SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_198074 |
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Gene Symbol: | OR2C3 |
Description: | Homo sapiens olfactory receptor, family 2, subfamily C, member 3 (OR2C3), mRNA. |
Gene Location: | chr1(-):247693433-247697141 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr1:g.247530391A>G | COSN7214612 | 8036161 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-548p |
ttttgTTTTGCTtatctat |
0 | UAGCAAAA | m7b | Created | -0.307000 | -0.425000 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr1:g.247530527T>G | COSN1101659 | HCC122T | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr1:g.247530602G>A | COSN7470017 | tumor_4135099 | [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-302c-5p |
ctgatacATGTTAAAatta |
2 |
UUUAACAU | m8a | Disrupted | -0.203000 | -0.102000 |
0.510000 |
|
hsa-miR-3143 |
ctgatacATGTTAaaatta |
2 |
AUAACAUU | m6b | Disrupted | -0.086000 | -0.071000 |
2.920000 |
|
hsa-miR-3924 |
ctgATACATATtaaaatta |
0 | AUAUGUAU | m8a | Created | no TS | -0.076000 | No effect | |
hsa-miR-4517 |
ctgataCATATTaaaatta |
2 |
AAAUAUGA | m6b | Created | -0.060000 | -0.071000 | No effect | |
hsa-miR-5583-3p |
ctgataCATATTaaaatta |
0 | GAAUAUGG | m6b | Created | no TS | -0.017000 |
-0.610000 |
|
hsa-miR-889 |
ctgatacATATTAAaatta |
0 | UUAAUAUC | m7a | Created | no TS | 0.026000 |
-0.010000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr1:g.247530935C>A | COSN5370101 | RK169_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-1231 |
gacCCAGACAaagaccgcg |
0 | GUGUCUGG | m7b | (m6c->m7b) | no TS | -0.123000 |
-2.270000 |
|
hsa-miR-4288 |
gaccCAGACAAagaccgcg |
0 | UUGUCUGC | m7a | Created | no TS | 0.001000 |
-2.170000 |
|
hsa-miR-4527 |
gaccCAGACCAagaccgcg |
2 |
UGGUCUGC | m7a | Disrupted | -0.253000 | -0.208000 |
3.130000 |
|
hsa-miR-632 |
gaccCAGACAaagaccgcg |
0 | GUGUCUGC | m6b | Created | no TS | -0.016000 |
-10.860000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr1:g.247531196G>A | COSN7214613 | 8031146 | [pancreas][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr1:g.247531424G>A | COSN7470018 | tumor_4120193 | [haematopoietic_and_lymphoid_tissue][NS][lymphoid_neoplasm][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-10b-3p |
tggaAATCTGaaaggagtg |
5 |
ACAGAUUC | m6b | Disrupted | -0.062000 | no TS |
2.450000 |
|
hsa-miR-376a-5p |
tggaAATCTAaaaggagtg |
0 | GUAGAUUC | m6b | Created | no TS | -0.051000 |
-7.100000 |
|
hsa-miR-3942-3p |
tggaaATCTGAAAggagtg |
3 |
UUUCAGAU | m8a | Disrupted | -0.201000 | no TS |
0.850000 |
|
hsa-miR-4760-5p |
tggaAATCTAAAaggagtg |
2 |
UUUAGAUU | m8a | Created | -0.019000 | -0.193000 |
-0.112000 |
|
hsa-miR-5100 |
tggaaATCTGAAaggagtg |
3 |
UUCAGAUC | m7a | Disrupted | -0.077000 | no TS |
0.050000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr1:g.247531437T>A | COSN8637975 | J36_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-141-5p |
agctcaaGGAAGATGgaaa |
2 |
CAUCUUCC | m8a | Created | -0.216000 | -0.395000 |
-6.100000 |
|
hsa-miR-3200-3p |
agctCAAGGTagatggaaa |
5 |
CACCUUGC | m6b | Disrupted | -0.145000 | no TS |
9.180000 |
|
hsa-miR-502-5p |
agctCAAGGAagatggaaa |
0 | AUCCUUGC | m6b | Created | no TS | -0.102000 |
-0.680000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr1:g.247531447G>A | COSN8637976 | 360_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-27b-5p |
atattgttTAAGCTCaagg |
0 | AGAGCUUA | m7b | Created | no TS | -0.422000 |
-0.210000 |
|
hsa-miR-302a-5p |
atattGTTTAAGctcaagg |
0 | ACUUAAAC | m7b | Created | no TS | -0.123000 |
-0.720000 |
|
hsa-miR-3670 |
atattgttTGAGCTCaagg |
3 |
AGAGCUCA | m7b | Disrupted | -0.436000 | no TS | No effect | |
hsa-miR-371a-5p |
atattGTTTGAGctcaagg |
4 |
ACUCAAAC | m7b | Disrupted | -0.130000 | -0.002000 |
