| SomamiR DB 2.0 Somatic mutations altering microRNA-ceRNA interactions |
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| RefSeq ID: | NM_001160008 |
|---|---|
| Gene Symbol: | NRG1 |
| Description: | Homo sapiens neuregulin 1 (NRG1), transcript variant HRG-beta1c, mRNA. |
| Gene Location: | chr8(+):32405727-32618507 |
| Browse Associations | |
| Browse Pathways | |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr8:g.32760486G>A | COSN8855396 | SS6003109 | [oesophagus][NS][carcinoma][adenocarcinoma] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1200 |
tcacCTCAGGAaatctact |
3 |
CUCCUGAG | m7b | Disrupted | -0.314000 | no TS |
3.510000 |
| hsa-miR-3074-5p |
tcacctCAGGAAatctact |
2 |
GUUCCUGC | m6b | Disrupted | -0.083000 | no TS |
2.370000 |
| hsa-miR-378a-5p |
tcaccTCAGGAaatctact |
3 |
CUCCUGAC | m6b | Disrupted | -0.110000 | no TS |
1.160000 |
| hsa-miR-4303 |
tcacCTCAGAAaatctact |
0 | UUCUGAGC | m7a | Created | -0.068000 | -0.191000 |
-1.140000 |
| hsa-miR-4324 |
tcacCTCAGGaaatctact |
4 |
CCCUGAGA | m6b | Disrupted | -0.149000 | no TS | No effect |
| hsa-miR-4649-3p |
tcaCCTCAGAaaatctact |
7 |
UCUGAGGC | m7a | (m6a->m7a) | -0.229000 | -0.347000 |
-0.010000 |
| hsa-miR-4762-3p |
tcaccTCAGAAaatctact |
5 |
CUUCUGAU | m6b | Created | -0.161000 | -0.218000 |
-1.890000 |
| hsa-miR-544b |
tcaCCTCAGGaaatctact |
4 |
ACCUGAGG | m7b | (m7b->m6b) | -0.428000 | no TS |
2.110000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr8:g.32760653G>A | COSN8080535 | 8058344 | [pancreas][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |
| hsa-miR-1237 |
ctttgatgCAGAAGGtgca |
0 | UCCUUCUG | m7b | Created | no TS | -0.108000 |
-0.700000 |
| hsa-miR-20a-3p |
ctttgATGCAGaaggtgca |
0 | ACUGCAUU | m6b | Created | no TS | -0.101000 |
-1.510000 |
| hsa-miR-544a |
ctttgaTGCAGAAggtgca |
0 | AUUCUGCA | m7b | Created | no TS | -0.131000 |
-0.640000 |
| Mutation | Mutation ID | Sample Name | Cancer Type | |||||
|---|---|---|---|---|---|---|---|---|
| chr8:g.32760871C>A | COSN2272613 | RK037_C01 | [liver][NS][carcinoma][NS] | |||||
| miRNA Targets Table | ||||||||
| miR ID | miRSite | Conservation | miRSeed | SeedClass | FuncClass | Wildtype CS+ | Mutant CS+ | PITA score change |