SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions
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Prediction criteria:	TargetScan sites only     All 6mer or longer seed matches

RefSeq ID:	NM_001201576
Gene Symbol:	PLSCR3
Description:	Homo sapiens phospholipid scramblase 3 (PLSCR3), transcript variant w, mRNA.
Gene Location:	chr17(-):7293046-7298162
Browse Associations

Somatic mutations that impact miRNA target sites

Mutation			Mutation ID		Sample Name		Cancer Type
chr17:g.7389899T>C			COSN1201155		HCC82T		[liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID	miRSite	Conservation	miRSeed	SeedClass	FuncClass	Wildtype CS+	Mutant CS+	PITA score change
hsa-miR-1184	atcaacaGCTGCAGGggga	0	CCUGCAGC	m8a	Disrupted	-0.204000	no TS	11.810000
hsa-miR-1301	atcaacAGCTGCAggggga	3	UUGCAGCU	m7b	Disrupted	-0.267000	-0.125000	2.870000
hsa-miR-4687-3p	atcAACAGCCgcaggggga	0	UGGCUGUU	m7b	(m6c->m7b)	no TS	-0.124000	-3.590000
hsa-miR-5047	atcaacAGCTGCAggggga	3	UUGCAGCU	m7b	Disrupted	-0.257000	-0.134000	0.450000
hsa-miR-1184	atcaacaGCTGCAGGggga	0	CCUGCAGC	m8a	Disrupted	-0.204000	no TS	11.810000
hsa-miR-1301	atcaacAGCTGCAggggga	3	UUGCAGCU	m7b	Disrupted	-0.267000	-0.125000	2.870000
hsa-miR-4687-3p	atcAACAGCCgcaggggga	0	UGGCUGUU	m7b	(m6c->m7b)	no TS	-0.124000	-3.590000
hsa-miR-5047	atcaacAGCTGCAggggga	3	UUGCAGCU	m7b	Disrupted	-0.257000	-0.134000	0.450000
hsa-miR-1184	atcaacaGCTGCAGGggga	0	CCUGCAGC	m8a	Disrupted	-0.204	no TS	11.81
hsa-miR-1301	atcaacAGCTGCAggggga	0	UUGCAGCU	m7b	Disrupted	-0.267	-0.125	2.87
hsa-miR-4687-3p	atcAACAGCCgcaggggga	0	UGGCUGUU	m7b	(m6c->m7b)	no TS	-0.124	-3.59
hsa-miR-5047	atcaacAGCTGCAggggga	0	UUGCAGCU	m7b	Disrupted	-0.257	-0.134	0.45

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.

Germline mutations in target sites of miRNAs in somatic mutation table

Location	SNP ID	Ancestral Allele	Allele	miR ID	Conservation	miRSite	FuncClass	Validation	context+ score change
7389833	rs141985122	G
			A	hsa-miR-103a-3p hsa-miR-107 hsa-miR-1301-3p hsa-miR-219b-3p hsa-miR-5047 hsa-miR-7156-3p	2 2 2 2 2 2	TGCTGCAattcct TGCTGCAattcct tGCTGCAAttcct tgctGCAATTCct tGCTGCAAttcct tGCTGCAAttcct	Created Created Created Created Created Created	N N N N N N	-0.145 -0.145 -0.152 -0.121 -0.148 -0.146
7389897	rs183751536	C	C	hsa-miR-1184 hsa-miR-1301-3p hsa-miR-4660 hsa-miR-5047 hsa-miR-6801-3p hsa-miR-6810-3p	3 3 3 3 3 3	caGCTGCAGgggg cAGCTGCAggggg cAGCTGCAggggg cAGCTGCAggggg cagctGCAGGGGg cagctGCAGGGGg	Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted	N N N N N N	-0.204 -0.142 -0.117 -0.123 -0.212 -0.24

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