| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_022894 |
|---|---|
| Gene Symbol: | PAPOLG |
| Description: | Homo sapiens poly(A) polymerase gamma (PAPOLG), mRNA. |
| Gene Location: | chr2(+):60983364-61029221 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60797505C>A | COSN7078982 | 8016470 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3662 |
cctgaacTCATTTTttgtt |
6 |
GAAAAUGA | m7b | Created | 0.512000 | 0.507000 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60798275G>A | COSN7078983 | 8066067 | [pancreas][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4519 |
tttttttaCACTGCTtttt |
0 | CAGCAGUG | m7b | Created | no TS | -0.165000 |
-0.530000 |
|
| hsa-miR-503 |
tttttttaCGCTGCTtttt |
2 |
UAGCAGCG | m7b | Disrupted | -0.244000 | no TS |
0.500000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60798310A>G | COSN6189291 | RK136_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60798538G>A | COSN1849670 | RK056_C01 | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-let-7a-3p |
aatgaaaaTGTATAGatta |
13 |
CUAUACAA | m7a | Disrupted | -0.054000 | -0.054000 | No effect | |
| hsa-let-7b-3p |
aatgaaaaTGTATAGatta |
13 |
CUAUACAA | m7a | Disrupted | -0.054000 | -0.054000 | No effect | |
| hsa-let-7f-1-3p |
aatgaaaaTGTATAGatta |
13 |
CUAUACAA | m7a | Disrupted | -0.074000 | -0.074000 | No effect | |
| hsa-let-7f-2-3p |
aatgaaaaTGTATAGatta |
5 |
CUAUACAG | m7a | Disrupted | 0.077000 | 0.077000 |
0.010000 |
|
| hsa-miR-1284 |
aatgaaaaTGTATAGAtta |
13 |
UCUAUACA | m8a | Disrupted | -0.279000 | -0.250000 | No effect | |
| hsa-let-7a-3p |
aatgaaaaTGTATAGatta |
0 | CUAUACAA | m7a | Disrupted | -0.054 | -0.054 | No effect | |
| hsa-let-7b-3p |
aatgaaaaTGTATAGatta |
0 | CUAUACAA | m7a | Disrupted | -0.054 | -0.054 | No effect | |
| hsa-let-7f-1-3p |
aatgaaaaTGTATAGatta |
0 | CUAUACAA | m7a | Disrupted | -0.074 | -0.074 | No effect | |
| hsa-let-7f-2-3p |
aatgaaaaTGTATAGatta |
0 | CUAUACAG | m7a | Disrupted | 0.077 | 0.077 |
0.01 |
|
| hsa-miR-1284 |
aatgaaaaTGTATAGAtta |
0 | UCUAUACA | m8a | Disrupted | -0.279 | -0.25 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60799424A>C | COSN8560640 | tumor_4163639 | [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][diffuse_large_B_cell_lymphoma] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-567 |
agttgatAACATACTtttg |
8 |
AGUAUGUU | m8a | Created | -0.062000 | -0.044000 |
-0.050000 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60799880G>C | ICGC_6EEEC1A0-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1302 |
tgcctcggcGTCCCAAagt |
0 | UUGGGACA | m7a | (m7a->m6b) | 0.019 | no TS | No effect | |
| hsa-miR-149-3p |
tgcctcggCCTCCCaaagt |
0 | AGGGAGGG | m6b | Created | -0.343 | -0.319 | No effect | |
| hsa-miR-30b-3p |
tgcctcggCCTCCCAaagt |
0 | CUGGGAGG | m7b | Created | -0.605 | -0.531 |
