| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_013957 |
|---|---|
| Gene Symbol: | NRG1 |
| Description: | Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1c, mRNA. |
| Gene Location: | chr8(+):32405727-32622558 |
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| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr8:g.32764430G>A | COSN2272614 | RK027_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-125a-3p |
gatTCACCTGTaaaacttt |
17 |
ACAGGUGA | m8a | Disrupted | -0.338000 | no TS |
1.240000 |
| hsa-miR-5095 |
gattcaCCTGTAAaacttt |
18 |
UUACAGGC | m7a | Disrupted | -0.165000 | no TS |
6.050000 |
| hsa-miR-552 |
gattCACCTGTaaaacttt |
17 |
AACAGGUG | m7b | Disrupted | -0.507000 | no TS |
4.120000 |
| hsa-miR-125a-3p |
gatTCACCTGTaaaacttt |
17 |
ACAGGUGA | m8a | Disrupted | -0.338 | no TS |
1.24 |
| hsa-miR-5095 |
gattcaCCTGTAAaacttt |
18 |
UUACAGGC | m7a | Disrupted | -0.165 | no TS |
6.05 |
| hsa-miR-552 |
gattCACCTGTaaaacttt |
17 |
AACAGGUG | m7b | Disrupted | -0.507 | no TS |
4.12 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr8:g.32764962A>G | COSN2272615 | RK082_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-103a-3p |
cagcATGCTGCTattaaat |
0 | AGCAGCAU | m8a | Created | no TS | -0.217000 |
-3.140000 |
| hsa-miR-107 |
cagcATGCTGCTattaaat |
0 | AGCAGCAU | m8a | Created | no TS | -0.217000 |
-1.740000 |
| hsa-miR-15a-5p |
cagcaTGCTGCTAttaaat |
0 | UAGCAGCA | m8a | Created | no TS | -0.452000 |
-3.850000 |
| hsa-miR-15b-5p |
cagcaTGCTGCTAttaaat |
0 | UAGCAGCA | m8a | Created | no TS | -0.452000 |
-7.950000 |
| hsa-miR-16-5p |
cagcaTGCTGCTAttaaat |
0 | UAGCAGCA | m8a | Created | no TS | -0.421000 |
-4.450000 |
| hsa-miR-195-5p |
cagcaTGCTGCTAttaaat |
0 | UAGCAGCA | m8a | Created | no TS | -0.421000 |
-4.450000 |
| hsa-miR-424-5p |
cagcaTGCTGCTattaaat |
0 | CAGCAGCA | m7b | Created | no TS | -0.463000 |
-4.270000 |
| hsa-miR-4524a-5p |
cagcatGCTGCTATtaaat |
0 | AUAGCAGC | m8a | Created | no TS | -0.311000 |
-5.200000 |
| hsa-miR-4524b-5p |
cagcatGCTGCTATtaaat |
0 | AUAGCAGC | m8a | Created | no TS | -0.311000 |
-5.200000 |
| hsa-miR-497-5p |
cagcaTGCTGCTattaaat |
0 | CAGCAGCA | m7b | Created | no TS | -0.452000 |
-9.450000 |
| hsa-miR-633 |
cagcatgctACTATTAaat |
13 |
CUAAUAGU | m7b | (m7b->m6c) | -0.209000 | -0.045000 |
0.690000 |
| hsa-miR-646 |
cagcatGCTGCTattaaat |
0 | AAGCAGCU | m6b | Created | no TS | -0.196000 |
-12.500000 |