SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_006987 |
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Gene Symbol: | RPH3AL |
Description: | Homo sapiens rabphilin 3A-like (without C2 domains) (RPH3AL), transcript variant 2, mRNA. |
Gene Location: | chr17(-):62179-202633 |
Browse Associations |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr17:g.212855G>A | COSN6659607 | CHC205T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3140-5p |
aagagcagcATTCAGGTgc |
3 |
ACCUGAAU | m8a | (m7a->m8a) | -0.069000 | -0.070000 |
-1.720000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr17:g.213089A>T | ICGC_AF26E2F2-2A78-11E2-8335-12FD496BB9B8 | CPCG_0102_Pr_P_P2 | ProstateCancer(OICR,CA) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1236 |
tatttttaGAAGAGatggg |
0 | CCUCUUCC | m6b | Disrupted | -0.04 | -0.02 |
0.55 |
|
hsa-miR-3675-3p |
tatttttagTAGAGATGgg |
0 | CAUCUCUA | m8a | (m7a->m8a) | no TS | -0.006 | No effect | |
hsa-miR-4684-5p |
tatttttaGTAGAGAtggg |
0 | CUCUCUAC | m7b | Created | no TS | -0.108 |
-4.75 |
|
hsa-miR-4799-5p |
tattTTTAGAagagatggg |
0 | AUCUAAAU | m6b | Disrupted | 0.055 | no TS |
0.21 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr17:g.213306G>A | COSN6659703 | CHC433T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr17:g.213327C>T | COSN9672407 | C0021T | [kidney][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-149-3p |
cccCCCTCCCatgggctgg |
0 | AGGGAGGG | m7b | (m7b->m6c) | -1.167000 | -0.955000 | No effect |
hsa-miR-30b-3p |
ccccCCTCCCAtgggctgg |
0 | CUGGGAGG | m7b | Disrupted | -0.392000 | -0.387000 | No effect |
hsa-miR-3689a-3p |
ccccCCTCCCAtgggctgg |
0 | CUGGGAGG | m7b | Disrupted | -0.422000 | -0.426000 | No effect |
hsa-miR-3689b-3p |
ccccCCTCCCAtgggctgg |
0 | CUGGGAGG | m7b | Disrupted | -0.422000 | -0.426000 | No effect |
hsa-miR-3689c |
ccccCCTCCCAtgggctgg |
0 | CUGGGAGG | m7b | Disrupted | -0.422000 | -0.426000 | No effect |
hsa-miR-4266 |
ccccCCTCCTAtgggctgg |
0 | CUAGGAGG | m7b | Created | no TS | -0.040000 | No effect |
hsa-miR-4641 |
cccccctccCATGGGCtgg |
1 |
UGCCCAUG | m7b | (m7b->m6b) | -0.193000 | -0.157000 | No effect |
hsa-miR-4695-5p |
ccccCCTCCTatgggctgg |
2 |
CAGGAGGC | m6b | Created | -0.258000 | -0.303000 | No effect |
hsa-miR-4728-5p |
cccCCCTCCCAtgggctgg |
0 | UGGGAGGG | m8a | Disrupted | -1.229000 | -1.006000 | No effect |
hsa-miR-4779 |
cccCCCTCCTAtgggctgg |
0 | UAGGAGGG | m8a | Created | no TS | -0.158000 | No effect |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
212681 | rs57752884 | C | C |
hsa-miR-1273h-5p hsa-miR-149-3p hsa-miR-2392 hsa-miR-30b-3p hsa-miR-3689a-3p hsa-miR-3689b-3p hsa-miR-3689c hsa-miR-4728-5p hsa-miR-6779-5p hsa-miR-6780a-5p hsa-miR-6785-5p hsa-miR-6799-5p hsa-miR-6871-5p hsa-miR-6883-5p hsa-miR-7106-5p |
2 2 5 2 2 2 2 2 2 2 2 2 3 2 2 |
cCCTCCCAtcctt CCCTCCCAtcctt ccctcCCATCCTt cCCTCCCAtcctt cCCTCCCAtcctt cCCTCCCAtcctt cCCTCCCAtcctt CCCTCCCAtcctt cCCTCCCAtcctt cCCTCCCAtcctt CCCTCCCAtcctt cCCTCCCAtcctt ccCTCCCATcctt CCCTCCCAtcctt cCCTCCCAtcctt |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N N N N N N N |
-0.1 -0.319 -0.102 -0.128 -0.156 -0.156 -0.156 -0.361 -0.109 -0.118 -0.382 -0.126 -0.082 -0.361 -0.13 |
T |
hsa-miR-4266 hsa-miR-4695-5p hsa-miR-4779 hsa-miR-5191 |
2 2 2 3 |
cCCTCCTAtcctt cCCTCCTAtcctt CCCTCCTAtcctt ccctCCTATCCtt |
Created Created Created Created |
N N N N |
-0.116 -0.114 -0.339 -0.19 |
|||
212855 | rs9907477 | - | |||||||
A |
hsa-miR-3140-5p |
0 |
agcagcATTCAGG |
Unknown |
N |
-0.001 |
|||
213326 | rs11150886 | - | A |
hsa-miR-1273h-5p hsa-miR-149-3p hsa-miR-30b-3p hsa-miR-3689a-3p hsa-miR-3689b-3p hsa-miR-3689c hsa-miR-4641 hsa-miR-4728-5p hsa-miR-6779-5p hsa-miR-6780a-5p hsa-miR-6785-5p hsa-miR-6799-5p hsa-miR-6871-5p hsa-miR-6883-5p hsa-miR-7106-5p |
0 |
CCTCCCAtgggct CCTCCCAtgggct CCTCCCAtgggct CCTCCCAtgggct CCTCCCAtgggct CCTCCCAtgggct cctccCATGGGCt CCTCCCAtgggct CCTCCCAtgggct CCTCCCAtgggct CCTCCCAtgggct CCTCCCAtgggct cCTCCCATgggct CCTCCCAtgggct CCTCCCAtgggct |
Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown |
N N N N N N N N N N N N N N N |
-0.033 -0.159 -0.005 0.004 0.004 0.004 -0.036 -0.161 -0.024 -0.014 -0.157 -0.055 -0.009 -0.156 -0.049 |