SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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RefSeq ID: | NM_001010848 |
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Gene Symbol: | NRG3 |
Description: | Homo sapiens neuregulin 3 (NRG3), transcript variant 1, mRNA. |
Gene Location: | chr10(+):83635069-84746935 |
Browse Associations | |
Browse Pathways |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr10:g.82985839T>A | COSN1503513 | RK025_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr10:g.82985850C>A | NRG3_E9_UTR_3 | SJHYPO021_D | Hypodiploid_ALL | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1269a |
gtttAGTCCAaacactgtc |
0 | CUGGACUG | m6b | Created | no TS | -0.148 |
-2.84 |
hsa-miR-1269b |
gtttAGTCCAaacactgtc |
0 | CUGGACUG | m6b | Created | no TS | -0.151 |
-2.94 |
hsa-miR-3122 |
gtttaGTCCCAACactgtc |
9 |
GUUGGGAC | m8a | Disrupted | -0.301 | -0.095 |
2.9 |
hsa-miR-3147 |
gtttagtCCCAACactgtc |
8 |
GGUUGGGC | m6b | Disrupted | -0.146 | no TS |
0.29 |
hsa-miR-3199 |
gtttAGTCCCaacactgtc |
10 |
AGGGACUG | m6b | Disrupted | -0.467 | -0.299 |
2.21 |
hsa-miR-365a-5p |
gtttAGTCCCaacactgtc |
10 |
AGGGACUU | m6b | Disrupted | -0.291 | -0.12 |
3.44 |
hsa-miR-365b-5p |
gtttAGTCCCaacactgtc |
10 |
AGGGACUU | m6b | Disrupted | -0.287 | -0.12 |
0.13 |
hsa-miR-3913-5p |
gtttaGTCCCAAcactgtc |
9 |
UUUGGGAC | m7b | Disrupted | -0.292 | -0.086 |
2.8 |
hsa-miR-4298 |
gtttaGTCCCAacactgtc |
9 |
CUGGGACA | m6b | Disrupted | -0.275 | -0.104 |
0.66 |
hsa-miR-4425 |
gtttagTCCCAACActgtc |
7 |
UGUUGGGA | m8a | Disrupted | -0.321 | no TS |
9.92 |
hsa-miR-4529-3p |
gtttAGTCCAAacactgtc |
0 | AUUGGACU | m7b | Created | no TS | -0.354 |
-4.84 |
hsa-miR-5009-5p |
gtttAGTCCAAacactgtc |
0 | UUGGACUU | m7a | Created | no TS | -0.155 |
-0.14 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr10:g.82985973G>A | 0_346 | Small cell lung cancer | ||||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-4648 |
ctgcaTCCCACAggtggat |
3 |
UGUGGGAC | m7a | Created | no TS | -0.104 |
-0.15 |
hsa-miR-4654 |
ctgcATCCCACAggtggat |
3 |
UGUGGGAU | m8a | Created | no TS | -0.232 |
-0.09 |
hsa-miR-4734 |
ctgcatCCCGCAGgtggat |
3 |
GCUGCGGG | m7b | Disrupted | -0.264 | no TS |
15.6 |
hsa-miR-4769-5p |
ctgcATCCCACaggtggat |
3 |
GGUGGGAU | m7b | Created | no TS | -0.232 |
-0.38 |
hsa-miR-5187-5p |
ctgCATCCCAcaggtggat |
3 |
UGGGAUGA | m7a | (m6a->m7a) | no TS | -0.096 |
-0.02 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr10:g.82986203C>T | COSN6405705 | HX36T | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3125 |
gccaccTTCCTCTgagatt |
7 |
UAGAGGAA | m7b | Disrupted | -0.053000 | no TS | No effect |
hsa-miR-3185 |
gccacCTTCTTCTgagatt |
0 | AGAAGAAG | m8a | Created | no TS | 0.005000 |
-1.290000 |
hsa-miR-3916 |
gccaccTTCCTCTgagatt |
7 |
AAGAGGAA | m7b | Disrupted | -0.063000 | no TS | No effect |
hsa-miR-4257 |
gccaccttCCTCTGagatt |
10 |
CCAGAGGU | m6b | Disrupted | -0.071000 | no TS |
-6.540000 |
hsa-miR-4476 |
gccaCCTTCCTctgagatt |
