCTtcaag ttttcCCTTCAAg ttttCCCTTCAAg tttTCCCTTCAag	Created Created Created Created Created Created Created	N N N N N N N	-0.193 -0.217 -0.259 -0.239 -0.151 -0.46 -0.455
54752305	rs188393294	T	T	hsa-miR-3148	21	ttttttTTTTTCC	Disrupted	N	-0.124
			C	hsa-miR-6124	21	ttttttCTTTTCC	Created	N	-0.187

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