SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_005921
Gene Symbol: MAP3K1
Description: Homo sapiens mitogen-activated protein kinase kinase kinase 1 (MAP3K1), mRNA.
Gene Location: chr5(+):56110899-56191978
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Somatic mutations that impact miRNA target sites



Mutation Mutation ID Sample Name Cancer Type
chr5:g.56893755A>G COSN1317328 HCC66T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
No TargetScan sites are altered. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.


Mutation Mutation ID Sample Name Cancer Type
chr5:g.56894505C>A COSN9953947 C0034T [kidney][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-134 agtCAGTCACcactcttat
 0 UGUGACUG m7b (m7b->m6b) -0.115000 no TS 0.530000
hsa-miR-3118 agtCAGTCACcactcttat
 0 UGUGACUG m7b (m7b->m6b) -0.143000 no TS 0.520000
hsa-miR-3659 agtcagtcAACACTCttat
 0 UGAGUGUU m7b Created no TS -0.095000 -3.580000
hsa-miR-4439 agTCAGTCACcactcttat
 0 GUGACUGA m8a (m8a->m7a) -0.058000 -0.157000 -0.220000

Mutation Mutation ID Sample Name Cancer Type
chr5:g.56894532A>G COSN9452353 AOCS-159-1-9 [ovary][NS][other][neoplasm]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-486-5p ttaaGTACAGGttaactaa
 0 UCCUGUAC m7b Created no TS -0.235000 -2.870000
hsa-miR-490-3p ttaagtaCAGGTTaactaa
 11
 CAACCUGG m6b Created -0.059000 -0.116000 -0.620000
hsa-miR-649 ttaagtACAGGTTaactaa
 11
 AAACCUGU m7b Created -0.086000 -0.289000 -1.460000

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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