SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_001011513
Gene Symbol: PDLIM5
Description: Homo sapiens PDZ and LIM domain 5 (PDLIM5), transcript variant 2, mRNA.
Gene Location: chr4(+):95373037-95589377
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr4:g.94664155T>C COSN1083639 TCGA-AP-A0LM-01 [endometrium][NS][carcinoma][endometrioid_carcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr4:g.94664647A>G COSN8618805 SS6003314 [oesophagus][NS][carcinoma][adenocarcinoma]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-663b ggtgggtGGGCCACatgag
 0 GGUGGCCC m7b Created no TS -0.357000 -11.260000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.94664835A>G COSN5580950 RK085_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-143-5p taccACTGCACtccagcct
 2
 GGUGCAGU m7b Disrupted -0.015000 0.033000 0.010000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.94664870C>A ICGC_E94F6422-2A78-11E2-89D1-29FD496BB9B8 CPCG_0103_Pr_P_P8 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1270 ctctgTCTCCAaaaaaaaa
 0 CUGGAGAU m6b Disrupted -0.085 0 No effect
hsa-miR-129-5p ctctgtctcCAAAAAaaaa
 0 CUUUUUGC m6b Disrupted 0.102 0.111 No effect
hsa-miR-3672 ctctGTCTCAaaaaaaaaa
 0 AUGAGACU m6b Created -0.23 -0.287 No effect
hsa-miR-4524a-3p ctCTGTCTCAaaaaaaaaa
 0 UGAGACAG m8a (m7a->m8a) -0.374 -0.472 No effect
hsa-miR-4531 ctctgTCTCCAaaaaaaaa
 0 AUGGAGAA m6b Disrupted -0.033 0.047 No effect
hsa-miR-620 ctctgTCTCCAaaaaaaaa
 0 AUGGAGAU m6b Disrupted -0.082 0 No effect

Mutation Mutation ID Sample Name Cancer Type
chr4:g.94665228G>A ICGC_9C286450-2A78-11E2-8335-12FD496BB9B8 CPCG_0102_Pr_P_P2 ProstateCancer(OICR,CA)
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4438 cacGCCTGTGatcccagca
 0 CACAGGCU m7a (m7a->m6a) -0.077 -0.09 No effect
hsa-miR-450b-3p cacgcctgtGATCCCAgca
 0 UUGGGAUC m7b (m7b->m6c) -0.008 no TS 0.4
hsa-miR-5089 cacgcctgtAATCCCAgca
 0 GUGGGAUU m7b (m6c->m7b) -0.036 0.027 -0.01
hsa-miR-5095 cacGCCTGTAAtcccagca
 0 UUACAGGC m8a Created -0.379 -0.433 -0.02
hsa-miR-513a-5p cacgCCTGTGAtcccagca
 2
 UUCACAGG m7b Disrupted -0.122 -0.177 No effect
hsa-miR-638 cacgcctgtGATCCCagca
 0 AGGGAUCG m6b Disrupted -0.038 no TS 0.2
hsa-miR-769-3p cacgcctgtGATCCCAGca
 0 CUGGGAUC m8a (m8a->m7b) -0.008 no TS 1.3

Mutation Mutation ID Sample Name Cancer Type
chr4:g.94665925G>A 9_57793 CRC-6-Tumor Colorectal adenocarcinoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-136-5p ccacATGGAGacagggaaa
 11
 ACUCCAUU m6b Disrupted 0.046 no TS No effect
hsa-miR-4421 ccacatggAGACAGGgaaa
 0 ACCUGUCU m7b Disrupted 0.024 no TS 0.92
hsa-miR-5581-3p ccaCATGGAAacagggaaa
 9
 UUCCAUGC m7a (m6a->m7a) no TS 0.03 No effect
hsa-miR-5699 ccacatggAGACAGGgaaa
 0 UCCUGUCU m7b Disrupted -0.004 no TS 0.04
hsa-miR-587 ccacATGGAAAcagggaaa
 10
 UUUCCAUA m7a Created -0.052 0.039 -0.01

