SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_002874 |
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Gene Symbol: | RAD23B |
Description: | Homo sapiens RAD23 homolog B (S. cerevisiae) (RAD23B), transcript variant 2, mRNA. |
Gene Location: | chr9(+):110045543-110094470 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.107329693C>T | COSN9275043 | C0088T | [kidney][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-2054 |
acaccagtgTATTACActa |
0 | CUGUAAUA | m7b | (m6c->m7b) | no TS | -0.053000 |
-0.090000 |
|
hsa-miR-374c-5p |
acaccagTGTATTAcacta |
10 |
AUAAUACA | m7b | Created | 0.014000 | -0.057000 |
-0.660000 |
|
hsa-miR-501-3p |
acaccaGTGCATTacacta |
0 | AAUGCACC | m7a | Disrupted | NA | NA |
0.080000 |
|
hsa-miR-502-3p |
acaccaGTGCATTacacta |
0 | AAUGCACC | m7a | Disrupted | NA | NA |
0.240000 |
|
hsa-miR-655 |
acaccagTGTATTAcacta |
10 |
AUAAUACA | m7b | Created | 0.032000 | -0.020000 |
-1.750000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.107329821A>T | COSN8519771 | 1848_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-144-3p |
gataaATACTGTgcatgtc |
0 | UACAGUAU | m7b | Created | -0.156000 | -0.263000 | No effect | |
hsa-miR-16-1-3p |
gataAATACTGtgcatgtc |
0 | CCAGUAUU | m7b | Created | no TS | -0.120000 |
-4.570000 |
|
hsa-miR-4742-3p |
gataAATACAGtgcatgtc |
0 | UCUGUAUU | m7b | Disrupted | -0.117000 | no TS |
0.310000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.107331152G>A | COSN9694288 | AOCS-139-19-0 | [ovary][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1279 |
tttagcaCAATATGgtgat |
0 | UCAUAUUG | m7b | Created | no TS | 0.019000 |
-1.360000 |
|
hsa-miR-4318 |
tttagCACAGTatggtgat |
1 |
CACUGUGG | m6b | Disrupted | -0.046000 | no TS |
0.270000 |
|
hsa-miR-4693-5p |
tttagCACAGTATggtgat |
1 |
AUACUGUG | m8a | Disrupted | -0.025000 | no TS |
0.010000 |
|
hsa-miR-5008-3p |
tttAGCACAGtatggtgat |
11 |
CCUGUGCU | m7b | (m7b->m6b) | -0.219000 | -0.078000 |
6.520000 |
|
hsa-miR-892a |
tttagCACAGTatggtgat |
12 |
CACUGUGU | m6b | Disrupted | -0.190000 | -0.145000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.107331245A>G | ICGC_A62D34A8-2A78-11E2-8335-12FD496BB9B8 | CPCG_0102_Pr_P_P2 | ProstateCancer(OICR,CA) | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1295b-3p |
ctcatGCCTATaatcccag |
1 |
AAUAGGCC | m6b | Disrupted | -0.051 | no TS |
0.07 |
|
hsa-miR-4423-3p |
ctcaTGCCTATaatcccag |
0 | AUAGGCAC | m7a | Disrupted | NA | NA | No effect | |
hsa-miR-4438 |
ctcatGCCTGTaatcccag |
0 | CACAGGCU | m6b | Created | no TS | -0.032 | No effect | |
hsa-miR-4514 |
ctcaTGCCTGTaatcccag |
0 | ACAGGCAG | m7a | Created | NA | NA | No effect | |
hsa-miR-5095 |
ctcatGCCTGTAAtcccag |
0 | UUACAGGC | m8a | Created | no TS | -0.17 |
-0.1 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.107331689C>A | COSN9974986 | PTC-73C | [thyroid][NS][other][neoplasm] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-129-5p |
aactggaaaCAAAAAaaaa |
0 | CUUUUUGC | m6b | Disrupted | 0.181000 | 0.122000 |
