SomamiR DB 2.0
Somatic mutations altering microRNA-ceRNA interactions
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PolymiRTS Database
Prediction criteria: TargetScan sites only     All 6mer or longer seed matches
RefSeq ID: NM_003994
Gene Symbol: KITLG
Description: Homo sapiens KIT ligand (KITLG), transcript variant b, mRNA.
Gene Location: chr12(-):88886569-88974250
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Browse Pathways

Somatic mutations that impact miRNA target sites


Mutation Mutation ID Sample Name Cancer Type
chr12:g.88493359C>T 0_18 Melanoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-1246 agaaatAATCCATgctaaa
 15
 AAUGGAUU m7b Disrupted -0.128 no TS No effect
hsa-miR-183-3p agaaaTAATTCAtgctaaa
 15
 GUGAAUUA m7b Created 0.204 0.149 No effect
hsa-miR-490-5p agaaataATCCATGctaaa
 16
 CCAUGGAU m7b Disrupted -0.188 no TS No effect
hsa-miR-944 agaAATAATTcatgctaaa
 15
 AAAUUAUU m7b (m6c->m7b) no TS 0.051 No effect

Mutation Mutation ID Sample Name Cancer Type
chr12:g.88495229A>T ICGC_sm74439 RK006_C02 [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-5007-3p tgcttgagCATATGAaaat
 0 AUCAUAUG m7b Disrupted 0.064 no TS 0.47
hsa-miR-99a-3p tgcttGAGCTTatgaaaat
 0 CAAGCUCG m6b Created no TS -0.036 -0.12
hsa-miR-99b-3p tgcttGAGCTTatgaaaat
 0 CAAGCUCG m6b Created no TS -0.036 -0.83

Mutation Mutation ID Sample Name Cancer Type
chr12:g.88495672C>T 0_19 Melanoma
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-3646 ctttcctTTCATTTcaaaa
 8
 AAAAUGAA m7b Disrupted 0.241 0.101 2.35
hsa-miR-488-3p ctttCCTTTCAtttcaaaa
 8
 UUGAAAGG m7b Disrupted -0.02 no TS No effect
hsa-miR-5681a ctttCCTTTCatttcaaaa
 20
 AGAAAGGG m6b Disrupted 0.034 -0.003 0.06

Mutation Mutation ID Sample Name Cancer Type
chr12:g.88497127A>G ICGC_ssm_v3_46644 HCC116T [liver][NS][carcinoma][NS]
miRNA Targets Table
miR ID miRSite Conservation miRSeed SeedClass FuncClass Wildtype CS+ Mutant CS+ PITA score change
hsa-miR-4517 caaatTCATATTctgtctg
 0 AAAUAUGA m7b Disrupted 0.018 0.142 No effect
hsa-miR-589-3p caaattcaTGTTCTGtctg
 0 UCAGAACA m7b Created 0.052 -0.122 -0.25

*By default, only target sites identified by TargetScan are displayed. To display all potentially impacted target sites, select "All 6mer or longer seed matches" above.



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