SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_002925
Gene Symbol: RGS10
Description: Homo sapiens regulator of G-protein signaling 10 (RGS10), transcript variant 1, mRNA.
Gene Location: chr10(-):121259338-121296045
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr10:g.119500054G>A COSN4891882 PCSI_0044_Pa_P [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3622b-5p ctcaggaCCATGCCgggtt
 0 AGGCAUGG m7b Created no TS -0.240000 -1.250000
hsa-miR-4304 ctcaggacCATGCCGGgtt
 0 CCGGCAUG m8a Created no TS -0.275000 -0.050000
hsa-miR-564 ctcaggaCCGTGCCgggtt
 1
 AGGCACGG m7b Disrupted -0.311000 no TS 4.850000
hsa-miR-3622b-5p ctcaggaCCATGCCgggtt
 0 AGGCAUGG m7b Created no TS -0.240000 -1.250000
hsa-miR-4304 ctcaggacCATGCCGGgtt
 0 CCGGCAUG m8a Created no TS -0.275000 -0.050000
hsa-miR-564 ctcaggaCCGTGCCgggtt
 1
 AGGCACGG m7b Disrupted -0.311000 no TS 4.850000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
119500054 rs184862536 G G hsa-miR-564
1
 aggaCCGTGCCgg
 Disrupted
N
 -0.311
T hsa-miR-6809-5p
1
 aggaCCTTGCCgg
 Created
N
 -0.276

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