Mutation Mutation ID Sample Name Cancer Type
chr4:g.94665976T>C COSN7849062 8068548 [pancreas][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1229 tttgcccaGTGAGAaaaca
 10
 CUCUCACC m6b Disrupted 0.033000 no TS 0.020000
hsa-miR-1304-3p tttgccCAGTGAGAaaaca
 8
 UCUCACUG m8a Disrupted 0.086000 0.027000 No effect
hsa-miR-181b-3p tttgccCAGTGAGaaaaca
 0 CUCACUGA m7a Disrupted NA NA 1.490000
hsa-miR-612 ttTGCCCAGCgagaaaaca
 5
 GCUGGGCA m8a (m7a->m8a) -0.060000 -0.032000 -0.490000
hsa-miR-720 tttgccCAGCGAGAaaaca
 0 UCUCGCUG m8a Created no TS -0.115000 -1.530000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.94666738A>G COSN5065342 HX35T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1277-3p tcttTCTACGTAttattca
 0 UACGUAGA m8a Created no TS -0.183000 -6.490000
hsa-miR-3668 tcttTCTACATattattca
 3
 AAUGUAGA m7b Disrupted -0.014000 no TS 0.280000
hsa-miR-369-3p tctttctacGTATTATTca
 2
 AAUAAUAC m8a (m7b->m8a) 0.230000 0.362000 -0.540000
hsa-miR-4517 tctttctaCATATTattca
 3
 AAAUAUGA m6b Disrupted 0.111000 no TS 1.400000
hsa-miR-5583-3p tctttctaCATATTattca
 9
 GAAUAUGG m6b Disrupted 0.140000 0.032000 0.090000
hsa-miR-5692b tctttctacATATTATTca
 2
 AAUAAUAU m8a (m8a->m7b) 0.486000 0.330000 -0.060000
hsa-miR-5692c tctttctacATATTATTca
 2
 AAUAAUAU m8a (m8a->m7b) 0.486000 0.330000 -0.030000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.94667476A>C COSN9246457 AOCS-145-1-6 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-369-3p gtattagcTATTATaggta
 2
 AAUAAUAC m6b Disrupted 0.230000 0.146000 0.230000
hsa-miR-374a-5p gtattagcTATTATAggta
 2
 UUAUAAUA m7b Disrupted 0.282000 0.189000 0.160000
hsa-miR-374b-5p gtattagcTATTATAggta
 2
 AUAUAAUA m7b Disrupted 0.251000 0.158000 0.030000
hsa-miR-5692b gtattagcTATTATaggta
 2
 AAUAAUAU m6b Disrupted 0.486000 0.398000 0.060000
hsa-miR-5692c gtattagcTATTATaggta
 2
 AAUAAUAU m6b Disrupted 0.486000 0.398000 0.020000
hsa-miR-610 gtaTTAGCTCttataggta
 0 UGAGCUAA m7b (m6b->m7b) no TS -0.203000 -1.130000

Mutation Mutation ID Sample Name Cancer Type
chr4:g.94667848C>G COSN2051794 RK035_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-186-5p taatttcTTCTTTaccccc
 2
 CAAAGAAU m6b Disrupted 0.074000 0.041000 2.100000
hsa-miR-30a-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044000 -0.050000
hsa-miR-30b-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044000 -1.830000
hsa-miR-30c-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044000 -1.160000
hsa-miR-30d-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044000 -0.010000
hsa-miR-30e-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.053000 -0.060000
hsa-miR-186-5p taatttcTTCTTTaccccc
 2
 CAAAGAAU m6b Disrupted 0.074 0.041 2.42
hsa-miR-30a-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044 -0.05
hsa-miR-30b-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044 -1.83
hsa-miR-30c-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044 -1.16
hsa-miR-30d-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.044 -0.01
hsa-miR-30e-5p taatttctTGTTTACcccc
 0 UGUAAACA m7b Created no TS -0.053 -0.06

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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