1.760000 |
|
hsa-miR-590-5p |
atattgttTAAGCTCaagg |
0 | GAGCUUAU | m7a | Created | NA | NA |
-2.980000 |
Mutation | Mutation ID | Sample Name | Cancer Type | ||||||
---|---|---|---|---|---|---|---|---|---|
chr1:g.247531459C>G | COSN1441361 | RK027_C01 | [liver][NS][carcinoma][NS] | ||||||
miRNA Targets Table | |||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change | |
hsa-miR-3185 |
gtttTTCTTCTaatattgt |
0 | AGAAGAAG | m7a | Disrupted | NA | NA |
0.010000 |
|
hsa-miR-5197-3p |
gttttTCTTCTaatattgt |
0 | AAGAAGAG | m6b | Disrupted | -0.126000 | -0.031000 | No effect | |
hsa-miR-3185 |
gtttTTCTTCTaatattgt |
0 | AGAAGAAG | m7a | Disrupted | NA | NA |
0.01 |
|
hsa-miR-5197-3p |
gttttTCTTCTaatattgt |
0 | AAGAAGAG | m6b | Disrupted | -0.126 | -0.031 | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr1:g.247531482G>T | COSN8637977 | J36_T | [lung][NS][carcinoma][squamous_cell_carcinoma] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-146b-3p |
gaagACAGGGCActtggga |
1 |
UGCCCUGU | m8a | Disrupted | -0.428000 | no TS |
4.640000 |
hsa-miR-339-5p |
gaaGACAGGGcacttggga |
1 |
UCCCUGUC | m7b | (m7b->m6c) | -0.275000 | no TS |
13.090000 |
hsa-miR-371b-3p |
gaagacaGGGCACTTggga |
1 |
AAGUGCCC | m8a | Disrupted | -0.288000 | no TS |
4.850000 |
hsa-miR-4421 |
gaAGACAGGTcacttggga |
1 |
ACCUGUCU | m8a | (m7b->m8a) | -0.210000 | -0.238000 |
1.340000 |
hsa-miR-631 |
gaagaCAGGTCacttggga |
0 | AGACCUGG | m6b | Created | no TS | -0.154000 |
-0.040000 |
hsa-miR-874 |
gaagaCAGGGCActtggga |
1 |
CUGCCCUG | m7b | Disrupted | -0.279000 | no TS |
2.300000 |
Location | SNP ID | Ancestral Allele |
Allele | miR ID | Conservation | miRSite | FuncClass | Validation | context+ score change |
---|---|---|---|---|---|---|---|---|---|
247530602 | rs73146580 | G | G |
hsa-miR-302c-5p hsa-miR-3143 hsa-miR-552-5p |
2 2 2 |
atacATGTTAAAa atacATGTTAAaa atacatGTTAAAA |
Disrupted Disrupted Disrupted |
N N N |
-0.101 -0.015 0.013 |
A |
hsa-miR-3924 hsa-miR-4517 hsa-miR-5583-3p hsa-miR-889-3p |
1 1 1 2 |
ATACATAttaaaa ataCATATTAaaa ataCATATTAaaa atacATATTAAaa |
Created Created Created Created |
N N N N |
-0.076 -0.011 -0.017 0.026 |
|||
247531457 | rs73148444 | A | A |
hsa-miR-16-2-3p hsa-miR-195-3p hsa-miR-5197-3p |
3 3 1 |
tcttctAATATTG tcttctAATATTG TCTTCTAatattg |
Disrupted Disrupted Disrupted |
N N N |
-0.056 -0.056 -0.095 |
G |
hsa-miR-2115-3p hsa-miR-3074-3p hsa-miR-361-5p |
1 2 1 |
tcTTCTGATAttg tcttCTGATATtg tctTCTGATAttg |
Created Created Created |
N N N |
-0.244 -0.157 -0.158 |
|||
247531483 | rs141481931 | G | G |
hsa-miR-146b-3p hsa-miR-3173-5p hsa-miR-339-5p hsa-miR-371b-3p hsa-miR-4421 hsa-miR-5699-3p hsa-miR-6799-3p hsa-miR-7976 hsa-miR-874-3p |
1 1 1 1 1 1 1 1 1 |
agACAGGGCActt agaCAGGGCActt aGACAGGGcactt agacaGGGCACTt AGACAGGgcactt AGACAGGgcactt agaCAGGGCActt agaCAGGGCActt agaCAGGGCActt |
Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted Disrupted |
N N N N N N N N N |
-0.428 -0.182 -0.275 -0.288 -0.21 -0.182 -0.185 -0.187 -0.279 |
A |
hsa-miR-302a-3p hsa-miR-302b-3p hsa-miR-302c-3p hsa-miR-302d-3p hsa-miR-302e hsa-miR-3120-5p hsa-miR-3194-3p hsa-miR-372-3p hsa-miR-373-3p hsa-miR-520a-3p hsa-miR-520b hsa-miR-520c-3p hsa-miR-520d-3p hsa-miR-520e hsa-miR-5691 hsa-miR-6805-3p hsa-miR-6888-3p |
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 |
agacagAGCACTT agacagAGCACTT agacagAGCACTT agacagAGCACTT agacagAGCACTT AGACAGAgcactt agaCAGAGCActt agacagAGCACTT agacagAGCACTT agacagAGCACTT agacagAGCACTT agacagAGCACTT agacagAGCACTT agacagAGCACTT agaCAGAGCActt agaCAGAGCActt AGACAGAgcactt |
Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created Created |
N N N N N N N N N N N N N N N N N |
-0.113 -0.113 -0.113 -0.113 -0.113 -0.08 -0.136 -0.103 -0.103 -0.113 -0.103 -0.103 -0.122 -0.103 -0.215 -0.205 -0.144 |