SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001256427
Gene Symbol: PDLIM5
Description: Homo sapiens PDZ and LIM domain 5 (PDLIM5), transcript variant 2, mRNA.
Browse Associations

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr4:g.94666738A>G COSN5065342 HX35T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1277-3p tcttTCTACGTAttattca
 0 UACGUAGA m8a Created no TS -0.381000 -6.490000
hsa-miR-3668 tcttTCTACATattattca
 0 AAUGUAGA m7b Disrupted -0.212000 no TS 0.270000
hsa-miR-369-3p tctttctacGTATTATTca
 0 AAUAAUAC m8a (m7b->m8a) 0.092000 0.115000 -0.720000
hsa-miR-4517 tctttctaCATATTattca
 0 AAAUAUGA m6b Disrupted 0.026000 no TS 1.440000
hsa-miR-5583-3p tctttctaCATATTattca
 0 GAAUAUGG m6b Disrupted 0.003000 -0.020000 0.130000
hsa-miR-5692b tctttctacATATTATTca
 0 AAUAAUAU m8a (m8a->m7b) 0.023000 -0.024000 -0.160000
hsa-miR-5692c tctttctacATATTATTca
 0 AAUAAUAU m8a (m8a->m7b) 0.023000 -0.024000 -0.030000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.94667476A>C COSN9246457 AOCS-145-1-6 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-369-3p gtattagcTATTATaggta
 0 AAUAAUAC m6b Disrupted 0.092000 0.008000 0.350000
hsa-miR-374a-5p gtattagcTATTATAggta
 0 UUAUAAUA m7b Disrupted 0.082000 -0.011000 0.200000
hsa-miR-374b-5p gtattagcTATTATAggta
 0 AUAUAAUA m7b Disrupted 0.051000 -0.042000 0.040000
hsa-miR-5692b gtattagcTATTATaggta
 0 AAUAAUAU m6b Disrupted 0.023000 -0.065000 0.150000
hsa-miR-5692c gtattagcTATTATaggta
 0 AAUAAUAU m6b Disrupted 0.023000 -0.065000 0.040000
hsa-miR-610 gtaTTAGCTCttataggta
 0 UGAGCUAA m7b (m6b->m7b) no TS -0.203000 -4.150000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.94667848C>G COSN2051794 RK035_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-186-5p taatttcTTCTTTaccccc
 0 CAAAGAAU m6b Disrupted 0.033000 no TS 2.340000
hsa-miR-30a-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044000 -0.050000
hsa-miR-30b-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044000 -1.850000
hsa-miR-30c-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044000 -1.160000
hsa-miR-30d-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044000 -0.010000
hsa-miR-30e-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.053000 -0.060000
hsa-miR-186-5p taatttcTTCTTTaccccc
 0 CAAAGAAU m6b Disrupted 0.033 no TS 2.34
hsa-miR-30a-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044 -0.05
hsa-miR-30b-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044 -1.85
hsa-miR-30c-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044 -1.16
hsa-miR-30d-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044 -0.01
hsa-miR-30e-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.053 -0.06

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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