SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database

Prediction criteria: TargetScan sites only     All 6mer or longer seed matches

RefSeq ID: NM_006185
Gene Symbol: NUMA1
Description: Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), mRNA.
Gene Location: chr11(-):71713910-71791573
Browse Associations

Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr11:g.72002948G>T COSN5918001 RK135_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1283 tgggaTTTGTAGtgatggg
0 UCUACAAA m7b Created no TS -0.038000 -1.250000
hsa-miR-3145-5p tgggatTTGGAGTgatggg
8
AACUCCAA m7b Disrupted -0.156000 no TS 3.880000
hsa-miR-34c-3p tgggatttgTAGTGATggg
0 AAUCACUA m7b (m6b->m7b) no TS -0.090000 -1.420000
hsa-miR-4762-5p tggGATTTGGagtgatggg
5
CCAAAUCU m7a (m7a->m6b) -0.074000 -0.074000 -1.360000

Mutation Mutation ID Sample Name Cancer Type
chr11:g.72003188C>G COSN1542208 RK166_C01 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3975 tctTAGCCTCtggatctag
2
UGAGGCUA m7b (m7b->m6c) -0.161000 no TS 2.520000
hsa-miR-4257 tcttagCCTCTGGatctag
0 CCAGAGGU m7a Disrupted NA NA 0.020000
hsa-miR-4438 tcttAGCCTGTGgatctag
0 CACAGGCU m8a Created no TS -0.186000 -2.490000
hsa-miR-520a-5p tcttagcCTCTGGAtctag
0 CUCCAGAG m7b Disrupted -0.107000 no TS 3.630000
hsa-miR-525-5p tcttagcCTCTGGAtctag
0 CUCCAGAG m7b Disrupted -0.089000 no TS 3.630000
hsa-miR-3975 tctTAGCCTCtggatctag
2
UGAGGCUA m7b (m7b->m6c) -0.161000 no TS 2.520000
hsa-miR-4257 tcttagCCTCTGGatctag
0 CCAGAGGU m7a Disrupted NA NA 0.020000
hsa-miR-4438 tcttAGCCTGTGgatctag
0 CACAGGCU m8a Created no TS -0.186000 -2.490000
hsa-miR-520a-5p tcttagcCTCTGGAtctag
0 CUCCAGAG m7b Disrupted -0.107000 no TS 3.630000
hsa-miR-525-5p tcttagcCTCTGGAtctag
0 CUCCAGAG m7b Disrupted -0.089000 no TS 3.630000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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