SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001098503
Gene Symbol: PTPRJ
Description: Homo sapiens protein tyrosine phosphatase, receptor type, J (PTPRJ), transcript variant 2, mRNA.
Gene Location: chr11(+):48002109-48154266
Browse Associations
Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr11:g.48132598T>C ICGC_8436D3A4-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4636 tgtaaatgACGAGTTaatg
 0 AACUCGUG m7a Created NA NA -6.81

Mutation Mutation ID Sample Name Cancer Type
chr11:g.48132617C>A ICGC_A8AB75F0-2A78-11E2-8335-12FD496BB9B8 CPCG_0102_Pr_P_P2 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-29b-2-5p ggtgcagcAAACCAacatg
 0 CUGGUUUC m6b Created no TS -0.045 No effect
hsa-miR-3650 ggtgcagCACACCaacatg
 1
 AGGUGUGU m6b Disrupted -0.159 no TS 4.67
hsa-miR-5087 ggtgcagCAAACCaacatg
 0 GGGUUUGU m6b Created -0.19 -0.301 -1.56

Mutation Mutation ID Sample Name Cancer Type
chr11:g.48132648A>T ICGC_C66A4F3A-2A78-11E2-BDED-1EFD496BB9B8 CPCG_0103_Pr_P_P4 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4464 atatgtaaCAAACCTgcac
 0 AAGGUUUG m7b Disrupted -0.192 no TS 5.48
hsa-miR-4748 atatgtaaCAAACCTgcac
 0 GAGGUUUG m7b Disrupted -0.173 no TS 4.61
hsa-miR-5087 atatgtaACAAACCtgcac
 1
 GGGUUUGU m7b Disrupted -0.19 no TS 6.82


Mutation Mutation ID Sample Name Cancer Type
chr11:g.48132658G>A ICGC_8436D8A4-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr11:g.48132677G>A ICGC_A8AB7FA0-2A78-11E2-8335-12FD496BB9B8 CPCG_0102_Pr_P_P2 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-148a-5p tgtaccctAGAACTTaaag
 0 AAAGUUCU m7b Disrupted -0.315 no TS -3.55
hsa-miR-148b-5p tgtaccctAGAACTTaaag
 0 AAGUUCUG m7a Disrupted NA NA -3.99
hsa-miR-2909 tgtaCCCTAAaacttaaag
 0 GUUAGGGC m6b Created no TS -0.183 No effect
hsa-miR-3168 tgtacccTAGAACTtaaag
 1
 GAGUUCUA m7b Disrupted -0.157 no TS No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Germline mutations in target sites of miRNAs in somatic mutation table
Location SNP ID Ancestral
Allele		 Allele miR ID Conservation miRSite FuncClass Validation context+
score change
48132683 rs35644484 - - hsa-miR-148a-5p
1
 GAACTTAaagtat
 Unknown
N
 0.003
A hsa-miR-5003-3p
hsa-miR-7856-5p
1
1
 gaacttAAAAGTAt
gaaCTTAAAAgtat
 Unknown
Unknown
N
N
 -0.049
-0.02

Genome Browser