-0.01 |
|
| hsa-miR-30c-1-3p |
tgcctcggcCTCCCAaagt |
0 | CUGGGAGA | m6b | Created | -0.024 | 0.039 | No effect | |
| hsa-miR-30c-2-3p |
tgcctcggcCTCCCAaagt |
0 | CUGGGAGA | m6b | Created | -0.043 | 0.016 | No effect | |
| hsa-miR-3122 |
tgcctcggcGTCCCAAagt |
0 | GUUGGGAC | m7b | (m7b->m6c) | 0 | -0.012 |
0.08 |
|
| hsa-miR-3689a-3p |
tgcctcggCCTCCCAaagt |
0 | CUGGGAGG | m7b | Created | -0.655 | -0.602 | No effect | |
| hsa-miR-3689b-3p |
tgcctcggCCTCCCAaagt |
0 | CUGGGAGG | m7b | Created | -0.664 | -0.611 | No effect | |
| hsa-miR-3689c |
tgcctcggCCTCCCAaagt |
0 | CUGGGAGG | m7b | Created | -0.664 | -0.611 | No effect | |
| hsa-miR-3913-5p |
tgcctcggcGTCCCAAAgt |
0 | UUUGGGAC | m8a | (m8a->m7b) | 0.049 | 0.009 | No effect | |
| hsa-miR-4298 |
tgcctcggcGTCCCAaagt |
0 | CUGGGACA | m6b | Disrupted | 0.002 | no TS | No effect | |
| hsa-miR-4728-5p |
tgcctcggCCTCCCAaagt |
0 | UGGGAGGG | m7a | Created | -0.403 | -0.396 | No effect | |
| hsa-miR-92b-5p |
tgcctcggCGTCCCaaagt |
0 | AGGGACGG | m6b | Disrupted | -0.07 | no TS |
2.21 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60800279G>A | ICGC_96200F4A-2A78-11E2-8335-12FD496BB9B8 | CPCG_0102_Pr_P_P2 | ProstateCancer(OICR,CA) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1247-3p |
ctgccTCCCGGGttcaagt |
2 |
CCCCGGGA | m7b | Disrupted | -0.079 | no TS |
3.63 |
|
| hsa-miR-30b-3p |
ctgCCTCCCAGgttcaagt |
0 | CUGGGAGG | m8a | Created | -0.605 | -0.58 |
-0.14 |
|
| hsa-miR-3192 |
ctgcCTCCCAGgttcaagt |
0 | UCUGGGAG | m7b | Created | -0.07 | -0.047 |
-0.47 |
|
| hsa-miR-3689a-3p |
ctgCCTCCCAGgttcaagt |
0 | CUGGGAGG | m8a | Created | -0.655 | -0.602 |
-0.4 |
|
| hsa-miR-3689b-3p |
ctgCCTCCCAGgttcaagt |
0 | CUGGGAGG | m8a | Created | -0.664 | -0.62 |
-0.22 |
|
| hsa-miR-3689c |
ctgCCTCCCAGgttcaagt |
0 | CUGGGAGG | m8a | Created | -0.664 | -0.62 |
-0.22 |
|
| hsa-miR-490-3p |
ctgcctcCCAGGTTcaagt |
0 | CAACCUGG | m7b | Created | no TS | 0.058 |
-0.46 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60800296T>C | ICGC_96201422-2A78-11E2-8335-12FD496BB9B8 | CPCG_0102_Pr_P_P2 | ProstateCancer(OICR,CA) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-1827 |
gtgattctcCTGCCTCAgc |
0 | UGAGGCAG | m8a | (m7b->m8a) | 0.228 | 0.214 |
-0.13 |
|
| hsa-miR-31-5p |
gtgattcTCTTGCCTcagc |
2 |
AGGCAAGA | m8a | Disrupted | 0.069 | 0.032 | No effect | |
| hsa-miR-3123 |
gtgATTCTCTtgcctcagc |
2 |
CAGAGAAU | m7b | (m7b->m6b) | 0.107 | -0.058 |
0.01 |
|
| hsa-miR-4722-5p |
gtgattCTCCTGCCtcagc |
0 | GGCAGGAG | m8a | Created | no TS | -0.009 |
-0.14 |
|
| hsa-miR-4768-3p |
gtgatTCTCCTGcctcagc |
0 | CCAGGAGA | m7b | Created | -0.063 | -0.006 | No effect | |
| hsa-miR-940 |
gtgattctCCTGCCTcagc |
0 | AAGGCAGG | m7b | Created | -0.187 | -0.17 |
