SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001252226
Gene Symbol: PLK2
Description: Homo sapiens polo-like kinase 2 (PLK2), transcript variant 2, mRNA.
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr5:g.58454295T>C 13_220 SJMB032_D Medulloblastoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-185-5p aatTCTCTCCgttgagagc
 30
 UGGAGAGA m7b (m6c->m7b) no TS -0.217 -2.03
hsa-miR-421 aattctctCTGTTGAgagc
 0 AUCAACAG m7b Disrupted -0.229 -0.073 0.06
hsa-miR-4306 aatTCTCTCCgttgagagc
 30
 UGGAGAGA m7b (m6c->m7b) no TS -0.217 -2.02
hsa-miR-4644 aatTCTCTCCgttgagagc
 30
 UGGAGAGA m7b (m6c->m7b) no TS -0.245 -1.49
hsa-miR-4709-5p aattctctCTGTTGagagc
 0 ACAACAGU m6b Disrupted -0.061 no TS 3.48
hsa-miR-95 aattctctCCGTTGAgagc
 0 UUCAACGG m7b Created no TS -0.294 -1.08

Mutation Mutation ID Sample Name Cancer Type
chr5:g.58454523G>C COSN14776477 CHC205T [liver][NS][carcinoma][hepatocellular_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-23a-5p tacagGGAACCCaaaagaa
 0 GGGGUUCC m7b Created no TS -0.502000 -18.670000
hsa-miR-23b-5p tacagGGAACCCAaaagaa
 0 UGGGUUCC m8a Created no TS -0.481000 -16.540000
hsa-miR-3940-5p tacagggAACCCAaaagaa
 0 GUGGGUUG m6b Created no TS -0.150000 No effect
hsa-miR-4507 tacagggAACCCAaaagaa
 0 CUGGGUUG m6b Created no TS -0.150000 No effect
hsa-miR-642b-5p tacAGGGAACCcaaaagaa
 0 GGUUCCCU m8a Created no TS -0.197000 No effect

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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