| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_018292 |
|---|---|
| Gene Symbol: | QRSL1 |
| Description: | Homo sapiens glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 (QRSL1), mRNA. |
| Gene Location: | chr6(+):107077440-107116292 |
| Browse Associations | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr6:g.106666165A>G | COSN9289526 | AOCS-109-1-X | [ovary][NS][other][neoplasm] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3190-5p |
acaaaaatTGGCCAGgctt |
0 | UCUGGCCA | m7b | Created | no TS | -0.252000 |
-6.190000 |
|
| hsa-miR-4735-5p |
acaaAAATTAGccaggctt |
1 |
CCUAAUUU | m7b | Disrupted | -0.012000 | no TS |
0.050000 |
|
| hsa-miR-4775 |
acaAAAATTAgccaggctt |
2 |
UUAAUUUU | m7b | (m7b->m6b) | 0.000000 | 0.000000 |
0.020000 |
|
| hsa-miR-4794 |
acaaaaatTAGCCAGgctt |
1 |
UCUGGCUA | m7b | Disrupted | -0.224000 | -0.042000 |
1.290000 |
|
| hsa-miR-548s |
acaaaaaTTGGCCAggctt |
0 | AUGGCCAA | m7b | Created | no TS | -0.213000 |
-5.540000 |
|
| hsa-miR-664-5p |
acaaaaatTAGCCAGgctt |
1 |
ACUGGCUA | m7b | Disrupted | -0.267000 | -0.048000 |
1.120000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr6:g.106666486A>G | COSN14786367 | CHC205T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-105-5p |
tcaGCATTTGgtaagcatc |
0 | UCAAAUGC | m7b | (m6b->m7b) | no TS | -0.110000 |
-1.930000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr6:g.106666760C>T | COSN6719937 | RK123_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-106b-3p |
aattgAGTGCGattattgg |
0 | CCGCACUG | m6b | Disrupted | -0.199000 | no TS |
6.310000 |
|
| hsa-miR-34b-3p |
aattgagtGTGATTattgg |
0 | CAAUCACU | m6b | Created | no TS | 0.005000 |
-7.470000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr6:g.106667519A>G | COSN14794412 | CHC205T | [liver][NS][carcinoma][hepatocellular_carcinoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4452 |
ttacttaatGAATTCActt |
0 | UUGAAUUC | m7b | (m6c->m7b) | no TS | -0.096000 | No effect | |
| hsa-miR-4477a |
ttaCTTAATAaattcactt |
0 | CUAUUAAG | m7b | (m7b->m6b) | 0.028000 | 0.047000 | No effect | |
| hsa-miR-4760-3p |
ttacttaATGAATTcactt |
0 | AAAUUCAU | m7b | Created | -0.094000 | -0.119000 |
-0.020000 |
|
| hsa-miR-664-3p |
ttacttAATGAATtcactt |
2 |
UAUUCAUU | m7b | Created | -0.046000 | -0.060000 |
-1.170000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr6:g.106667820G>A | COSN7781346 | PCSI_0164_Pa_P_526 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-224-3p |
gaggaaACCATTTTaagtt |
2 |
AAAAUGGU | m8a | Created | -0.027000 | -0.137000 |
-0.480000 |
|
| hsa-miR-29b-2-5p |
gagGAAACCAttttaagtt |
2 |
CUGGUUUC | m7b | (m6b->m7b) | -0.096000 | -0.209000 |
-0.110000 |
|
| hsa-miR-3662 |
gaggaaacCATTTTaagtt |
8 |
GAAAAUGA | m6b | Created | 0.049000 | 0.116000 | No effect | |
| hsa-miR-424-3p |
gaggaaacCGTTTTaagtt |
0 | CAAAACGU | m6b | Disrupted | -0.073000 | no TS |
1.240000 |
|
| hsa-miR-522-3p |
gaggaaACCATTTTaagtt |
2 |
AAAAUGGU | m8a | Created | -0.041000 | -0.161000 |
-0.720000 |
|
| hsa-miR-548ad |
gaggaaacCGTTTTaagtt |
0 | GAAAACGA | m6b | Disrupted | -0.066000 | no TS |
9.260000 |
|
| hsa-miR-553 |
gaggaaACCGTTTTaagtt |
0 | AAAACGGU | m8a | Disrupted | -0.244000 | no TS |
5.540000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr6:g.106668056C>T | ICGC_534218 | TCGA-AA-3555-01A-01W-0831-10 | ColonAdenocarcinoma(TCGA,US) | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 106666486 | rs1026619 | A | |||||||
| G |
hsa-miR-105-5p hsa-miR-7853-5p |
5 5 |
GCATTTGgtaagc GCATTTGgtaagc |
Created Created |
N N |
-0.11 -0.082 |
|||
| 106667000 | rs149463253 | A | A |
hsa-miR-149-5p hsa-miR-3064-5p hsa-miR-4794 hsa-miR-6504-5p hsa-miR-664a-5p hsa-miR-6815-3p |
5 5 5 5 5 3 |
cctagaAGCCAGA cctagaAGCCAGA cctagaAGCCAGA cctagaAGCCAGA cctagaAGCCAGA cctAGAAGCCAga |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N |
-0.039 -0.034 -0.042 -0.034 -0.048 -0.126 |
| G |
hsa-miR-3176 hsa-miR-3190-5p hsa-miR-3922-3p hsa-miR-4757-5p hsa-miR-6744-3p hsa-miR-6878-3p |
3 5 3 3 3 3 |
cctagAGGCCAGA cctagaGGCCAGA cctagAGGCCAGA cctAGAGGCCAga cctAGAGGCCAga cctaGAGGCCAga |
Created Created Created Created Created Created |
N N N N N N |
-0.167 -0.07 -0.167 -0.167 -0.209 -0.121 |
|||
| 106667519 | rs3101493 | A | A |
hsa-miR-4477a |
2 |
CTTAATAAattca |
Disrupted |
N |
-0.019 |
| G |
hsa-miR-4452 hsa-miR-4760-3p hsa-miR-664a-3p |
6 5 5 |
cttaatGAATTCA cttaATGAATTca cttAATGAATtca |
Created Created Created |
N N N |
-0.096 -0.025 -0.014 |