SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
  Home Search Help Download  

PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001145368
Gene Symbol: PTPN3
Description: Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 2, mRNA.
Gene Location: chr9(-):112137973-112260593
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr9:g.109376763C>G COSN15062754 LP6005500-DNA_B01 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3974 ctgtttcacGACCTTatac
 1
 AAAGGUCA m6b Created -0.211000 -0.268000 -0.010000
hsa-miR-431-3p ctgtttcACGACCTtatac
 0 CAGGUCGU m7b Created no TS -0.255000 -9.890000
hsa-miR-4735-3p ctgtttcacCACCTTatac
 0 AAAGGUGC m6b Disrupted -0.053000 no TS 0.220000


Mutation Mutation ID Sample Name Cancer Type
chr9:g.109377001A>G COSN2305173 RK041_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr9:g.109377570A>G ICGC_81541886-2A78-11E2-96E7-04FD496BB9B8 CPCG_0102_Pr_P_P1 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1273g-3p ggctggagtGCAGTGGcat
 0 ACCACUGC m7b (m6b->m7b) -0.076 -0.183 -2.02
hsa-miR-4793-3p ggctggAGTGCAGtggcat
 0 UCUGCACU m7b Created no TS 0.084 0.05
hsa-miR-508-5p ggCTGGAGTAcagtggcat
 0 UACUCCAG m8a (m8a->m7b) 0.058 0.083 2.47

Mutation Mutation ID Sample Name Cancer Type
chr9:g.109377869G>A COSN4885597 tumor_4189200 [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1268a agttcctACGCCCactcag
 1
 CGGGCGUG m6b Disrupted -0.065000 no TS 1.750000
hsa-miR-1268b agttcctACGCCCactcag
 1
 CGGGCGUG m6b Disrupted -0.065000 no TS 1.750000
hsa-miR-4455 agttcctACACCCactcag
 2
 AGGGUGUG m6b Created -0.285000 -0.257000 No effect
hsa-miR-585 agttccTACGCCCActcag
 1
 UGGGCGUA m8a Disrupted -0.132000 no TS 2.680000
hsa-miR-609 agttcctACACCCactcag
 2
 AGGGUGUU m6b Created -0.130000 -0.127000 -0.010000

Mutation Mutation ID Sample Name Cancer Type
chr9:g.109377888C>T COSN5695163 RK085_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1913 gctaaGGGGCAGgggattc
 0 UCUGCCCC m7b Disrupted -0.251000 -0.146000 0.020000
hsa-miR-3162-3p gctaaggGGTAGGGgattc
 0 UCCCUACC m7b Created no TS -0.031000 -5.120000
hsa-miR-324-3p gctaaGGGGCAGgggattc
 0 ACUGCCCC m7b Disrupted -0.242000 -0.137000 0.280000
hsa-miR-4749-3p gctaAGGGGCaggggattc
 2
 CGCCCCUC m6b Disrupted -0.032000 no TS 1.480000

Mutation Mutation ID Sample Name Cancer Type
chr9:g.109377920A>T COSN6375391 RK178_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-578 attgaaaACAAGAAaccac
 2
 CUUCUUGU m7b Disrupted 0.264000 0.137000 0.800000

Mutation Mutation ID Sample Name Cancer Type
chr9:g.109379400C>T COSN1084706 TCGA-B5-A11E-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-338-5p aaaagATATTGTgtacata
 0 AACAAUAU m7b Created no TS -0.052000 -2.600000
hsa-miR-4731-3p aaaagataTTGTGTacata
 0 CACACAAG m6b Created 0.176000 0.113000 0.020000
hsa-miR-338-5p aaaagATATTGTgtacata
 0 AACAAUAU m7b Created no TS -0.052 -2.6
hsa-miR-4731-3p aaaagataTTGTGTacata
 0 CACACAAG m6b Created 0.176 0.113 0.02

Mutation Mutation ID Sample Name Cancer Type
chr9:g.109379404A>T COSN2305174 RK041_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5003-3p ataGAAAAGTtatcgtgta
 3
 UACUUUUC m7b (m6c->m7b) 0.060000 -0.092000 0.220000
hsa-miR-5003-3p ataGAAAAGTtatcgtgta
 0 UACUUUUC m7b (m6c->m7b) 0.06 -0.092 0.22

Mutation Mutation ID Sample Name Cancer Type
chr9:g.109379511C>A COSN1084705 TCGA-AP-A059-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3173-3p ggcatCCTCCTTgaaagag
 4
 AAAGGAGG m7b Disrupted -0.188000 no TS No effect
hsa-miR-3605-5p ggCATCCTCAttgaaagag
 5
 UGAGGAUG m8a (m7b->m8a) -0.267000 -0.456000 No effect
hsa-miR-4428 ggcatcCTCCTTGaaagag
 0 CAAGGAGA m7a Disrupted NA NA No effect
hsa-miR-561-5p ggcatccTCCTTGAaagag
 0 AUCAAGGA m7b Disrupted -0.265000 no TS No effect
hsa-miR-3173-3p ggcatCCTCCTTgaaagag
 0 AAAGGAGG m7b Disrupted -0.188 no TS No effect
hsa-miR-3605-5p ggCATCCTCAttgaaagag
 0 UGAGGAUG m8a (m7b->m8a) -0.267 -0.456 No effect
hsa-miR-4428 ggcatcCTCCTTGaaagag
 0 CAAGGAGA m7a Disrupted NA NA No effect
hsa-miR-561-5p ggcatccTCCTTGAaagag
 0 AUCAAGGA m7b Disrupted -0.265 no TS No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



Genome Browser