0.030000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.107331854A>G | COSN5117830 | HX31T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-345-5p |
tcttaaaGAGTCAGCcgag |
3 |
GCUGACUC | m8a | Created | -0.060000 | -0.253000 |
-5.950000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr9:g.107331916A>G | COSN1371488 | HCC73T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-450b-5p |
gtttaatTTGCAAActgtt |
0 | UUUUGCAA | m7b | Created | no TS | -0.136000 | No effect | |
hsa-miR-518a-5p |
gtttaaTTTGCAaactgtt |
0 | CUGCAAAG | m6b | Created | no TS | -0.068000 |
0.240000 |
|
hsa-miR-527 |
gtttaaTTTGCAaactgtt |
0 | CUGCAAAG | m6b | Created | no TS | -0.068000 |
0.240000 |
|
hsa-miR-548aw |
gtttaaTTTGCAaactgtt |
15 |
GUGCAAAA | m6b | Created | -0.160000 | -0.228000 |
-0.050000 |
|
hsa-miR-450b-5p |
gtttaatTTGCAAActgtt |
0 | UUUUGCAA | m7b | Created | no TS | -0.136000 | No effect | |
hsa-miR-518a-5p |
gtttaaTTTGCAaactgtt |
0 | CUGCAAAG | m6b | Created | no TS | -0.068000 |
0.240000 |
|
hsa-miR-527 |
gtttaaTTTGCAaactgtt |
0 | CUGCAAAG | m6b | Created | no TS | -0.068000 |
0.240000 |
|
hsa-miR-548aw |
gtttaaTTTGCAaactgtt |
15 |
GUGCAAAA | m6b | Created | -0.160000 | -0.228000 |
-0.050000 |
|
hsa-miR-450b-5p |
gtttaatTTGCAAActgtt |
0 | UUUUGCAA | m7b | Created | no TS | -0.136 | No effect | |
hsa-miR-518a-5p |
gtttaaTTTGCAaactgtt |
0 | CUGCAAAG | m6b | Created | no TS | -0.068 |
0.24 |
|
hsa-miR-527 |
gtttaaTTTGCAaactgtt |
0 | CUGCAAAG | m6b | Created | no TS | -0.068 |
0.24 |
|
hsa-miR-548aw |
gtttaaTTTGCAaactgtt |
0 | GUGCAAAA | m6b | Created | -0.16 | -0.228 |
-0.05 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr9:g.107331929G>T | COSN8117120 | 8036161 | [pancreas][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-495 |
actgtTTTGTTaaatctct |
0 | AAACAAAC | m6b | Created | no TS | -0.001000 |
-2.250000 |
hsa-miR-5688 |
actgtTTTGTTAaatctct |
0 | UAACAAAC | m7a | Created | no TS | -0.022000 |
-6.280000 |
hsa-miR-7-1-3p |
actgtTTTGTTaaatctct |
0 | CAACAAAU | m6b | Created | no TS | -0.007000 |
-0.290000 |
hsa-miR-7-2-3p |
actgtTTTGTTaaatctct |
0 | CAACAAAU | m6b | Created | no TS | -0.004000 |
-0.170000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
107331242 | rs11573730 | C | C |
hsa-miR-1295b-3p |
1 |
ctcatGCCTATAa |
Disrupted |
N |
-0.051 |
107331523 | rs149796946 | A | A |
hsa-miR-586 hsa-miR-6076 hsa-miR-640 hsa-miR-6797-3p |
5 8 7 8 |
tggatcATGCATA tggaTCATGCAta TGGATCAtgcata tggaTCATGCAta |
Disrupted Disrupted Disrupted Disrupted |
N N N N |
-0.055 -0.108 -0.176 -0.112 |
G |
hsa-miR-501-3p hsa-miR-502-3p |
5 5 |
tggatcGTGCATA tggatcGTGCATA |
Created Created |
N N |
-0.122 -0.122 |
|||
107331689 | rs74357018 | C | C |
hsa-miR-129-5p |
3 |
tggaaaCAAAAAA |
Disrupted |
N |
0.059 |
107331690 | rs201461138 | - | AAA |
hsa-miR-129-5p |
2 |
ctggaaaCAAAAAAaaa |
Unknown |
N |
-0.01 |
- | |||||||||
107331690 | rs5899731 | - | A |
hsa-miR-129-5p |
3 |
ggaaaCAAAAAAa |
Unknown |
N |
-0.003 |
- |