2 |
CAGGAAGG | m7b | Disrupted | -0.080000 | no TS | No effect |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr10:g.82986315C>T | COSN5291968 | RK156_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3148 |
aatgTTTTTCCttgagatt |
3 |
UGGAAAAA | m7b | Disrupted | -0.282000 | -0.311000 | No effect |
hsa-miR-561-5p |
aatgttttTCCTTGAgatt |
3 |
AUCAAGGA | m7b | Disrupted | -0.177000 | no TS |
0.180000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr10:g.82986526A>G | COSN1503514 | RK046_C02 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-1200 |
actatTCAGGAaaattatt |
0 | CUCCUGAG | m6b | Created | no TS | -0.100000 | No effect |
hsa-miR-3074-5p |
actattCAGGAAaattatt |
12 |
GUUCCUGC | m6b | Created | -0.111000 | -0.190000 |
-0.040000 |
hsa-miR-3140-5p |
actATTCAGGaaaattatt |
15 |
ACCUGAAU | m7b | (m6b->m7b) | -0.102000 | -0.303000 |
-0.010000 |
hsa-miR-378a-5p |
actatTCAGGAaaattatt |
0 | CUCCUGAC | m6b | Created | no TS | -0.106000 |
-7.110000 |
hsa-miR-4427 |
acTATTCAGAaaaattatt |
6 |
UCUGAAUA | m8a | (m8a->m7a) | -0.216000 | -0.149000 |
0.050000 |
hsa-miR-4680-3p |
actATTCAGAaaaattatt |
6 |
UCUGAAUU | m7a | (m7a->m6a) | -0.043000 | -0.017000 | No effect |
hsa-miR-4762-3p |
actatTCAGAAaaattatt |
0 | CUUCUGAU | m6b | Disrupted | -0.057000 | no TS |
12.670000 |
hsa-miR-1200 |
actatTCAGGAaaattatt |
0 | CUCCUGAG | m6b | Created | no TS | -0.1 | No effect |
hsa-miR-3074-5p |
actattCAGGAAaattatt |
0 | GUUCCUGC | m6b | Created | -0.111 | -0.19 |
-0.04 |
hsa-miR-3140-5p |
actATTCAGGaaaattatt |
0 | ACCUGAAU | m7b | (m6b->m7b) | -0.102 | -0.303 |
-0.01 |
hsa-miR-378a-5p |
actatTCAGGAaaattatt |
0 | CUCCUGAC | m6b | Created | no TS | -0.106 |
-7.11 |
hsa-miR-4427 |
acTATTCAGAaaaattatt |
0 | UCUGAAUA | m8a | (m8a->m7a) | -0.216 | -0.149 |
0.05 |
hsa-miR-4680-3p |
actATTCAGAaaaattatt |
0 | UCUGAAUU | m7a | (m7a->m6a) | -0.043 | -0.017 | No effect |
hsa-miR-4762-3p |
actatTCAGAAaaattatt |
0 | CUUCUGAU | m6b | Disrupted | -0.057 | no TS |
12.67 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr10:g.82986544A>G | COSN5886306 | RK308_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-3156-5p |
ttccctcttAGATCTTTtc |
0 | AAAGAUCU | m8a | (m8a->m7b) | -0.167000 | no TS |
1.680000 |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr10:g.82986692C>T | COSN5886307 | RK150_C01 | [liver][NS][carcinoma][NS] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
Mutation | Mutation ID | Sample Name | Cancer Type | |||||
---|---|---|---|---|---|---|---|---|
chr10:g.82986849T>G | COSN8723193 | AOCS-134-3-9 | [ovary][NS][other][neoplasm] | |||||
miRNA Targets Table | ||||||||
miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
hsa-miR-103b |
tagcaagtcGGCTATGtgt |
0 | UCAUAGCC | m7b | (m6c->m7b) | no TS | -0.163000 |
-2.570000 |
hsa-miR-4771 |
tagcaAGTCTGCTatgtgt |
4 |
AGCAGACU | m8a | Disrupted | -0.251000 | no TS |
3.410000 |
hsa-miR-499b-5p |
tagcAAGTCTGctatgtgt |
4 |
ACAGACUU | m7b | Disrupted | -0.111000 | no TS |
2.020000 |