-0.01 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60800395G>C | ICGC_B940A156-2A78-11E2-9C69-1CFD496BB9B8 | CPCG_0103_Pr_P_P3 | ProstateCancer(OICR,CA) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-3620 |
ttggcCAGGGTGgtcttga |
1 |
UCACCCUG | m7b | Disrupted | 0.035 | no TS |
6.06 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60800797A>G | COSN5031027 | HX18T | [liver][NS][carcinoma][NS] | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4764-3p |
atgGGAGTTAgggttagga |
2 |
UUAACUCC | m7b | (m7b->m6b) | 0.029000 | no TS |
-0.570000 |
|
| hsa-miR-652-5p |
atgggagtTAGGGTTagga |
2 |
CAACCCUA | m7b | Disrupted | -0.028000 | no TS | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60801495A>G | ICGC_6EEEC66E-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-20a-3p |
caggctggAATGCAGTggc |
0 | ACUGCAUU | m8a | Disrupted | -0.002 | -0.021 | No effect | |
| hsa-miR-217 |
caggctggaATGCAGTggc |
0 | UACUGCAU | m7b | (m7b->m6c) | 0.027 | 0.059 | No effect | |
| hsa-miR-4793-3p |
caggctggAGTGCAGtggc |
0 | UCUGCACU | m7b | Created | -0.22 | -0.25 | No effect | |
| hsa-miR-508-5p |
caggCTGGAGTgcagtggc |
0 | UACUCCAG | m7b | Created | 0.094 | 0.083 |
-0.01 |
|
| hsa-miR-766-3p |
cagGCTGGAGTgcagtggc |
0 | ACUCCAGC | m8a | Created | 0.064 | 0.011 | No effect | |
| Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
|---|---|---|---|---|---|---|---|---|---|
| chr2:g.60801704T>G | ICGC_6EEECB3C-2A78-11E2-96E7-04FD496BB9B8 | CPCG_0102_Pr_P_P1 | ProstateCancer(OICR,CA) | ||||||
| miRNA Targets Table | |||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
| hsa-miR-4530 |
tcccaaagTGCTGGGatta |
0 | CCCAGCAG | m7a | Created | NA | NA |
-0.01 |
|
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr2:g.60801800G>C | COSN7078984 | 8034061 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-200a-5p |
tgaacaTAAGATGatcatc |
17 |
CAUCUUAC | m7a | Disrupted | 0.006000 | 0.006000 | No effect |
| hsa-miR-200b-5p |
tgaacaTAAGATGatcatc |
17 |
CAUCUUAC | m7a | Disrupted | 0.031000 | 0.031000 |
0.200000 |
| hsa-miR-96-3p |
tgaacataACATGATcatc |
2 |
AAUCAUGU | m7b | Created | 0.002000 | -0.185000 |
-0.010000 |
| Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
|---|---|---|---|---|---|---|---|---|---|
| 60798275 | rs183286075 | G | G |
hsa-miR-503-5p |
2 |
ttttaCGCTGCTt |
Disrupted |
N |
-0.244 |
| A |
hsa-miR-4519 hsa-miR-6499-3p |
2 2 |
ttttaCACTGCTt ttttACACTGCtt |
Created Created |
N N |
-0.165 -0.152 |
|||
| 60799750 | rs13415369 | A | A |
hsa-miR-1273h-5p hsa-miR-149-3p hsa-miR-30b-3p hsa-miR-30c-1-3p hsa-miR-30c-2-3p hsa-miR-3689a-3p hsa-miR-3689b-3p hsa-miR-3689c hsa-miR-4728-5p hsa-miR-6779-5p hsa-miR-6780a-5p hsa-miR-6785-5p hsa-miR-6788-5p hsa-miR-6799-5p hsa-miR-6883-5p hsa-miR-7106-5p hsa-miR-887-5p hsa-miR-890 |
2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 |
CCTCCCAAgtagc CCTCCCAagtagc CCTCCCAAgtagc cCTCCCAAgtagc cCTCCCAAgtagc CCTCCCAAgtagc CCTCCCAAgtagc CCTCCCAAgtagc CCTCCCAagtagc CCTCCCAAgtagc CCTCCCAAgtagc CCTCCCAagtagc cCTCCCAAgtagc CCTCCCAagtagc CCTCCCAagtagc CCTCCCAagtagc cCTCCCAAgtagc cctcCCAAGTAgc |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N N N N N N N N N N |
-0.011 0.001 0.031 0.047 0.041 0.021 0.021 0.021 -0.013 0.021 0.021 0.011 0.044 -0.012 0.011 0.004 0.095 0.073 |
| G |
hsa-miR-6746-5p hsa-miR-6771-5p |
2 2 |
cCTCCCGAgtagc cCTCCCGAgtagc |
Created Created |
N N |
-0.046 -0.029 |
|||
| 60800308 | rs34755107 | - | - |
hsa-miR-1273h-5p hsa-miR-149-3p hsa-miR-30b-3p hsa-miR-30c-1-3p hsa-miR-30c-2-3p hsa-miR-3689a-3p hsa-miR-3689b-3p hsa-miR-3689c hsa-miR-4728-5p hsa-miR-485-5p hsa-miR-6779-5p hsa-miR-6780a-5p hsa-miR-6785-5p hsa-miR-6788-5p hsa-miR-6799-5p hsa-miR-6883-5p hsa-miR-6884-5p hsa-miR-7106-5p hsa-miR-887-5p |
1 2 1 1 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 |
cagCCTCCCAAgt cagCCTCCCAagt cagCCTCCCAAgt cagcCTCCCAAgt cagcCTCCCAAgt cagCCTCCCAAgt cagCCTCCCAAgt cagCCTCCCAAgt cagCCTCCCAagt CAGCCTCccaagt cagCCTCCCAAgt cagCCTCCCAAgt cagCCTCCCAagt cagcCTCCCAAgt cagCCTCCCAagt cagCCTCCCAagt CAGCCTCccaagt cagCCTCCCAagt cagcCTCCCAAgt |
Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown |
N N N N N N N N N N N N N N N N N N N |
-0.014 No Change 0.028 0.044 0.038 0.018 0.018 0.018 -0.014 -0.014 0.018 0.018 0.01 0.041 -0.013 0.01 -0.014 0.003 0.092 |
| C |
hsa-miR-1343-5p hsa-miR-2110 hsa-miR-3150a-3p hsa-miR-3175 hsa-miR-450a-2-3p hsa-miR-6763-5p hsa-miR-6810-5p hsa-miR-6825-5p hsa-miR-6857-5p hsa-miR-939-5p |
1 1 1 1 1 1 1 1 1 1 |
cagcCTCCCCAagt cagccTCCCCAAgt cagcCTCCCCAAgt cagcCTCCCCAagt cagccTCCCCAAgt cagcCTCCCCAAgt cagccTCCCCAAgt cagCCTCCCCAagt cagccTCCCCAAgt cagcCTCCCCAagt |
Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown Unknown |
N N N N N N N N N N |
-0.004 0.024 0.007 -0.013 0.064 -0.003 0.015 -0.078 0.003 -0.028 |
|||
| 60800709 | rs147782727 | G | G |
hsa-let-7a-3p hsa-let-7b-3p hsa-let-7f-1-3p hsa-let-7f-2-3p hsa-miR-1185-1-3p hsa-miR-1185-2-3p hsa-miR-4731-3p hsa-miR-4789-5p hsa-miR-4801 hsa-miR-98-3p |
5 5 5 5 5 5 5 5 5 5 |
aattgTGTATAAg aattgTGTATAAg aattgTGTATAAg aattgTGTATAAg aattgTGTATAAg aattgTGTATAAg aaTTGTGTAtaag aattGTGTATAAg aaTTGTGTAtaag aattgTGTATAAg |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N N |
0.093 0.093 0.083 0.085 0.085 0.085 0.04 0.009 0.026 0.086 |
| T |
hsa-miR-340-5p |
5 |
aattgTTTATAAg |
Created |
N |
0.15 |
|||
| 60800774 | rs181834350 | G | |||||||
| T |
hsa-miR-1303 hsa-miR-3123 hsa-miR-3925-5p |
2 2 2 |
ctTCTCTAAgtgg cTTCTCTAagtgg cTTCTCTAagtgg |
Created Created Created |
N N N |
0.035 0.063 0.066 |
|||
| 60801796 | rs181789516 | A | |||||||
| G |
hsa-miR-200a-5p hsa-miR-200b-5p |
8 8 |
ttgaacGTAAGAT ttgaacGTAAGAT |
Created Created |
N N |
-0.12 -0.12 |